Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 24613-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Angiopoietin 2 antibody
- Antibody type
- Polyclonal
- Description
- Angiopoietin 2 antibody (Cat. #24613-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphodiesterase inhibitor ameliorates senescent changes of renal interstitial pericytes in aging kidney.
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Human placenta-based genome-wide mRNA sequencing to identify TEK/IGF1/CSF1/ANGPT2 as crucial segments in the pathogenesis of pre-eclampsia.
Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy.
Metabotropic glutamate receptor 5 blockade attenuates pathological cardiac remodelling in pulmonary arterial hypertension.
Single-cell sequencing reveals microglia induced angiogenesis by specific subsets of endothelial cells following spinal cord injury.
Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway.
MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF-1α and ANGPT2.
Lycium barbarum polysaccharides attenuates high glucose-induced diabetic retinal angiogenesis by rescuing the expression of miR-15a-5p in RF/6A cells.
Akt1-dependent expression of angiopoietin 1 and 2 in vascular smooth muscle cells leads to vascular stabilization.
A study of the effects of hydroxyapatite bioceramic extract on Ang/Tie2 system of umbilical vein endothelial cells.
MAPK-RAP1A Signaling Enriched in Hepatocellular Carcinoma Is Associated With Favorable Tumor-Infiltrating Immune Cells and Clinical Prognosis.
Discovery of Novel Small-Molecule Antiangiogenesis Agents to Treat Diabetic Retinopathy.
The Changes of Twist1 Pathway in Pulmonary Microvascular Permeability in a Newborn Rat Model of Hyperoxia-Induced Acute Lung Injury.
Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma.
Targeting the ERβ/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC.
Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.
Angiopoietin-2 regulated by progesterone induces uterine vascular remodeling during pregnancy.
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Diosmetin inhibits tumor development and block tumor angiogenesis in skin cancer.
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
Chloroquine inhibits tumor growth and angiogenesis in malignant pleural effusion.
Kim HD, Kim EN, Lim JH, Kim Y, Ban TH, Lee H, Kim YS, Park CW, Choi BS
Aging cell 2024 Mar;23(3):e14075
Aging cell 2024 Mar;23(3):e14075
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB
Nature communications 2023 Oct 18;14(1):6582
Nature communications 2023 Oct 18;14(1):6582
Human placenta-based genome-wide mRNA sequencing to identify TEK/IGF1/CSF1/ANGPT2 as crucial segments in the pathogenesis of pre-eclampsia.
Wang L, Zhang L, Fan Y, Peng Y, Song D, Fu J, Wang X
Frontiers in genetics 2022;13:944932
Frontiers in genetics 2022;13:944932
Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy.
Ma Q, Beal JR, Song X, Bhurke A, Bagchi IC, Bagchi MK
Endocrinology 2022 Oct 23;163(12)
Endocrinology 2022 Oct 23;163(12)
Metabotropic glutamate receptor 5 blockade attenuates pathological cardiac remodelling in pulmonary arterial hypertension.
Mprah R, Ma Y, Adzika GK, Ndzie Noah ML, Adekunle AO, Duah M, Adu-Amankwaah J, Wowui PI, Okwuma JD, Qiao W, Wang C
Clinical and experimental pharmacology & physiology 2022 May;49(5):558-566
Clinical and experimental pharmacology & physiology 2022 May;49(5):558-566
Single-cell sequencing reveals microglia induced angiogenesis by specific subsets of endothelial cells following spinal cord injury.
Yao C, Cao Y, Wang D, Lv Y, Liu Y, Gu X, Wang Y, Wang X, Yu B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22393
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22393
Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway.
Ao L, Gao H, Jia L, Liu S, Guo J, Liu B, Dong Q
Molecular immunology 2022 Jan;141:13-20
Molecular immunology 2022 Jan;141:13-20
MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF-1α and ANGPT2.
Huang YH, Lian WS, Wang FS, Wang PW, Lin HY, Tsai MC, Yang YL
International journal of molecular sciences 2022 Jan 31;23(3)
International journal of molecular sciences 2022 Jan 31;23(3)
Lycium barbarum polysaccharides attenuates high glucose-induced diabetic retinal angiogenesis by rescuing the expression of miR-15a-5p in RF/6A cells.
