14255-1-AP

antibody from Proteintech Group

Targeting: NCAM1 CD56, NCAM

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

14255-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#14255-1-AP, RRID:AB_2149421

Product name

NCAM1/CD56 antibody

Antibody type

Polyclonal

Description

KD/KO validated NCAM1/CD56 antibody (Cat. #14255-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells.

Wang Z, Li X, Yang J, Gong Y, Zhang H, Qiu X, Liu Y, Zhou C, Chen Y, Greenbaum J, Cheng L, Hu Y, Xie J, Yang X, Li Y, Schiller MR, Chen Y, Tan L, Tang SY, Shen H, Xiao HM, Deng HW
International journal of biological sciences 2021;17(15):4192-4206

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Decreased IL-6 and NK Cells in Early-Stage Lung Adenocarcinoma Presenting as Ground-Glass Opacity.

Zhang P, He B, Cai Q, Tu G, Peng X, Zhao Z, Peng W, Yu F, Wang M, Tao Y, Wang X
Frontiers in oncology 2021;11:705888

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Clinical and Molecular Characterizations of Papillary Thyroid Cancer in Children and Young Adults: A Multicenter Retrospective Study.

Guo K, Qian K, Shi Y, Sun T, Chen L, Mei D, Dong K, Gu S, Liu J, Lv Z, Wang Z
Thyroid : official journal of the American Thyroid Association 2021 Nov;31(11):1693-1706

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Construction of a single nucleotide variant score-related gene-based prognostic model in hepatocellular carcinoma: analysis of multi-independent databases and validation in vitro.

Xu YJ, He MK, Liu S, Huang LC, Bu XY, Kan A, Shi M
Cancer cell international 2021 Nov 18;21(1):610

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Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma.

Yang B, Su Z, Chen G, Zeng Z, Tan J, Wu G, Zhu S, Lin L
Oncology letters 2021 Mar;21(3):180

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Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2.

Liu Q, Pang J, Wang LA, Huang Z, Xu J, Yang X, Xie Q, Huang Y, Tang T, Tong D, Liu G, Wang L, Zhang D, Ma Q, Xiao H, Lan W, Qin J, Jiang J
The Journal of pathology 2021 Jan;253(1):106-118

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The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation.

Abid K, Popovic MB, Bourloud KB, Schoumans J, Grand-Guillaume J, Grouzmann E, Mühlethaler-Mottet A
Oncotarget 2021 Jan 5;12(1):49-60

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Verification of pain-related neuromodulation mechanisms of icariin in knee osteoarthritis.

Li X, Xu Y, Li H, Jia L, Wang J, Liang S, Cai A, Tan X, Wang L, Wang X, Huang Y, Tao E, Ye H, Asakawa T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112259

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Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity.

Lim WF, Forouhan M, Roberts TC, Dabney J, Ellerington R, Speciale AA, Manzano R, Lieto M, Sangha G, Banerjee S, Conceição M, Cravo L, Biscans A, Roux L, Pourshafie N, Grunseich C, Duguez S, Khvorova A, Pennuto M, Cortes CJ, La Spada AR, Fischbeck KH, Wood MJA, Rinaldi C
Science advances 2021 Aug;7(34)

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sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.

Wu S, Zhang X, Dong M, Yang Z, Zhang M, Chen Q
Oncology reports 2020 Oct;44(4):1467-1478

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Thioredoxin activity confers resistance against oxidative stress in tumor-infiltrating NK cells.

Yang Y, Neo SY, Chen Z, Cui W, Chen Y, Guo M, Wang Y, Xu H, Kurzay A, Alici E, Holmgren L, Haglund F, Wang K, Lundqvist A
The Journal of clinical investigation 2020 Oct 1;130(10):5508-5522

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A novel chimeric PD1-NKG2D-41BB receptor enhances antitumor activity of NK92 cells against human lung cancer H1299 cells by triggering pyroptosis.

Lu C, Guo C, Chen H, Zhang H, Zhi L, Lv T, Li M, Niu Z, Lu P, Zhu W
Molecular immunology 2020 May 6;122:200-206

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Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice.

