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- Product number
- 60193-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60193-1-Ig, RRID:AB_10896827
- Product name
- PPARD antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated PPARD antibody (Cat. #60193-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1B10E1
- Vial size
- 20ul, 150ul
Submitted references Metformin suppresses PPARδ-driven CD47 transcription to enhance macrophage phagocytosis in lung cancer.
The TRIB1-PPARγ Axis Regulates Cholesterol Metabolism in Pancreatic Ductal Adenocarcinoma.
MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway.
Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway.
Isoimperatorin Reduces Synovial Inflammation and Fibrosis in Knee Osteoarthritis via the cAMP Signalling Pathway.
Neonatal sevoflurane exposure disrupted fatty acids metabolism, leading to hypomyelination and neurological impairments.
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
The Splice Variant of the NCOR2 Gene BQ323636.1 Modulates ACSL4 Expression to Enhance Fatty Acid Metabolism and Support of Tumor Growth in Breast Cancer.
Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis.
Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction.
Axin formation inhibitor 1 aggravates hepatic ischemia‒reperfusion injury by promoting the ubiquitination and degradation of PPARβ.
Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota.
Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress.
The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-β catenin-p300 Interactions in Hepatocellular Carcinoma.
A tau fragment links depressive-like behaviors and cognitive declines in Alzheimer's disease mouse models through attenuating mitochondrial function.
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
PPARβ/δ activation protects against hepatic ischaemia-reperfusion injury.
A proteomics landscape of circadian clock in mouse liver.
Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice.
Cui Q, Wang H, Yu H, Li Y, Wang Y, Shi J, Hou Y
The Journal of biological chemistry 2026 Mar;302(3):111159
The Journal of biological chemistry 2026 Mar;302(3):111159
The TRIB1-PPARγ Axis Regulates Cholesterol Metabolism in Pancreatic Ductal Adenocarcinoma.
Sun R, Qin H, Zhang W, Guo X, Teng Y, Xu M, Liu J, Ning Z, Wang A
Annals of the New York Academy of Sciences 2026 Mar;1557(1):e70224
Annals of the New York Academy of Sciences 2026 Mar;1557(1):e70224
MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway.
Shang H, Yang S, Sun M, Zhao Y, Guo R, Wang W, Qian B, Li Y, Hu M, Bian X, Cao Q, Li C, Fan B, Li B
PLoS pathogens 2026 Apr;22(4):e1014170
PLoS pathogens 2026 Apr;22(4):e1014170
Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway.
Qiu J, Fu L, Xue Y, Yang Y, Qiao F, Zhu W, Gao Y, Fang M, Liu Y, Gao Z, Guan Y, Gao Y, Zhang X, Shang Z
Frontiers in pharmacology 2025;16:1563561
Frontiers in pharmacology 2025;16:1563561
Isoimperatorin Reduces Synovial Inflammation and Fibrosis in Knee Osteoarthritis via the cAMP Signalling Pathway.
Jie L, Liu J, Zhu Z, Huang Z, Liu Y, Liu G, Shen X, Li Y, Shi X
Journal of cellular and molecular medicine 2025 Oct;29(19):e70880
Journal of cellular and molecular medicine 2025 Oct;29(19):e70880
Neonatal sevoflurane exposure disrupted fatty acids metabolism, leading to hypomyelination and neurological impairments.
Jiang S, Cao T, Li J, Di L, Wang X, Xie Z, Huang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Oct;191:118495
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Oct;191:118495
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Wang J, Du J, Song Y, Tan X, Wu J, Wang T, Shi Y, Xu X, Yu Z, Song B
Cell death & disease 2025 May 9;16(1):371
Cell death & disease 2025 May 9;16(1):371
The Splice Variant of the NCOR2 Gene BQ323636.1 Modulates ACSL4 Expression to Enhance Fatty Acid Metabolism and Support of Tumor Growth in Breast Cancer.
