A00053-2
antibody from Boster Biological Technology
Targeting: CXCL12
PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1
Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- A00053-2 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-CXCL12 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Rabbit IgG polyclonal antibody for CXCL12 detection. Tested with WB, IHC-P, Direct ELISA in Human;Mouse;Rat.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references The CXCR4-AT1 axis plays a vital role in glomerular injury via mediating the crosstalk between podocyte and mesangial cell.
Collagen content and C-X-C motif chemokine ligand 12 expression in neoplastic breast stroma.
MGF E peptide improves anterior cruciate ligament repair by inhibiting hypoxia-induced cell apoptosis and accelerating angiogenesis.
Angelica sinensis Polysaccharides Ameliorate Stress-Induced Premature Senescence of Hematopoietic Cell via Protecting Bone Marrow Stromal Cells from Oxidative Injuries Caused by 5-Fluorouracil.
Matrix elasticity-modified scaffold loaded with SDF-1α improves the in situ regeneration of segmental bone defect in rabbit radius.
Role of SDF-1/CXCR4 and cytokines in the development of ovary injury in chemotherapy drug induced premature ovarian failure mice.
Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells.
Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats.
Effect of ermiao fang with xixin (herba asari mandshurici) on bone marrow stem cell directional homing to a focal zone in an osteoarthritis rat model.
Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF‑1α expression in vivo.
Mesenchymal stem cell transplantation enhancement in myocardial infarction rat model under ultrasound combined with nitric oxide microbubbles.
Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer.
CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma.
SDF-1/CXCR4-mediated migration of transplanted bone marrow stromal cells toward areas of heart myocardial infarction through activation of PI3K/Akt.
Interaction of SDF-1alpha and CXCR4 plays an important role in pulmonary cellular infiltration in differentiation syndrome.
Estrogen-replacement therapy promotes angiogenesis after acute myocardial infarction by enhancing SDF-1 and estrogen receptor expression.
Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer.
SDF-1alpha/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model.
Selective tropism of liver stem cells to hepatocellular carcinoma in vivo.
Wu Q, Zhou S, Xu D, Meng P, Chen Q, Wang X, Li X, Chen S, Ye H, Ye W, Xiong Y, Li J, Miao J, Shen W, Lin X, Hou FF, Liu Y, Zhang Y, Zhou L
Translational research : the journal of laboratory and clinical medicine 2024 Feb;264:15-32
Translational research : the journal of laboratory and clinical medicine 2024 Feb;264:15-32
Collagen content and C-X-C motif chemokine ligand 12 expression in neoplastic breast stroma.
Ferreira CJDS, Caires IQS, Costa Neto WJBD, Almeida SMV
Revista da Associacao Medica Brasileira (1992) 2023;69(9):e20221210
Revista da Associacao Medica Brasileira (1992) 2023;69(9):e20221210
MGF E peptide improves anterior cruciate ligament repair by inhibiting hypoxia-induced cell apoptosis and accelerating angiogenesis.
Sha Y, Yang L, Lv Y
Journal of cellular physiology 2019 Jun;234(6):8846-8861
Journal of cellular physiology 2019 Jun;234(6):8846-8861
Angelica sinensis Polysaccharides Ameliorate Stress-Induced Premature Senescence of Hematopoietic Cell via Protecting Bone Marrow Stromal Cells from Oxidative Injuries Caused by 5-Fluorouracil.
Xiao H, Xiong L, Song X, Jin P, Chen L, Chen X, Yao H, Wang Y, Wang L
International journal of molecular sciences 2017 Oct 28;18(11)
International journal of molecular sciences 2017 Oct 28;18(11)
Matrix elasticity-modified scaffold loaded with SDF-1α improves the in situ regeneration of segmental bone defect in rabbit radius.
Chen G, Lv Y
Scientific reports 2017 May 10;7(1):1672
Scientific reports 2017 May 10;7(1):1672
Role of SDF-1/CXCR4 and cytokines in the development of ovary injury in chemotherapy drug induced premature ovarian failure mice.
Luo Q, Yin N, Zhang L, Yuan W, Zhao W, Luan X, Zhang H
Life sciences 2017 Jun 15;179:103-109
Life sciences 2017 Jun 15;179:103-109
Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells.
