Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- MB0063 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CBX5 monoclonal antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length Human CBX5.
- Description
- Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members (Ï«, ÉÇ, and ÎÛ) are primarily associated with centromeric heterochromatin; however, HP1ÉÇ and ÎÛ also localize to euchromatic sites in the genome. HP1 proteins are approximately 25 kDa in size and contain a conserved amino-terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain. The chromodomain facilitates binding to histone H3 tri-methylated at Lys9, a histone "mark" closely associated with centromeric heterochromatin.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot detection of CBX5 in MCF7, 293T, HelaNE, 3T3, C6, COS7&Mouse brain lysates and using CBX5 antibody (1:1000 diluted) .