Antibody data
- Antibody Data
- Antigen structure
- References [35]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 18942-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18942-1-AP, RRID:AB_2202206
- Product name
- TGF Beta 3 antibody
- Antibody type
- Polyclonal
- Description
- TGF Beta 3 antibody (Cat. #18942-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transforming growth factor-β3 attenuates septic cardiomyopathy by reversing cardiomyocyte metabolic reprogramming through Smad7 signaling.
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis.
C-X-C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8(+) T cells within the tumor microenvironment.
Solute carrier family 9 member A5 regulated by TGF-β is necessary for dental enamel formation.
2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism.
Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice.
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis.
Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing.
TGF-β3 promotes vascular normalization of prostate cancer to potentiate immunotherapy and chemotherapy.
Transforming growth factor-β3/Smad2/Smad3 signaling pathway inhibition and autophagy by the Yunpi-Xiefei-Huatan decoction ameliorated airway inflammation and mucus hypersecretion in asthmatic rats.
Exploring the toxicological network of bleomycin-induced pulmonary fibrosis: The role of long non-coding RNAs.
Involvement of Integrin β3 O-Glycosylation in Human Cytomegalovirus Internalization Into Fibroblasts.
The deubiquitinase YOD1 suppresses tumor progression by stabilizing ZNF24 in clear cell renal carcinoma.
Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups.
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
HUC-MSCs combined with platelet lysate treat diabetic chronic cutaneous ulcers in Bama miniature pig.
Targeting the long non-coding RNA MIAT for the treatment of fibroids in an animal model.
Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy.
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
Versatile Hydrogel Dressings That Dynamically Regulate the Healing of Infected Deep Burn Wounds.
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma.
Identification of polyunsaturated fatty acids related key modules and genes in metabolic dysfunction-associated fatty liver disease using WGCNA analysis.
Upregulation of key genes Eln and Tgfb3 were associated with the severity of cardiac hypertrophy.
Matrilin3/TGFβ3 gelatin microparticles promote chondrogenesis, prevent hypertrophy, and induce paracrine release in MSC spheroid for disc regeneration.
Dithiocarbazate-Copper Complexes for Bioimaging and Treatment of Pancreatic Cancer.
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis.
The regulation of CIRBP by transforming growth factor beta during heat shock-induced testicular injury.
Targeting YOD1 by RNA Interference Inhibits Proliferation and Migration of Human Oral Keratinocytes through Transforming Growth Factor-β3 Signaling Pathway.
Overexpression of YOD1 Promotes the Migration of Human Oral Keratinocytes by Enhancing TGF-β3 Signaling.
Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes.
Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells.
Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling.
CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-β3 function.
Transforming growth factor beta 3 involved in the pathogenesis of synovial chondromatosis of temporomandibular joint.
SIX1 promotes tumor lymphangiogenesis by coordinating TGFβ signals that increase expression of VEGF-C.
Zhang H, Xu J, Xu B, Shang X
Molecular and cellular biochemistry 2026 Mar;481(3):1241-1250
Molecular and cellular biochemistry 2026 Mar;481(3):1241-1250
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis.
Bhamidipati K, McIntyre ABR, Kazerounian S, Ce G, Wong SW, Tran M, Prell SA, Lau R, Khedgikar V, Altmann C, Small A, Madhu R, Presti SR, Anufrieva KS, Blazar PE, Lange JK, Seifert JA, Accelerating Medicines Partnership RA/SLE Network, Accelerating Medicines Partnership: Autoimmune and Immune-Mediated Diseases Network (AMP-AIM), Colorado Interdisciplinary Joint Biology Program (CUIJBP) Consortium, Moreland LW, Croft AP, Smith MH, Donlin LT, Lewis MJ, Jonsson AH, Pitzalis C, Thomas R, Gravallese EM, Brenner MB, Korsunsky I, Wechalekar MD, Wei K
Nature immunology 2026 Mar;27(3):556-571
Nature immunology 2026 Mar;27(3):556-571
C-X-C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8(+) T cells within the tumor microenvironment.
