Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations [0]
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- Product number
- 20139-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MCT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MCT1 antibody (Cat. #20139-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Combination of Exercise and Intake of Amino Acid Mixture Synergistically Induces Beige Adipocyte Formation in Mice.
MCT2 overexpression promotes recovery of cognitive function by increasing mitochondrial biogenesis in a rat model of stroke.
Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice.
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis.
Immunoreactivity and a new staining method of monocarboxylate transporter 1 located in endothelial cells of cerebral vessels of human brain in distinguishing cerebral venules from arterioles.
Monocarboxylate transporter 1 promotes proliferation and invasion of renal cancer cells by mediating acetate transport.
hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling.
In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment.
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Pinocembrin attenuates hemorrhagic transformation after delayed t-PA treatment in thromboembolic stroke rats by regulating endogenous metabolites.
ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system.
Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies.
Low levels of AMPK promote epithelial-mesenchymal transition in lung cancer primarily through HDAC4- and HDAC5-mediated metabolic reprogramming.
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications.
Acidic Stress Triggers Sodium-Coupled Bicarbonate Transport and Promotes Survival in A375 Human Melanoma Cells.
Subacute ruminal acidosis suppressed the expression of MCT1 in rumen of cows.
Rno-miR-425-5p targets the DLST and SLC16A1 genes to reduce liver damage caused by excessive energy mobilization under cold stress.
Monocarboxylate transporter 1 is an independent prognostic factor in esophageal squamous cell carcinoma.
Tumoral microvesicle-activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma.
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.
Lanthanum damages learning and memory and suppresses astrocyte-neuron lactate shuttle in rat hippocampus.
Kojima T, Esaki N, Tsuda T
Journal of nutritional science and vitaminology 2021;67(4):225-233
Journal of nutritional science and vitaminology 2021;67(4):225-233
MCT2 overexpression promotes recovery of cognitive function by increasing mitochondrial biogenesis in a rat model of stroke.
Yu X, Zhang R, Wei C, Gao Y, Yu Y, Wang L, Jiang J, Zhang X, Li J, Chen X
Animal cells and systems 2021;25(2):93-101
Animal cells and systems 2021;25(2):93-101
Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice.
Liu Q, Liu S, Cao H, Ji W, Li C, Huan Y, Lei L, Fu Y, Gao X, Liu Y, Shen Z
Frontiers in pharmacology 2021;12:642400
Frontiers in pharmacology 2021;12:642400
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Tamura Y, Jee E, Kouzaki K, Kotani T, Nakazato K
Physiological reports 2021 Sep;9(17):e15014
Physiological reports 2021 Sep;9(17):e15014
Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis.
Ryuge A, Kosugi T, Maeda K, Banno R, Gou Y, Zaitsu K, Ito T, Sato Y, Hirayama A, Tsubota S, Honda T, Nakajima K, Ozaki T, Kondoh K, Takahashi K, Kato N, Ishimoto T, Soga T, Nakagawa T, Koike T, Arima H, Yuzawa Y, Minokoshi Y, Maruyama S, Kadomatsu K
JCI insight 2021 Oct 22;6(20)
JCI insight 2021 Oct 22;6(20)
Immunoreactivity and a new staining method of monocarboxylate transporter 1 located in endothelial cells of cerebral vessels of human brain in distinguishing cerebral venules from arterioles.
Cao Y, Ao DH, Ma C, Qiu WY, Zhu YC
European journal of histochemistry : EJH 2021 Oct 1;65(s1)
European journal of histochemistry : EJH 2021 Oct 1;65(s1)
Monocarboxylate transporter 1 promotes proliferation and invasion of renal cancer cells by mediating acetate transport.
Li M, Long X, Wan H, Yin M, Yang B, Zhang F, Guo X
Cell biology international 2021 Jun;45(6):1278-1287
Cell biology international 2021 Jun;45(6):1278-1287
hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling.
Xie H, Xu G, Gao Y, Yuan Z
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment.
Benyahia Z, Blackman MCNM, Hamelin L, Zampieri LX, Capeloa T, Bedin ML, Vazeille T, Schakman O, Sonveaux P
Cancers 2021 Feb 2;13(3)
Cancers 2021 Feb 2;13(3)
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Li L, Ji Y, Zhang L, Cai H, Ji Z, Gu L, Yang S
International immunopharmacology 2021 Dec;101(Pt B):108222
International immunopharmacology 2021 Dec;101(Pt B):108222
Pinocembrin attenuates hemorrhagic transformation after delayed t-PA treatment in thromboembolic stroke rats by regulating endogenous metabolites.
