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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- HPA003324 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA003324, RRID:AB_1856982
- Product name
- Anti-SLC16A1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SLC16A1, Gene description: solute carrier family 16 (monocarboxylate transporter), member 1, Alternative Gene Names: MCT, MCT1, Validated applications: WB, IHC, ICC, Uniprot ID: P53985, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Metabolic imaging across scales reveals distinct prostate cancer phenotypes
Native holdup (nHU) to measure binding affinities from cell extracts
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-13C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study
Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study
Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
Metabolic heterogeneity confers differences in melanoma metastatic potential
Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay
Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
Sushentsev N, Hamm G, Flint L, Birtles D, Zakirov A, Richings J, Ling S, Tan J, McLean M, Ayyappan V, Horvat Menih I, Brodie C, Miller J, Mills I, Gnanapragasam V, Warren A, Barry S, Goodwin R, Barrett T, Gallagher F
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Native holdup (nHU) to measure binding affinities from cell extracts
Zambo B, Morlet B, Negroni L, Trave G, Gogl G
Science Advances 2022;8(51)
Science Advances 2022;8(51)
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-13C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study
Zaccagna F, McLean M, Grist J, Kaggie J, Mair R, Riemer F, Woitek R, Gill A, Deen S, Daniels C, Ursprung S, Schulte R, Allinson K, Chhabra A, Laurent M, Locke M, Frary A, Hilborne S, Patterson I, Carmo B, Slough R, Wilkinson I, Basu B, Wason J, Gillard J, Matys T, Watts C, Price S, Santarius T, Graves M, Jefferies S, Brindle K, Gallagher F
Radiology: Imaging Cancer 2022;4(4)
Radiology: Imaging Cancer 2022;4(4)
Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes
Shrestha P, Whelchel A, Nicholas S, Liang W, Ma J, Karamichos D, Rasool M
Analytical Cellular Pathology 2022;2022
Analytical Cellular Pathology 2022;2022
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study
Ursprung S, Woitek R, McLean M, Priest A, Crispin-Ortuzar M, Brodie C, Gill A, Gehrung M, Beer L, Riddick A, Field-Rayner J, Grist J, Deen S, Riemer F, Kaggie J, Zaccagna F, Duarte J, Locke M, Frary A, Aho T, Armitage J, Casey R, Mendichovszky I, Welsh S, Barrett T, Graves M, Eisen T, Mitchell T, Warren A, Brindle K, Sala E, Stewart G, Gallagher F
Cancers 2022;14(2):335
Cancers 2022;14(2):335
Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer
Sushentsev N, McLean M, Warren A, Benjamin A, Brodie C, Frary A, Gill A, Jones J, Kaggie J, Lamb B, Locke M, Miller J, Mills I, Priest A, Robb F, Shah N, Schulte R, Graves M, Gnanapragasam V, Brindle K, Barrett T, Gallagher F
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
Ros S, Wright A, D'Santos P, Hu D, Hesketh R, Lubling Y, Georgopoulou D, Lerda G, Couturier D, Razavi P, Pelossof R, Batra A, Mannion E, Lewis D, Martin A, Baird R, Oliveira M, de Boo L, Linn S, Scaltriti M, Rueda O, Bruna A, Caldas C, Brindle K
Cancer Cell 2020;38(4):516-533.e9
Cancer Cell 2020;38(4):516-533.e9
Metabolic heterogeneity confers differences in melanoma metastatic potential
Tasdogan A, Faubert B, Ramesh V, Ubellacker J, Shen B, Solmonson A, Murphy M, Gu Z, Gu W, Martin M, Kasitinon S, Vandergriff T, Mathews T, Zhao Z, Schadendorf D, DeBerardinis R, Morrison S
Nature 2019;577(7788):115-120
Nature 2019;577(7788):115-120
Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay
Hashimoto M, Girardi E, Eichner R, Superti-Furga G
ACS Chemical Biology 2018;13(6):1480-1486
ACS Chemical Biology 2018;13(6):1480-1486
Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
Saini J, Corneo B, Miller J, Kiehl T, Wang Q, Boles N, Blenkinsop T, Stern J, Temple S
Cell Stem Cell 2017;20(5):635-647.e7
Cell Stem Cell 2017;20(5):635-647.e7
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and pancreas tissues using HPA003324 antibody. Corresponding SLC16A1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
