Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA003324 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA003324, RRID:AB_1856982
- Product name
- Anti-SLC16A1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SLC16A1, Gene description: solute carrier family 16 (monocarboxylate transporter), member 1, Alternative Gene Names: MCT, MCT1, Validated applications: WB, IHC, ICC, Uniprot ID: P53985, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Metabolic imaging across scales reveals distinct prostate cancer phenotypes.
Native holdup (nHU) to measure binding affinities from cell extracts
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-13C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study
Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes
Hyperpolarised (13)C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer.
Hyperpolarized (13)C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma-A Proof of Principle Study.
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
Metabolic heterogeneity confers differences in melanoma metastatic potential
Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay
Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
Sushentsev N, Hamm G, Flint L, Birtles D, Zakirov A, Richings J, Ling S, Tan JY, McLean MA, Ayyappan V, Horvat Menih I, Brodie C, Miller JL, Mills IG, Gnanapragasam VJ, Warren AY, Barry ST, Goodwin RJA, Barrett T, Gallagher FA
Nature communications 2024 Jul 16;15(1):5980
Nature communications 2024 Jul 16;15(1):5980
Native holdup (nHU) to measure binding affinities from cell extracts
Zambo B, Morlet B, Negroni L, Trave G, Gogl G
Science Advances 2022;8(51)
Science Advances 2022;8(51)
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-13C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study
Zaccagna F, McLean M, Grist J, Kaggie J, Mair R, Riemer F, Woitek R, Gill A, Deen S, Daniels C, Ursprung S, Schulte R, Allinson K, Chhabra A, Laurent M, Locke M, Frary A, Hilborne S, Patterson I, Carmo B, Slough R, Wilkinson I, Basu B, Wason J, Gillard J, Matys T, Watts C, Price S, Santarius T, Graves M, Jefferies S, Brindle K, Gallagher F
Radiology: Imaging Cancer 2022;4(4)
Radiology: Imaging Cancer 2022;4(4)
Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes
Shrestha P, Whelchel A, Nicholas S, Liang W, Ma J, Karamichos D, Rasool M
Analytical Cellular Pathology 2022;2022
Analytical Cellular Pathology 2022;2022
Hyperpolarised (13)C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer.
Sushentsev N, McLean MA, Warren AY, Benjamin AJV, Brodie C, Frary A, Gill AB, Jones J, Kaggie JD, Lamb BW, Locke MJ, Miller JL, Mills IG, Priest AN, Robb FJL, Shah N, Schulte RF, Graves MJ, Gnanapragasam VJ, Brindle KM, Barrett T, Gallagher FA
Nature communications 2022 Jan 24;13(1):466
Nature communications 2022 Jan 24;13(1):466
Hyperpolarized (13)C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma-A Proof of Principle Study.
Ursprung S, Woitek R, McLean MA, Priest AN, Crispin-Ortuzar M, Brodie CR, Gill AB, Gehrung M, Beer L, Riddick ACP, Field-Rayner J, Grist JT, Deen SS, Riemer F, Kaggie JD, Zaccagna F, Duarte JAG, Locke MJ, Frary A, Aho TF, Armitage JN, Casey R, Mendichovszky IA, Welsh SJ, Barrett T, Graves MJ, Eisen T, Mitchell TJ, Warren AY, Brindle KM, Sala E, Stewart GD, Gallagher FA
Cancers 2022 Jan 11;14(2)
Cancers 2022 Jan 11;14(2)
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
Ros S, Wright A, D'Santos P, Hu D, Hesketh R, Lubling Y, Georgopoulou D, Lerda G, Couturier D, Razavi P, Pelossof R, Batra A, Mannion E, Lewis D, Martin A, Baird R, Oliveira M, de Boo L, Linn S, Scaltriti M, Rueda O, Bruna A, Caldas C, Brindle K
Cancer Cell 2020;38(4):516-533.e9
Cancer Cell 2020;38(4):516-533.e9
Metabolic heterogeneity confers differences in melanoma metastatic potential
Tasdogan A, Faubert B, Ramesh V, Ubellacker J, Shen B, Solmonson A, Murphy M, Gu Z, Gu W, Martin M, Kasitinon S, Vandergriff T, Mathews T, Zhao Z, Schadendorf D, DeBerardinis R, Morrison S
Nature 2019;577(7788):115-120
Nature 2019;577(7788):115-120
Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay
Hashimoto M, Girardi E, Eichner R, Superti-Furga G
ACS Chemical Biology 2018;13(6):1480-1486
ACS Chemical Biology 2018;13(6):1480-1486
Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
Saini J, Corneo B, Miller J, Kiehl T, Wang Q, Boles N, Blenkinsop T, Stern J, Temple S
Cell Stem Cell 2017;20(5):635-647.e7
Cell Stem Cell 2017;20(5):635-647.e7
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and pancreas tissues using HPA003324 antibody. Corresponding SLC16A1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol