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- References [15]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 24171-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#24171-1-AP, RRID:AB_2687577
- Product name
- NEK2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NEK2 antibody (Cat. #24171-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NEK2 promotes oral squamous cell carcinoma progression and serves as a diagnostic and therapeutic target.
Zinc finger protein 695 facilitates the proliferation of colorectal cancer cells through activation of the NEK2 and PI3K/Akt/mTOR signaling pathways.
NEK2 Contributes to the Protection Against Cryptorchidism Outcomes.
KLF15 regulates macrophage polarization patterns in deep vein thrombosis.
NEK2 promotes the progression of osteosarcoma through the AKT/p-AKT pathway and interacts with FoxM1.
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
NUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix.
NEK2 is a potential pan-cancer biomarker and immunotherapy target.
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
NEK2 is associated with poor prognosis of clear cell renal cell carcinoma and promotes tumor cell growth and metastasis.
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1.
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Wu H, Huang S, Wu N, Chen W
Scientific reports 2026 Apr 10;
Scientific reports 2026 Apr 10;
Zinc finger protein 695 facilitates the proliferation of colorectal cancer cells through activation of the NEK2 and PI3K/Akt/mTOR signaling pathways.
Li X, Li X, Wang J, Xue M, Zhang M, Shuai J, Zhang J, Ding D, Wang Y, Hou S, Chi X, Sun H, Gao Q, Kang C
Oncology reports 2025 Oct;54(4)
Oncology reports 2025 Oct;54(4)
NEK2 Contributes to the Protection Against Cryptorchidism Outcomes.
Zhou X, Ye S, Wang X, Liang Z, Qian N, Ji L, Xian H, Wang Z, Ge W
Birth defects research 2025 May;117(5):e2485
Birth defects research 2025 May;117(5):e2485
KLF15 regulates macrophage polarization patterns in deep vein thrombosis.
Li J, Xiang Y, Shentu H, Yang X, Yang J, Ge W, Song E
International immunopharmacology 2025 May 16;155:114632
International immunopharmacology 2025 May 16;155:114632
NEK2 promotes the progression of osteosarcoma through the AKT/p-AKT pathway and interacts with FoxM1.
Tan X, Liang X, Feng Y, Xie M, Zhong K, Luo W, Wang Y, Yin Y, Cai Y
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):120
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):120
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Li J, Wang Y, Wei S, Xu S, Dai S, Zhang L, Tian Z, Zhao L, Lv H
Molecular carcinogenesis 2025 Feb;64(2):244-259
Molecular carcinogenesis 2025 Feb;64(2):244-259
NUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix.
Gao M, Ye P, Zhang Y, Guo Y, Xu J
Carcinogenesis 2025 Apr 3;46(2)
Carcinogenesis 2025 Apr 3;46(2)
NEK2 is a potential pan-cancer biomarker and immunotherapy target.
Zhang L, Li Y, Deng J, Liao W, Liu T, Shen F
Discover oncology 2024 Nov 7;15(1):626
Discover oncology 2024 Nov 7;15(1):626
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Zhu Y, Jian X, Chen S, An G, Jiang D, Yang Q, Zhang J, Hu J, Qiu Y, Feng X, Guo J, Chen X, Li Z, Zhou R, Hu C, He N, Shi F, Huang S, Liu H, Li X, Xie L, Zhu Y, Zhao L, Jiang Y, Li J, Wang J, Qiu L, Chen X, Jia W, He Y, Zhou W
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
Ni Z, Liu W, Pan G, Mao A, Liu J, Zhang Q, Li J, Liu L, Li H
Environmental toxicology 2023 Jul;38(7):1712-1722
Environmental toxicology 2023 Jul;38(7):1712-1722
NEK2 is associated with poor prognosis of clear cell renal cell carcinoma and promotes tumor cell growth and metastasis.
Feng X, Jiang Y, Cui Y, Xu Y, Zhang Q, Xia Q, Chen Y
Gene 2023 Jan 30;851:147040
Gene 2023 Jan 30;851:147040
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
Peng Y, Zhang Y, Luo M, Pan Y, Zhou R, Yan YN, Yi T, Luo F, Wang B, Wang L, Ran C, Wang H
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Bai R, Yuan C, Sun W, Zhang J, Luo Y, Gao Y, Li Y, Gong Y, Xie C
International journal of biological sciences 2021;17(8):1995-2008
International journal of biological sciences 2021;17(8):1995-2008
NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1.
Zhang X, Huang X, Xu J, Li E, Lao M, Tang T, Zhang G, Guo C, Zhang X, Chen W, Yadav DK, Bai X, Liang T
Nature communications 2021 Jul 27;12(1):4536
Nature communications 2021 Jul 27;12(1):4536
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y, Shi Q
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Current biology : CB 2017 May 22;27(10):1498-1505.e6
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 24171-1-AP(NEK2 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NEK2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human NEK2. This antibody recognizes human, mouse, rat antigen. The NEK2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
