AF-351-NA
antibody from Novus Biologicals
Targeting: CXCL12
PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AF-351-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal CXCL12/SDF-1 beta Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human CXCL12/SDF-1 beta in direct ELISAs and Western blots. Neutralizes 60-80% of the biological activity of CXCL12/SDF-1 beta and does not neutralize the biological activity of SDF-1 alpha . In Western blots, less than 5% cross-reactivity with recombinant human SDF-1 alpha is observed.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.
Kenig S, Alonso MB, Mueller MM, Lah TT
Cancer letters 2010 Mar 1;289(1):53-61
Cancer letters 2010 Mar 1;289(1):53-61
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Chemotaxis Induced by CXCL12/SDF-1ß and Neutral-ization by Human CXCL12/ SDF-1ß Antibody. Chemotaxis Induced by CXCL12/SDF-1ß and Neutral-ization by Human CXCL12/ SDF-1ß Antibody.