Nishina S, Yamauchi A, Kawaguchi T, Kaku K, Goto M, Sasaki K, Hara Y, Tomiyama Y, Kuribayashi F, Torimura T, Hino K
Cellular and molecular gastroenterology and hepatology 2019;7(1):115-134

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Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity.

Mustafa T, Li Q, Kelly LE, Gibbon A, Ryan I, Roffey K, Simonds S, Cowley MA, Sleeman MW
PloS one 2019;14(4):e0214621

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Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.

Wang YJ, Traum D, Schug J, Gao L, Liu C, HPAP Consortium., Atkinson MA, Powers AC, Feldman MD, Naji A, Chang KM, Kaestner KH
Cell metabolism 2019 Mar 5;29(3):769-783.e4

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Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.

Ma H, Yang W, Zhang L, Liu S, Zhao M, Zhou G, Wang L, Jin S, Zhang Z, Hu J
British journal of cancer 2019 Feb;120(3):317-330

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Fluoride Induces Autoimmune Orchitis Involved with Enhanced IL-17A Secretion in Mice Testis.

Wu P, Sun Z, Lv X, Pei X, Manthari RK, Wang J
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13333-13343

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Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration.

Liu Q, Tong D, Liu G, Gao J, Wang LA, Xu J, Yang X, Xie Q, Huang Y, Pang J, Wang L, He Y, Zhang D, Ma Q, Lan W, Jiang J
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Nov 15;24(22):5622-5634

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Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

Badders NM, Korff A, Miranda HC, Vuppala PK, Smith RB, Winborn BJ, Quemin ER, Sopher BL, Dearman J, Messing J, Kim NC, Moore J, Freibaum BD, Kanagaraj AP, Fan B, Tillman H, Chen PC, Wang Y, Freeman BB III, Li Y, Kim HJ, La Spada AR, Taylor JP
Nature medicine 2018 May;24(4):427-437

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Mechanism and prognostic value of indoleamine 2,3-dioxygenase 1 expressed in hepatocellular carcinoma.

Li S, Han X, Lyu N, Xie Q, Deng H, Mu L, Pan T, Huang X, Wang X, Shi Y, Zhao M
Cancer science 2018 Dec;109(12):3726-3736

---

Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis.

Lee FHF, Zhang H, Jiang A, Zai CC, Liu F
Scientific reports 2018 Aug 27;8(1):12856

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TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.

Ackermann MA, Petrosino JM, Manring HR, Wright P, Shettigar V, Kilic A, Janssen PML, Ziolo MT, Accornero F
Journal of molecular and cellular cardiology 2017 Nov;112:49-57

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PloS one 2016;11(8):e0158827

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Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice.

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PloS one 2016;11(8):e0157311

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Elderly mouse skeletal muscle fibres have a diminished capacity to upregulate NCAM production in response to denervation.

Gillon A, Sheard P
Biogerontology 2015 Dec;16(6):811-23

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Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.

Tsuchiya A, Lu WY, Weinhold B, Boulter L, Stutchfield BM, Williams MJ, Guest RV, Minnis-Lyons SE, MacKinnon AC, Schwarzer D, Ichida T, Nomoto M, Aoyagi Y, Gerardy-Schahn R, Forbes SJ
Hepatology (Baltimore, Md.) 2014 Nov;60(5):1727-40

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Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells.

Montavon G, Jauquier N, Coulon A, Peuchmaur M, Flahaut M, Bourloud KB, Yan P, Delattre O, Sommer L, Joseph JM, Janoueix-Lerosey I, Gross N, Mühlethaler-Mottet A
Oncotarget 2014 Jun 30;5(12):4452-66

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse brain tissue were subjected to SDS PAGE followed by western blot with 14255-1-AP(NCAM1 antibody) at dilution of 1:300

Sample type

tissue

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human colon using 14255-1-AP(NCAM1 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human colon using 14255-1-AP(NCAM1 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue

Flow cytometry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The NCAM1/CD56 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NCAM1/CD56. This antibody recognizes human,mouse,rat antigen. The NCAM1/CD56 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.

Appendix

14255-1-AP.pdf

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