Explore
Validate
Learn
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA021451 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA021451, RRID:AB_1853663
- Product name
- Anti-SLC16A3
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SLC16A3, Gene description: solute carrier family 16 (monocarboxylate transporter), member 3, Alternative Gene Names: MCT3, MCT4, Validated applications: ICC, IHC, Uniprot ID: O15427, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin
Monocarboxylate Transporter-1 (MCT1)-Mediated Lactate Uptake Protects Pancreatic Adenocarcinoma Cells from Oxidative Stress during Glutamine Scarcity Thereby Promoting Resistance against Inhibitors of Glutamine Metabolism
mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study
Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer
Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
High expression of monocarboxylate transporter 4 (MCT 4), but not MCT 1, predicts poor prognosis in patients with non-small cell lung cancer
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
Ayyangar U, Karkhanis A, Tay H, Afandi A, Bhattacharjee O, KS L, Lee S, Chan J, Raghavan S
The EMBO Journal 2024;43(7):1113-1134
The EMBO Journal 2024;43(7):1113-1134
Monocarboxylate Transporter-1 (MCT1)-Mediated Lactate Uptake Protects Pancreatic Adenocarcinoma Cells from Oxidative Stress during Glutamine Scarcity Thereby Promoting Resistance against Inhibitors of Glutamine Metabolism
Ammar N, Hildebrandt M, Geismann C, Röder C, Gemoll T, Sebens S, Trauzold A, Schäfer H
Antioxidants 2023;12(10):1818
Antioxidants 2023;12(10):1818
mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells
Peltanová B, Holcová Polanská H, Raudenská M, Balvan J, Navrátil J, Vičar T, Gumulec J, Čechová B, Kräter M, Guck J, Kalfeřt D, Grega M, Plzák J, Betka J, Masařík M
Cancers 2022;14(9):2286
Cancers 2022;14(9):2286
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study
Ursprung S, Woitek R, McLean M, Priest A, Crispin-Ortuzar M, Brodie C, Gill A, Gehrung M, Beer L, Riddick A, Field-Rayner J, Grist J, Deen S, Riemer F, Kaggie J, Zaccagna F, Duarte J, Locke M, Frary A, Aho T, Armitage J, Casey R, Mendichovszky I, Welsh S, Barrett T, Graves M, Eisen T, Mitchell T, Warren A, Brindle K, Sala E, Stewart G, Gallagher F
Cancers 2022;14(2):335
Cancers 2022;14(2):335
Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer
Sushentsev N, McLean M, Warren A, Benjamin A, Brodie C, Frary A, Gill A, Jones J, Kaggie J, Lamb B, Locke M, Miller J, Mills I, Priest A, Robb F, Shah N, Schulte R, Graves M, Gnanapragasam V, Brindle K, Barrett T, Gallagher F
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
Heid I, Münch C, Karakaya S, Lueong S, Winkelkotte A, Liffers S, Godfrey L, Cheung P, Savvatakis K, Topping G, Englert F, Kritzner L, Grashei M, Tannapfel A, Viebahn R, Wolters H, Uhl W, Vangala D, Smeets E, Aarntzen E, Rauh D, Weichert W, Hoheisel J, Hahn S, Schilling F, Braren R, Trajkovic-Arsic M, Siveke J
Cancer & Metabolism 2022;10(1)
Cancer & Metabolism 2022;10(1)
High expression of monocarboxylate transporter 4 (MCT 4), but not MCT 1, predicts poor prognosis in patients with non-small cell lung cancer
Tong Y, Hu X, Xiang X, Fang L
Translational Cancer Research 2021;10(3):1336-1345
Translational Cancer Research 2021;10(3):1336-1345
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
Ros S, Wright A, D'Santos P, Hu D, Hesketh R, Lubling Y, Georgopoulou D, Lerda G, Couturier D, Razavi P, Pelossof R, Batra A, Mannion E, Lewis D, Martin A, Baird R, Oliveira M, de Boo L, Linn S, Scaltriti M, Rueda O, Bruna A, Caldas C, Brindle K
Cancer Cell 2020;38(4):516-533.e9
Cancer Cell 2020;38(4):516-533.e9
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
Updegraff B, Zhou X, Guo Y, Padanad M, Chen P, Yang C, Sudderth J, Rodriguez-Tirado C, Girard L, Minna J, Mishra P, DeBerardinis R, O’Donnell K
Cell Reports 2018;25(8):2223-2233.e6
Cell Reports 2018;25(8):2223-2233.e6
No comments: Submit comment
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
- Sample type
- Human
