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- Antigen structure
- References [23]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10156-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10156-2-AP, RRID:AB_2252532
- Product name
- PPARD antibody
- Antibody type
- Polyclonal
- Description
- PPARD antibody (Cat. #10156-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Herpetrione, a New Type of PPARα Ligand as a Therapeutic Strategy Against Nonalcoholic Steatohepatitis.
Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2.
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
Data of RNA-seq transcriptomes of liver, bone, heart, kidney and blood in klotho mice at a pre-symptomatic state and the effect of a traditional Japanese multi-herbal medicine, juzentaihoto.
Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway.
Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms.
Combined application of geranylgeranylacetone and amelogenin promotes angiogenesis and wound healing in human periodontal ligament cells.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
Tissue-Specific Splicing and Dietary Interaction of a Mutant As160 Allele Determine Muscle Metabolic Fitness in Rodents.
Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
The chromatin remodeler SRCAP promotes self-renewal of intestinal stem cells.
Oleic acid up-regulates myosin heavy chain (MyHC) 1 expression and increases mitochondrial mass and maximum respiration in C2C12 myoblasts.
Effects of PPARs/20-HETE on the renal impairment under diabetic conditions.
Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy.
High Fat Diet Suppresses Peroxisome Proliferator-Activated Receptors and Reduces Dopaminergic Neurons in the Substantia Nigra.
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1.
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a.
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
Dihydrocapsaicin Attenuates Plaque Formation through a PPARγ/LXRα Pathway in apoE(-/-) Mice Fed a High-Fat/High-Cholesterol Diet.
Linghu L, Zong W, Liao Y, Chen Q, Meng F, Wang G, Liao Z, Lan X, Chen M
Research (Washington, D.C.) 2023;6:0276
Research (Washington, D.C.) 2023;6:0276
Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2.
Wang S, Zhou Y, Yu R, Ling J, Li B, Yang C, Cheng Z, Qian R, Lin Z, Yu C, Zheng J, Zheng X, Jia Q, Wu W, Wu Q, Chen M, Yuan S, Dong W, Shi Y, Jansen R, Yang C, Hao Y, Yao M, Qin W, Jin H
JHEP reports : innovation in hepatology 2023 Oct;5(10):100843
JHEP reports : innovation in hepatology 2023 Oct;5(10):100843
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Ji J, Li S, Jiang Z, Yu J, Sun Y, Cai Z, Dong Y, Sun X
International journal of molecular sciences 2022 Sep 16;23(18)
International journal of molecular sciences 2022 Sep 16;23(18)
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
Yu Z, Xie X, Su X, Lv H, Song S, Liu C, You Y, Tian M, Zhu L, Wang L, Qi J, Zhu Q
Cellular signalling 2022 May;93:110304
Cellular signalling 2022 May;93:110304
Data of RNA-seq transcriptomes of liver, bone, heart, kidney and blood in klotho mice at a pre-symptomatic state and the effect of a traditional Japanese multi-herbal medicine, juzentaihoto.
Okada N, Oshima K, Iwasaki Y, Maruko A, Matsumura K, Iioka E, Vu TD, Fujitsuka N, Nishi A, Sugiyama A, Nishiyama M, Kaneko A, Mizoguchi K, Yamamoto M, Nishimura S
Data in brief 2022 Jun;42:108197
Data in brief 2022 Jun;42:108197
Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway.
Han W, Wang N, Kong R, Bao W, Lu J
Journal of translational medicine 2022 Feb 12;20(1):86
Journal of translational medicine 2022 Feb 12;20(1):86
Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms.
Liu K, Zhao X, Qi X, Hou DL, Li HB, Gu YH, Xu QL
European journal of medicinal chemistry 2021 Jun 5;218:113388
European journal of medicinal chemistry 2021 Jun 5;218:113388
Combined application of geranylgeranylacetone and amelogenin promotes angiogenesis and wound healing in human periodontal ligament cells.
Yamato H, Sanui T, Yotsumoto K, Nakao Y, Watanabe Y, Hayashi C, Aihara R, Iwashita M, Tanaka U, Taketomi T, Fukuda T, Nishimura F
Journal of cellular biochemistry 2021 Jul;122(7):716-730
Journal of cellular biochemistry 2021 Jul;122(7):716-730
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
Wang Y, Lan W, Xu M, Song J, Mao J, Li C, Du X, Jiang Y, Li E, Zhang R, Wang Q
Cell death & disease 2021 Feb 26;12(2):214
Cell death & disease 2021 Feb 26;12(2):214
Tissue-Specific Splicing and Dietary Interaction of a Mutant As160 Allele Determine Muscle Metabolic Fitness in Rodents.