Zhu Y, Zhao Q, Jiang Y
Journal of ethnopharmacology 2022 Jan 30;283:114652
Journal of ethnopharmacology 2022 Jan 30;283:114652
Akt1-dependent expression of angiopoietin 1 and 2 in vascular smooth muscle cells leads to vascular stabilization.
Ha JM, Jin SY, Lee HS, Kum HJ, Vafaeinik F, Ha HK, Song SH, Kim CD, Bae SS
Experimental & molecular medicine 2022 Aug;54(8):1133-1145
Experimental & molecular medicine 2022 Aug;54(8):1133-1145
A study of the effects of hydroxyapatite bioceramic extract on Ang/Tie2 system of umbilical vein endothelial cells.
Zhang X, Liu Y, Su Y, Fan X, Hu F
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):531-538
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):531-538
MAPK-RAP1A Signaling Enriched in Hepatocellular Carcinoma Is Associated With Favorable Tumor-Infiltrating Immune Cells and Clinical Prognosis.
Li H, Han G, Li X, Li B, Wu B, Jin H, Wu L, Wang W
Frontiers in oncology 2021;11:649980
Frontiers in oncology 2021;11:649980
Discovery of Novel Small-Molecule Antiangiogenesis Agents to Treat Diabetic Retinopathy.
Kim D, Choi SW, Cho J, Been JH, Choi K, Jiang W, Han J, Oh J, Park C, Choi S, Seo S, Kim KL, Suh W, Lee SK, Kim S
Journal of medicinal chemistry 2021 May 13;64(9):5535-5550
Journal of medicinal chemistry 2021 May 13;64(9):5535-5550
The Changes of Twist1 Pathway in Pulmonary Microvascular Permeability in a Newborn Rat Model of Hyperoxia-Induced Acute Lung Injury.
Ruan Y, Dong W, Kang L, Lei X, Zhang R, Wang F, Zhu X
Frontiers in pediatrics 2020;8:190
Frontiers in pediatrics 2020;8:190
Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma.
Qin S, Yi M, Jiao D, Li A, Wu K
Journal of Cancer 2020;11(1):153-167
Journal of Cancer 2020;11(1):153-167
Targeting the ERβ/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC.
Gu J, Zhang Y, Han Z, Gao L, Cui J, Sun Y, Niu Y, You B, Huang CP, Chang C, Wang X, Yeh S
Cell death & disease 2020 May 14;11(5):367
Cell death & disease 2020 May 14;11(5):367
Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.
Wang Y, Lu J, Chen L, Bian H, Hu J, Li D, Xia C, Xu H
Molecular therapy. Nucleic acids 2020 Jun 5;20:421-437
Molecular therapy. Nucleic acids 2020 Jun 5;20:421-437
Angiopoietin-2 regulated by progesterone induces uterine vascular remodeling during pregnancy.
Park YG, Choi J, Seol JW
Molecular medicine reports 2020 Aug;22(2):1235-1242
Molecular medicine reports 2020 Aug;22(2):1235-1242
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Bi Y, Guo S, Xu X, Kong P, Cui H, Yan T, Ma Y, Cheng Y, Chen Y, Liu X, Zhang L, Cheng C, Xu E, Qian Y, Yang J, Song B, Li H, Wang F, Hu X, Liu X, Niu X, Zhai Y, Liu J, Li Y, Cheng X, Cui Y
Cell death & disease 2020 Apr 27;11(4):296
Cell death & disease 2020 Apr 27;11(4):296
Diosmetin inhibits tumor development and block tumor angiogenesis in skin cancer.
Choi J, Lee DH, Park SY, Seol JW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109091
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109091
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
Zhou PT, Wang LP, Qu MJ, Shen H, Zheng HR, Deng LD, Ma YY, Wang YY, Wang YT, Tang YH, Tian HL, Zhang ZJ, Yang GY
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
Chloroquine inhibits tumor growth and angiogenesis in malignant pleural effusion.
Li Q, Yuan DM, Ma LH, Ma CH, Liu YF, Lv TF, Song Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct 22;
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct 22;
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 24613-1-AP( ANGPT2 Antibody) at dilution of 1:600
- Other comments
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 24613-1-AP( ANGPT2 Antibody) at dilution of 1:50 (under 40x lens)
- Other comments
- IHC