Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations [0]
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- Product number
- 14-0567-80 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-CD56 (NCAM) Monoclonal Antibody (CMSSB), eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: This CMSSB monoclonal antibody reacts with human CD56, also known as Neural Cell Adhesion Molecule (NCAM). CD56 is a highly glycosylated transmembrane molecule expressed by neurons and plays a role in the homotypic adhesion of neural cells. In the hematopoietic system, CD56 is expressed on NK cells and a subset of T cells referred to as NKT cells. Staining with CMSSB does not block binding of MEM188 or CB56. Applications Reported: This CMSSB antibody has been reported for use in flow cytometric analysis and immunohistology staining of paraffin embedded tissue sections. Applications Tested: This CMSSB antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1.0 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- CMSSB
- Vial size
- 25 µg
- Concentration
- 0.5 mg/mL
- Storage
- 4° C
Submitted references Interaction and Mutual Activation of Different Innate Immune Cells Is Necessary to Kill and Clear Hepatitis C Virus-Infected Cells.
Functional dichotomy of Vδ2 γδ T cells in chronic hepatitis C virus infections: role in cytotoxicity but not for IFN-γ production.
Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins.
Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation.
Higher Frequency of NK and CD4+ T-Cells in Mucosa and Potent Cytotoxic Response in HIV Controllers.
Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma.
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.
Interferon-gamma promoter hypomethylation and increased expression in chronic periodontitis.
Functional subsets of mouse natural killer cells.
Klöss V, Grünvogel O, Wabnitz G, Eigenbrod T, Ehrhardt S, Lasitschka F, Lohmann V, Dalpke AH
Frontiers in immunology 2017;8:1238
Frontiers in immunology 2017;8:1238
Functional dichotomy of Vδ2 γδ T cells in chronic hepatitis C virus infections: role in cytotoxicity but not for IFN-γ production.
Yin W, Tong S, Zhang Q, Shao J, Liu Q, Peng H, Hu H, Peng M, Hu P, Ren H, Tian Z, Zhang D
Scientific reports 2016 May 19;6:26296
Scientific reports 2016 May 19;6:26296
Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins.
Soh KT, Tario JD Jr, Colligan S, Maguire O, Pan D, Minderman H, Wallace PK
Current protocols in cytometry 2016 Jan 6;75:7.45.1-7.45.33
Current protocols in cytometry 2016 Jan 6;75:7.45.1-7.45.33
Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation.
Bhanu NV, Sidoli S, Garcia BA
Proteomics 2016 Feb;16(3):448-58
Proteomics 2016 Feb;16(3):448-58
Higher Frequency of NK and CD4+ T-Cells in Mucosa and Potent Cytotoxic Response in HIV Controllers.
Taborda NA, González SM, Alvarez CM, Correa LA, Montoya CJ, Rugeles MT
PloS one 2015;10(8):e0136292
PloS one 2015;10(8):e0136292
Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma.
Barnig C, Cernadas M, Dutile S, Liu X, Perrella MA, Kazani S, Wechsler ME, Israel E, Levy BD
Science translational medicine 2013 Feb 27;5(174):174ra26
Science translational medicine 2013 Feb 27;5(174):174ra26
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.
Sonnenberg GF, Monticelli LA, Alenghat T, Fung TC, Hutnick NA, Kunisawa J, Shibata N, Grunberg S, Sinha R, Zahm AM, Tardif MR, Sathaliyawala T, Kubota M, Farber DL, Collman RG, Shaked A, Fouser LA, Weiner DB, Tessier PA, Friedman JR, Kiyono H, Bushman FD, Chang KM, Artis D
Science (New York, N.Y.) 2012 Jun 8;336(6086):1321-5
Science (New York, N.Y.) 2012 Jun 8;336(6086):1321-5
Interferon-gamma promoter hypomethylation and increased expression in chronic periodontitis.
Zhang S, Crivello A, Offenbacher S, Moretti A, Paquette DW, Barros SP
Journal of clinical periodontology 2010 Nov;37(11):953-61
Journal of clinical periodontology 2010 Nov;37(11):953-61
Functional subsets of mouse natural killer cells.
Hayakawa Y, Huntington ND, Nutt SL, Smyth MJ
Immunological reviews 2006 Dec;214:47-55
Immunological reviews 2006 Dec;214:47-55
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