21609-1-AP

antibody from Proteintech Group

Targeting: IL1RAPL1 IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

21609-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#21609-1-AP, RRID:AB_10888632

Product name

IL-1-RAPL-1 antibody

Antibody type

Polyclonal

Description

KD/KO validated IL-1-RAPL-1 antibody (Cat. #21609-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay.

Cho H, Abshire ET, Popp MW, Pröschel C, Schwartz JL, Yeo GW, Maquat LE
Molecular cell 2022 Aug 4;82(15):2779-2796.e10

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Skewed inflammation is associated with aberrant interleukin-37 signaling pathway in atopic dermatitis.

Hou T, Tsang MS, Chu IM, Kan LL, Hon KL, Leung TF, Lam CW, Wong CK
Allergy 2021 Jul;76(7):2102-2114

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Splice-dependent trans-synaptic PTPδ-IL1RAPL1 interaction regulates synapse formation and non-REM sleep.

Park H, Choi Y, Jung H, Kim S, Lee S, Han H, Kweon H, Kang S, Sim WS, Koopmans F, Yang E, Kim H, Smit AB, Bae YC, Kim E
The EMBO journal 2020 Jun 2;39(11):e104150

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IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells.

Han Y, Mora J, Huard A, da Silva P, Wiechmann S, Putyrski M, Schuster C, Elwakeel E, Lang G, Scholz A, Scholz T, Schmid T, de Bruin N, Billuart P, Sala C, Burkhardt H, Parnham MJ, Ernst A, Brüne B, Weigert A
Cell reports 2019 Apr 16;27(3):835-846.e5

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IL-37 isoform D downregulates pro-inflammatory cytokines expression in a Smad3-dependent manner.

Zhao M, Li Y, Guo C, Wang L, Chu H, Zhu F, Li Y, Wang X, Wang Q, Zhao W, Shi Y, Chen W, Zhang L
Cell death & disease 2018 May 22;9(6):582

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The X-Linked Intellectual Disability Protein IL1RAPL1 Regulates Dendrite Complexity.

Montani C, Ramos-Brossier M, Ponzoni L, Gritti L, Cwetsch AW, Braida D, Saillour Y, Terragni B, Mantegazza M, Sala M, Verpelli C, Billuart P, Sala C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Jul 12;37(28):6606-6627

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human brain tissue were subjected to SDS PAGE followed by western blot with 21609-1-AP(IL1RAPL1 antibody) at dilution of 1:500

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using IL1RAPL1 antibody 21609-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human heart using 21609-1-AP(IL1RAPL1 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human heart using 21609-1-AP(IL1RAPL1 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue