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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN116939 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 301-312) antibody
- Antibody type
- Polyclonal
- Antigen
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 301-312 of PDK-1 (genome data base accession number AC005591).
- Description
- Immunoaffinity chromatography.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
Peptide sequence: R-K-I-Q-E-V-W-R-Q
-R-Y-Q-S- Epitope
- AA 301-312
- Vial size
- 0.1 mg
- Concentration
- 1.3 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references In search for the troponin of the kidney.
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B.
Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells.
Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.
High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site.
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity.
Noppert SJ, Mayer G
Current medicinal chemistry 2009;16(32):4219-29
Current medicinal chemistry 2009;16(32):4219-29
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B.
Scheid MP, Marignani PA, Woodgett JR
Molecular and cellular biology 2002 Sep;22(17):6247-60
Molecular and cellular biology 2002 Sep;22(17):6247-60
Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells.
Wick MJ, Wick KR, Chen H, He H, Dong LQ, Quon MJ, Liu F
The Journal of biological chemistry 2002 May 10;277(19):16632-8
The Journal of biological chemistry 2002 May 10;277(19):16632-8
Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.
Fujita N, Sato S, Ishida A, Tsuruo T
The Journal of biological chemistry 2002 Mar 22;277(12):10346-53
The Journal of biological chemistry 2002 Mar 22;277(12):10346-53
High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site.
Biondi RM, Komander D, Thomas CC, Lizcano JM, Deak M, Alessi DR, van Aalten DM
The EMBO journal 2002 Aug 15;21(16):4219-28
The EMBO journal 2002 Aug 15;21(16):4219-28
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity.
Park J, Hill MM, Hess D, Brazil DP, Hofsteenge J, Hemmings BA
The Journal of biological chemistry 2001 Oct 5;276(40):37459-71
The Journal of biological chemistry 2001 Oct 5;276(40):37459-71
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