Antibody data
- Antibody Data
- Antigen structure
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- Product number
- A01606 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-NEK2 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for NEK2 detection. Host: Rabbit.Size: 100μg. Tested applications: WB. Reactive species: Human. NEK2 information: Molecular Weight: 51763 MW; Subcellular Localization: Isoform 1: Nucleus. Nucleus, nucleolus . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole. Chromosome, centromere, kinetochore. Chromosome, centromere . STK3/MST2 and SAV1 are required for its targeting to the centrosome. Colocalizes with SGO1 and MAD1L1 at the kinetochore. Not associated with kinetochore in the interphase but becomes associated with it upon the breakdown of the nuclear envelope. Has a nucleolar targeting/ retention activity via a coiled-coil domain at the C-terminal end; Tissue Specificity: Isoform 1 and isoform 2 are expressed in peripheral blood T-cells and a wide variety of transformed cell types. Isoform 1 and isoform 4 are expressed in the testis. Up- regulated in various cancer cell lines, as well as primary breast tumors.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg
- Concentration
- 1.0 mg/mL by UV absorbance at 280 nm
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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