abx105138

antibody from Abbexa

Targeting: ANGPT2 Ang2

ELISA (Recommended by provider)

Antibody Data

Product number

abx105138

Provider

Abbexa

Product name

Angiopoietin 2 Antibody (Biotin)

Antibody type

Polyclonal

Description

Angiopoietin-2 Antibody (Biotin) is a Rabbit Polyclonal antibody against Angiopoietin-2 conjugated to Biotin. Angiopoietin-2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Reactivity

Mouse

Host

Rabbit

Conjugate

Biotin

Isotype

IgG