Yang X, Chen Q, Ouyang Q, Rong P, Feng W, Quan C, Li M, Jiang Q, Liang H, Zhao TJ, Wang HY, Chen S
Diabetes 2021 Aug;70(8):1826-1842
Diabetes 2021 Aug;70(8):1826-1842
Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.
Okada N, Oshima K, Iwasaki Y, Maruko A, Matsumura K, Iioka E, Vu TD, Fujitsuka N, Nishi A, Sugiyama A, Nishiyama M, Kaneko A, Mizoguchi K, Yamamoto M, Nishimura S
Gene 2021 Aug 20;794:145752
Gene 2021 Aug 20;794:145752
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
Tong F, Mao X, Zhang S, Xie H, Yan B, Wang B, Sun J, Wei L
Cancer letters 2020 May 28;478:34-44
Cancer letters 2020 May 28;478:34-44
The chromatin remodeler SRCAP promotes self-renewal of intestinal stem cells.
Ye B, Yang L, Qian G, Liu B, Zhu X, Zhu P, Ma J, Xie W, Li H, Lu T, Wang Y, Wang S, Du Y, Wang Z, Jiang J, Li J, Fan D, Meng S, Wu J, Tian Y, Fan Z
The EMBO journal 2020 Jul 1;39(13):e103786
The EMBO journal 2020 Jul 1;39(13):e103786
Oleic acid up-regulates myosin heavy chain (MyHC) 1 expression and increases mitochondrial mass and maximum respiration in C2C12 myoblasts.
Watanabe N, Komiya Y, Sato Y, Watanabe Y, Suzuki T, Arihara K
Biochemical and biophysical research communications 2020 Apr 30;525(2):406-411
Biochemical and biophysical research communications 2020 Apr 30;525(2):406-411
Effects of PPARs/20-HETE on the renal impairment under diabetic conditions.
Ding S, Huang J, Qiu H, Chen R, Zhang J, Huang B, Cheng O, Jiang Q
Experimental cell research 2019 Sep 1;382(1):111455
Experimental cell research 2019 Sep 1;382(1):111455
Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy.
Ding S, Qiu H, Huang J, Chen R, Zhang J, Huang B, Zou X, Cheng O, Jiang Q
Chemico-biological interactions 2019 Jul 1;307:116-124
Chemico-biological interactions 2019 Jul 1;307:116-124
High Fat Diet Suppresses Peroxisome Proliferator-Activated Receptors and Reduces Dopaminergic Neurons in the Substantia Nigra.
Kao YC, Wei WY, Tsai KJ, Wang LC
International journal of molecular sciences 2019 Dec 27;21(1)
International journal of molecular sciences 2019 Dec 27;21(1)
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
Zhang J, Qiu H, Huang J, Ding S, Huang B, Wu Q, Jiang Q
Biochemical and biophysical research communications 2018 Jul 7;502(1):55-61
Biochemical and biophysical research communications 2018 Jul 7;502(1):55-61
Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1.
Zhang Y, Gao L, Cheng Z, Cai J, Niu Y, Meng W, Zhao Q
Neurotoxicity research 2017 Feb;31(2):259-268
Neurotoxicity research 2017 Feb;31(2):259-268
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a.
Ji J, Zeng XN, Cao LL, Zhang L, Zhao Z, Yang DD, Sun XL
Neuropharmacology 2017 Feb;113(Pt A):396-406
Neuropharmacology 2017 Feb;113(Pt A):396-406
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
Du P, Ma Q, Zhu ZD, Li G, Wang Y, Li QQ, Chen YF, Shang ZZ, Zhang J, Zhao L
European journal of pharmacology 2016 Dec 15;793:119-126
European journal of pharmacology 2016 Dec 15;793:119-126
Dihydrocapsaicin Attenuates Plaque Formation through a PPARγ/LXRα Pathway in apoE(-/-) Mice Fed a High-Fat/High-Cholesterol Diet.
Hu YW, Ma X, Huang JL, Mao XR, Yang JY, Zhao JY, Li SF, Qiu YR, Yang J, Zheng L, Wang Q
PloS one 2013;8(6):e66876
PloS one 2013;8(6):e66876
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 10156-2-AP(PPARD antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PPARD antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PPARD. This antibody recognizes human, mouse, rat antigen. The PPARD antibody has been validated for the following applications: ELISA, WB, IHC analysis.
