Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- Ab088801 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- ANGPT2 Antibody
- Antibody type
- Polyclonal
- Description
- Rabbit anti Human ANGPT2 Antibody, Polyclonal antibody, could be used for WB, IHC and so on.ApplicationWB: 0.2-2µg/mLIHC: 5-20µg/mLProtein FunctionCan induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
AA 24-165
- Vial size
- 100_l,10_l,1ml,20_l,50_l
- Concentration
- Lot by Lot
- Storage
- Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- ANGPT2 Antibody (Ab088801) - Western Blot All lanes: ANGPT2 Antibody (Ab088801) at 1/5000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution Predicted band size: 79 kDa Observed band size: 73 kDa Exposure time: 0.8 s
Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- ANGPT2 Antibody (Ab088801) - IHC DAB staining on IHC Samples: Human Placenta Tissue Primary Ab: 20 μg/mL ANGPT2 Antibody (Ab088801) Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.