ABIN966815

antibody from antibodies-online

Targeting: PDK1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966815

Provider

antibodies-online

Product name

anti-Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) (pSer241) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human PDK1 around the phosphorylation site of serine 241 (A-N-SP-F-V).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer241

Vial size

100 μg

Concentration

100ug/100ul

Storage

-20°C

References

Submitted references

Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation.

Scheid MP, Parsons M, Woodgett JR
Molecular and cellular biology 2005 Mar;25(6):2347-63

---

Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function.

Lim MA, Kikani CK, Wick MJ, Dong LQ
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):14006-11

---

Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.

Sato S, Fujita N, Tsuruo T
The Journal of biological chemistry 2002 Oct 18;277(42):39360-7

---

Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism.

Chen H, Nystrom FH, Dong LQ, Li Y, Song S, Liu F, Quon MJ
Biochemistry 2001 Oct 2;40(39):11851-9