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- References [16]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16835-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16835-1-AP, RRID:AB_1851273
- Product name
- KRT80 antibody
- Antibody type
- Polyclonal
- Description
- KRT80 antibody (Cat. #16835-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines.
KRT80 expression works as a biomarker and a target for differentiation in gastric cancer.
The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer.
Tandem mass tag (TMT) quantitative protein analysis-based proteomics and parallel reaction monitoring (PRM) validation revealed that MST4 accelerates osteosarcoma proliferation by increasing MRC2 activity.
Sequencing and Bioinformatics analysis of lncRNA/circRNA-miRNA-mRNA in Glioblastoma multiforme.
MiR-4268 suppresses gastric cancer genesis through inhibiting keratin 80.
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation.
Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis.
OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer.
The NALCN channel regulates metastasis and nonmalignant cell dissemination.
Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Keratin Profiling by Single-Cell RNA-Sequencing Identifies Human Prostate Stem Cell Lineage Hierarchy and Cancer Stem-Like Cells.
Small interfering RNA-mediated knockdown of KRT80 suppresses colorectal cancer proliferation.
Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway.
Huang S, Tong W, Yang B, Ma L, Zhang J, Wang C, Xu L, Mei J
Journal of Cancer 2024;15(8):2229-2244
Journal of Cancer 2024;15(8):2229-2244
Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines.
Ogasawara N, Kano Y, Yoneyama Y, Kobayashi S, Watanabe S, Kirino S, Velez-Bravo FD, Hong Y, Ostapiuk A, Lutsik P, Onishi I, Yamauchi S, Hiraguri Y, Ito G, Kinugasa Y, Ohashi K, Watanabe M, Okamoto R, Tejpar S, Yui S
iScience 2024 Mar 15;27(3):109247
iScience 2024 Mar 15;27(3):109247
KRT80 expression works as a biomarker and a target for differentiation in gastric cancer.
Shi KH, Xue H, Zhao EH, Xiao LJ, Sun HZ, Zheng HC
Histology and histopathology 2024 Jan;39(1):117-130
Histology and histopathology 2024 Jan;39(1):117-130
The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer.
Yun WJ, Li J, Yin NC, Zhang CY, Cui ZG, Zhang L, Zheng HC
Cancer biology & therapy 2024 Dec 31;25(1):2302162
Cancer biology & therapy 2024 Dec 31;25(1):2302162
Tandem mass tag (TMT) quantitative protein analysis-based proteomics and parallel reaction monitoring (PRM) validation revealed that MST4 accelerates osteosarcoma proliferation by increasing MRC2 activity.
Liu Y, Zhang X, Ren X, Sun J, Wen Y, Guo Z, Ma Q
Molecular carcinogenesis 2023 Sep;62(9):1338-1354
Molecular carcinogenesis 2023 Sep;62(9):1338-1354
Sequencing and Bioinformatics analysis of lncRNA/circRNA-miRNA-mRNA in Glioblastoma multiforme.
Wang R, Li Q, Chu X, Li N, Liang H, He F
Metabolic brain disease 2023 Oct;38(7):2289-2300
Metabolic brain disease 2023 Oct;38(7):2289-2300
MiR-4268 suppresses gastric cancer genesis through inhibiting keratin 80.
Zhang F, Wang G, Yan W, Jiang H
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2051-2064
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2051-2064
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation.
Kobayashi S, Ogasawara N, Watanabe S, Yoneyama Y, Kirino S, Hiraguri Y, Inoue M, Nagata S, Okamoto-Uchida Y, Kofuji S, Shimizu H, Ito G, Mizutani T, Yamauchi S, Kinugasa Y, Kano Y, Nemoto Y, Watanabe M, Tsuchiya K, Nishina H, Okamoto R, Yui S
Inflammation and regeneration 2022 Nov 28;42(1):49
Inflammation and regeneration 2022 Nov 28;42(1):49
Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis.
Dou S, Wang Q, Zhang B, Wei C, Wang H, Liu T, Duan H, Jiang H, Liu M, Qi X, Zhou Q, Xie L, Shi W, Gao H
Cell discovery 2022 Jul 12;8(1):66
Cell discovery 2022 Jul 12;8(1):66
OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer.
Ouyang S, Zeng Z, Liu Z, Zhang Z, Sun J, Wang X, Ma M, Ye X, Yu J, Kang W
Cell death discovery 2022 Feb 2;8(1):45
Cell death discovery 2022 Feb 2;8(1):45
The NALCN channel regulates metastasis and nonmalignant cell dissemination.
Rahrmann EP, Shorthouse D, Jassim A, Hu LP, Ortiz M, Mahler-Araujo B, Vogel P, Paez-Ribes M, Fatemi A, Hannon GJ, Iyer R, Blundon JA, Lourenço FC, Kay J, Nazarian RM, Hall BA, Zakharenko SS, Winton DJ, Zhu L, Gilbertson RJ
Nature genetics 2022 Dec;54(12):1827-1838
Nature genetics 2022 Dec;54(12):1827-1838
Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Arango D, Sturgill D, Yang R, Kanai T, Bauer P, Roy J, Wang Z, Hosogane M, Schiffers S, Oberdoerffer S
Molecular cell 2022 Aug 4;82(15):2797-2814.e11
Molecular cell 2022 Aug 4;82(15):2797-2814.e11
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Liu O, Wang C, Wang S, Hu Y, Gou R, Dong H, Li S, Li X, Lin B
Journal of Cancer 2021;12(22):6835-6850
Journal of Cancer 2021;12(22):6835-6850
Keratin Profiling by Single-Cell RNA-Sequencing Identifies Human Prostate Stem Cell Lineage Hierarchy and Cancer Stem-Like Cells.
Hu WY, Hu DP, Xie L, Nonn L, Lu R, Abern M, Shioda T, Prins GS
International journal of molecular sciences 2021 Jul 28;22(15)
International journal of molecular sciences 2021 Jul 28;22(15)
Small interfering RNA-mediated knockdown of KRT80 suppresses colorectal cancer proliferation.
Lin J, Fan X, Chen J, Xie X, Yu H
Experimental and therapeutic medicine 2020 Dec;20(6):176
Experimental and therapeutic medicine 2020 Dec;20(6):176
Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway.
Li C, Liu X, Liu Y, Liu X, Wang R, Liao J, Wu S, Fan J, Peng Z, Li B, Wang Z
Cell death & disease 2018 Sep 27;9(10):1009
Cell death & disease 2018 Sep 27;9(10):1009
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 16835-1-AP(KRT80 antibody) at dilution of 1:1500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 16835-1-AP(KRT80 antibody) at dilution of 1:200 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KRT80 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KRT80. This antibody recognizes human, mouse, rat antigen. The KRT80 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