Kong LL, Gao L, Wang KX, Liu NN, Liu CD, Ma GD, Yang HG, Qin XM, Du GH
Acta pharmacologica Sinica 2021 Aug;42(8):1223-1234
Acta pharmacologica Sinica 2021 Aug;42(8):1223-1234
ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system.
Zhang X, Dong Y, Zhao M, Ding L, Yang X, Jing Y, Song Y, Chen S, Hu Q, Ni Y
Theranostics 2020;10(26):12044-12059
Theranostics 2020;10(26):12044-12059
Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies.
Tiemeier GL, de Koning R, Wang G, Kostidis S, Rietjens RGJ, Sol WMPJ, Dumas SJ, Giera M, van den Berg CW, Eikenboom JCJ, van den Berg BM, Carmeliet P, Rabelink TJ
Stem cells translational medicine 2020 Jul;9(7):758-772
Stem cells translational medicine 2020 Jul;9(7):758-772
Low levels of AMPK promote epithelial-mesenchymal transition in lung cancer primarily through HDAC4- and HDAC5-mediated metabolic reprogramming.
Feng S, Zhang L, Liu X, Li G, Zhang B, Wang Z, Zhang H, Ma H
Journal of cellular and molecular medicine 2020 Jul;24(14):7789-7801
Journal of cellular and molecular medicine 2020 Jul;24(14):7789-7801
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications.
Zhao Y, Li M, Yao X, Fei Y, Lin Z, Li Z, Cai K, Zhao Y, Luo Z
Cell reports 2020 Dec 8;33(10):108487
Cell reports 2020 Dec 8;33(10):108487
Acidic Stress Triggers Sodium-Coupled Bicarbonate Transport and Promotes Survival in A375 Human Melanoma Cells.
Yang OCY, Loh SH
Scientific reports 2019 May 2;9(1):6858
Scientific reports 2019 May 2;9(1):6858
Subacute ruminal acidosis suppressed the expression of MCT1 in rumen of cows.
Zhao C, Wang Y, Peng Z, Sun X, Sun G, Yuan X, Li X, Liu G
Journal of cellular physiology 2019 Jul;234(7):11734-11745
Journal of cellular physiology 2019 Jul;234(7):11734-11745
Rno-miR-425-5p targets the DLST and SLC16A1 genes to reduce liver damage caused by excessive energy mobilization under cold stress.
Lang L, Xu B, Li SZ, Guo W, Yuan J, Zang S, Chen Y, Yang HM, Lian S
Journal of animal physiology and animal nutrition 2019 Jul;103(4):1251-1262
Journal of animal physiology and animal nutrition 2019 Jul;103(4):1251-1262
Monocarboxylate transporter 1 is an independent prognostic factor in esophageal squamous cell carcinoma.
Chen X, Chen X, Liu F, Yuan Q, Zhang K, Zhou W, Guan S, Wang Y, Mi S, Cheng Y
Oncology reports 2019 Apr;41(4):2529-2539
Oncology reports 2019 Apr;41(4):2529-2539
Tumoral microvesicle-activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma.
Jiang E, Xu Z, Wang M, Yan T, Huang C, Zhou X, Liu Q, Wang L, Chen Y, Wang H, Liu K, Shao Z, Shang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5690-5703
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5690-5703
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Fan Q, Yang L, Zhang X, Ma Y, Li Y, Dong L, Zong Z, Hua X, Su D, Li H, Liu J
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.
Noble RA, Bell N, Blair H, Sikka A, Thomas H, Phillips N, Nakjang S, Miwa S, Crossland R, Rand V, Televantou D, Long A, Keun HC, Bacon CM, Bomken S, Critchlow SE, Wedge SR
Haematologica 2017 Jul;102(7):1247-1257
Haematologica 2017 Jul;102(7):1247-1257
Lanthanum damages learning and memory and suppresses astrocyte-neuron lactate shuttle in rat hippocampus.
Jin C, Gao L, Li Y, Wu S, Lu X, Yang J, Cai Y
Experimental brain research 2017 Dec;235(12):3817-3832
Experimental brain research 2017 Dec;235(12):3817-3832
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