Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 24171-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#24171-1-AP, RRID:AB_2687577
- Product name
- NEK2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NEK2 antibody (Cat. #24171-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
NEK2 is associated with poor prognosis of clear cell renal cell carcinoma and promotes tumor cell growth and metastasis.
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1.
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Zhu Y, Jian X, Chen S, An G, Jiang D, Yang Q, Zhang J, Hu J, Qiu Y, Feng X, Guo J, Chen X, Li Z, Zhou R, Hu C, He N, Shi F, Huang S, Liu H, Li X, Xie L, Zhu Y, Zhao L, Jiang Y, Li J, Wang J, Qiu L, Chen X, Jia W, He Y, Zhou W
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
Ni Z, Liu W, Pan G, Mao A, Liu J, Zhang Q, Li J, Liu L, Li H
Environmental toxicology 2023 Jul;38(7):1712-1722
Environmental toxicology 2023 Jul;38(7):1712-1722
NEK2 is associated with poor prognosis of clear cell renal cell carcinoma and promotes tumor cell growth and metastasis.
Feng X, Jiang Y, Cui Y, Xu Y, Zhang Q, Xia Q, Chen Y
Gene 2023 Jan 30;851:147040
Gene 2023 Jan 30;851:147040
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
Peng Y, Zhang Y, Luo M, Pan Y, Zhou R, Yan YN, Yi T, Luo F, Wang B, Wang L, Ran C, Wang H
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Bai R, Yuan C, Sun W, Zhang J, Luo Y, Gao Y, Li Y, Gong Y, Xie C
International journal of biological sciences 2021;17(8):1995-2008
International journal of biological sciences 2021;17(8):1995-2008
NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1.
Zhang X, Huang X, Xu J, Li E, Lao M, Tang T, Zhang G, Guo C, Zhang X, Chen W, Yadav DK, Bai X, Liang T
Nature communications 2021 Jul 27;12(1):4536
Nature communications 2021 Jul 27;12(1):4536
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y, Shi Q
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Current biology : CB 2017 May 22;27(10):1498-1505.e6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 24171-1-AP(NEK2 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NEK2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human NEK2. This antibody recognizes human, mouse, rat antigen. The NEK2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.