Tsoi H, You CP, Cheung KH, Tse YS, Khoo US
International journal of molecular sciences 2025 May 22;26(11)
International journal of molecular sciences 2025 May 22;26(11)
Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis.
Wang G, Dong Y, Qiao X, Jia C, Wang J, Chen G, Zheng K, Jiang C, Li X
Kidney diseases (Basel, Switzerland) 2025 Jan-Dec;11(1):450-468
Kidney diseases (Basel, Switzerland) 2025 Jan-Dec;11(1):450-468
Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction.
Qu X, Yang P, Jiao L, Yin Y
Frontiers in bioscience (Landmark edition) 2025 Jan 20;30(1):25565
Frontiers in bioscience (Landmark edition) 2025 Jan 20;30(1):25565
Axin formation inhibitor 1 aggravates hepatic ischemia‒reperfusion injury by promoting the ubiquitination and degradation of PPARβ.
Qian B, Yin B, Yu H, Wang C, Lu S, Ke S, Li Z, Li X, Hua Y, Li Z, Zhou Y, Meng Z, Fu Y, Tang W, Ma Y
Nature communications 2025 Feb 19;16(1):1776
Nature communications 2025 Feb 19;16(1):1776
Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota.
Wei X, Liang J, Liu J, Dai Y, Leng X, Cheng Y, Chi L
Journal of ethnopharmacology 2024 May 23;326:117995
Journal of ethnopharmacology 2024 May 23;326:117995
Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress.
Khan A, Khan B, Hussain S, Wang Y, Mai W, Hou Y
Aquatic toxicology (Amsterdam, Netherlands) 2024 Aug;273:107021
Aquatic toxicology (Amsterdam, Netherlands) 2024 Aug;273:107021
The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-β catenin-p300 Interactions in Hepatocellular Carcinoma.
Leung YK, Lee SG, Wang J, Guruvaiah P, Rusch NJ, Ho SM, Park C, Kim K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2308539
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2308539
A tau fragment links depressive-like behaviors and cognitive declines in Alzheimer's disease mouse models through attenuating mitochondrial function.
Wang Y, Wang J, Chen H, Li X, Xu R, Gao F, Yu H, Li F, Qin D, Wang J, Shi Y, Li Y, Liu S, Zhang X, Ding S, Hu Y, Huang L, Gao XY, Lu Z, Luo J, Wang ZH
Frontiers in aging neuroscience 2023;15:1293164
Frontiers in aging neuroscience 2023;15:1293164
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
Zhang H, Xia P, Yang Z, Liu J, Zhu Y, Huang Z, Zhang Z, Yuan Y
Clinical and translational medicine 2023 Oct;13(10):e1443
Clinical and translational medicine 2023 Oct;13(10):e1443
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
PPARβ/δ activation protects against hepatic ischaemia-reperfusion injury.
Qian B, Wang C, Li X, Ma P, Dong L, Shen B, Wu H, Li N, Kang K, Ma Y
Liver international : official journal of the International Association for the Study of the Liver 2023 Dec;43(12):2808-2823
Liver international : official journal of the International Association for the Study of the Liver 2023 Dec;43(12):2808-2823
A proteomics landscape of circadian clock in mouse liver.
Wang Y, Song L, Liu M, Ge R, Zhou Q, Liu W, Li R, Qie J, Zhen B, Wang Y, He F, Qin J, Ding C
Nature communications 2018 Apr 19;9(1):1553
Nature communications 2018 Apr 19;9(1):1553
Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice.
Charrier A, Wang L, Stephenson EJ, Ghanta SV, Ko CW, Croniger CM, Bridges D, Buchner DA
American journal of physiology. Endocrinology and metabolism 2016 Nov 1;311(5):E869-E880
American journal of physiology. Endocrinology and metabolism 2016 Nov 1;311(5):E869-E880
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PPARD antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human PPARD. This antibody recognizes human, mouse antigen. The PPARD antibody has been validated for the following applications: ELISA, WB analysis.