Zheng K, Wu W, Yang S, Huang L, Chen J, Gong C, Fu Z, Lin R, Tan J
Experimental and therapeutic medicine 2016 Jun;11(6):2425-2431
Experimental and therapeutic medicine 2016 Jun;11(6):2425-2431
Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats.
Wu S, Li L, Wang G, Shen W, Xu Y, Liu Z, Zhuo Z, Xia H, Gao Y, Tan K
International journal of nanomedicine 2014;9:5639-51
International journal of nanomedicine 2014;9:5639-51
Effect of ermiao fang with xixin (herba asari mandshurici) on bone marrow stem cell directional homing to a focal zone in an osteoarthritis rat model.
Xu Y, Dai G, Liu Q, Zhu H, Chen W, Zhang P, Zhao T, Lin N
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2014 Aug;34(4):477-87
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2014 Aug;34(4):477-87
Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF‑1α expression in vivo.
Zhu H, Sun Q, Tan C, Xu M, Dai Z, Wang Z, Fan J, Zhou J
Molecular medicine reports 2014 Aug;10(2):585-92
Molecular medicine reports 2014 Aug;10(2):585-92
Mesenchymal stem cell transplantation enhancement in myocardial infarction rat model under ultrasound combined with nitric oxide microbubbles.
Tong J, Ding J, Shen X, Chen L, Bian Y, Ma G, Yao Y, Yang F
PloS one 2013;8(11):e80186
PloS one 2013;8(11):e80186
Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer.
Ma L, Qiao H, He C, Yang Q, Cheung CH, Kanwar JR, Sun X
Investigational new drugs 2012 Apr;30(2):508-17
Investigational new drugs 2012 Apr;30(2):508-17
CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma.
Zhao BC, Wang ZJ, Mao WZ, Ma HC, Han JG, Zhao B, Xu HM
World journal of gastroenterology 2011 May 21;17(19):2389-96
World journal of gastroenterology 2011 May 21;17(19):2389-96
SDF-1/CXCR4-mediated migration of transplanted bone marrow stromal cells toward areas of heart myocardial infarction through activation of PI3K/Akt.
Yu J, Li M, Qu Z, Yan D, Li D, Ruan Q
Journal of cardiovascular pharmacology 2010 May;55(5):496-505
Journal of cardiovascular pharmacology 2010 May;55(5):496-505
Interaction of SDF-1alpha and CXCR4 plays an important role in pulmonary cellular infiltration in differentiation syndrome.
Zhou J, Hu L, Cui Z, Jiang X, Wang G, Krissansen GW, Sun X
International journal of hematology 2010 Mar;91(2):293-302
International journal of hematology 2010 Mar;91(2):293-302
Estrogen-replacement therapy promotes angiogenesis after acute myocardial infarction by enhancing SDF-1 and estrogen receptor expression.
Chen Y, Jin X, Zeng Z, Liu W, Wang B, Wang H
Microvascular research 2009 Mar;77(2):71-7
Microvascular research 2009 Mar;77(2):71-7
Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer.
Zhang S, Qi L, Li M, Zhang D, Xu S, Wang N, Sun B
Journal of experimental & clinical cancer research : CR 2008 Nov 4;27(1):62
Journal of experimental & clinical cancer research : CR 2008 Nov 4;27(1):62
SDF-1alpha/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model.
Wang Y, Deng Y, Zhou GQ
Brain research 2008 Feb 21;1195:104-12
Brain research 2008 Feb 21;1195:104-12
Selective tropism of liver stem cells to hepatocellular carcinoma in vivo.
Zhong XG, He S, Yin W, Deng JY, Cheng B
World journal of gastroenterology 2007 Jul 28;13(28):3886-91
World journal of gastroenterology 2007 Jul 28;13(28):3886-91
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- IHC analysis of CXCL12 using anti-CXCL12 antibody (A00053-2).CXCL12 was detected in paraffin-embedded section of human endometrial carcinoma tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/ml rabbit anti-CXCL12 Antibody (A00053-2) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
- Additional image