Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B1759 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-IRF7 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Mouse Interferon regulatory factor 7 or IRF-7 (UniProt P70434) is encoded by the murine irf7 gene (Entrez Gene ID 54123). IFN-ÎÛ-induced gene activations are mediated by both signal transducers and activators of transcription (STATs) and interferon regulatory factors (IRFs). STAT1 dimer, for example, stimulates immediate transcription by binding IFN-ÎÛ-activated site (GAS) sequence in the promoter region of target genes. While a delayed, secondary transcription activation is observed among IFN-ÎÛ target genes containing an IFN regulatory factors (IRF) binding site within the interferon-stimulated response element (ISRE) sequence. Irf7 transcription is shown to be activated by STAT1 and IRF9 in response to type II interferon (IFN) IFN-ÎÛ stimulation in MEF cultures. The expressed IRF7 protein then further cooperates with STAT1 and IRF1 to stimulate the expression of a subset of IFN-ÎÛ-induced STAT1 target genes.
- Reactivity
- Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 _L
- Concentration
- Please refer to lot specific datasheet.
- Storage
- Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
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