Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- NB100-2383 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-2383, RRID:AB_10003289
- Product name
- Rabbit Polyclonal Pyruvate Dehydrogenase Kinase 1/PDK1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.42 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Enhanced aerobic glycolysis of nasopharyngeal carcinoma cells by Epstein-Barr virus latent membrane protein 1.
The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1-PKB/Akt signalling.
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
Sung WW, Chen PR, Liao MH, Lee JW
Experimental cell research 2017 Oct 1;359(1):94-100
Experimental cell research 2017 Oct 1;359(1):94-100
The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1-PKB/Akt signalling.
Tsoi H, Li L, Chen ZS, Lau KF, Tsui SK, Chan HY
The Biochemical journal 2014 Dec 15;464(3):439-47
The Biochemical journal 2014 Dec 15;464(3):439-47
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
Luo W, Chang R, Zhong J, Pandey A, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 4;109(49):E3367-76
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 4;109(49):E3367-76
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
Luo W, Hu H, Chang R, Zhong J, Knabel M, O'Meally R, Cole RN, Pandey A, Semenza GL
Cell 2011 May 27;145(5):732-44
Cell 2011 May 27;145(5):732-44
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PDK-1 Antibody [NB100-2383] - Analysis of HeLa lysates using NB100-2383. Image courtesy of Gregg Semenza - publication number 21620138 (PMID).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PDK-1 Antibody [NB100-2383] - Detection of PDK-1 in human heart lysate using NB 100-2383 at 2 ug/ml.