Tsuruta A, Fujimoto M, Hiraoka Y, Taniguchi A, Shiiba Y, Inoki T, Yamauchi T, Yoshida Y, Matsunaga N, Ohdo S, Koyanagi S
International journal of cancer 2026 Mar 15;158(6):1740-1754
International journal of cancer 2026 Mar 15;158(6):1740-1754
Solute carrier family 9 member A5 regulated by TGF-β is necessary for dental enamel formation.
Takano H, Chiba-Ohkuma R, Kobayashi S, Yamamoto R, Kataoka R, Miyakawa Y, Asada Y, Yamakoshi Y
Journal of oral biosciences 2026 Feb;68(1):100719
Journal of oral biosciences 2026 Feb;68(1):100719
2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism.
He Y, Hoa Pham TT, Xu J, Hong S, Wang J, Zhai H, Tao Q, Li R, Zhang G, Shi X
Frontiers in pharmacology 2025;16:1581138
Frontiers in pharmacology 2025;16:1581138
Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice.
Shen R, Xia P, Guo Y, Ji P, Yuan X, Wang L, Shuang S, Zhou L, Tong R, Zhang L, Liu D, Wang D
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126200
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126200
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis.
Bhamidipati K, McIntyre ABR, Kazerounian S, Ce G, Tran M, Prell SA, Lau R, Khedgikar V, Altmann C, Small A, Wong V, Madhu R, Presti S, Anufrieva KS, Blazar PE, Lange JK, Seifert J, Accelerating Medicines Partnership: RA/SLE Network, Accelerating Medicines Partnership: Autoimmune and Immune-Mediated Diseases Network (AMP-AIM), Moreland LW, Croft AP, Lewis MJ, Thomas R, Jonsson AH, Pitzalis C, Gravallese EM, Brenner MB, Korsunsky I, Wechalekar MD, Wei K
bioRxiv : the preprint server for biology 2025 Mar 17;
bioRxiv : the preprint server for biology 2025 Mar 17;
Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing.
Fu Y, Xie JL, Zhang XL, Xie GM, Zhang XM, Han YT, Xu MM, Zhang J, Zhang J
Journal of nanobiotechnology 2025 Jul 14;23(1):506
Journal of nanobiotechnology 2025 Jul 14;23(1):506
TGF-β3 promotes vascular normalization of prostate cancer to potentiate immunotherapy and chemotherapy.
Teng Q, Wang N, Lei H, Tong T, Guan Y, Huang M, Cao F, Xu B, Yang J, Huo Y, Chen W, Bi R, Wang X, Wang Z, Tian FY, Zhao B, Pang J
Cancer immunology, immunotherapy : CII 2025 Jul 12;74(8):268
Cancer immunology, immunotherapy : CII 2025 Jul 12;74(8):268
Transforming growth factor-β3/Smad2/Smad3 signaling pathway inhibition and autophagy by the Yunpi-Xiefei-Huatan decoction ameliorated airway inflammation and mucus hypersecretion in asthmatic rats.
Wang W, Chen Z, Cui K, Chen N, Gao Q
Journal of ethnopharmacology 2025 Jan 13;339:119125
Journal of ethnopharmacology 2025 Jan 13;339:119125
Exploring the toxicological network of bleomycin-induced pulmonary fibrosis: The role of long non-coding RNAs.
Li B, Shi H, Ma Y, Zhao R, Zhang H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Dec;206:115723
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Dec;206:115723
Involvement of Integrin β3 O-Glycosylation in Human Cytomegalovirus Internalization Into Fibroblasts.
Zheng L, Pan T, Wang H, Tian J, He Z
Journal of medical virology 2025 Aug;97(8):e70536
Journal of medical virology 2025 Aug;97(8):e70536
The deubiquitinase YOD1 suppresses tumor progression by stabilizing ZNF24 in clear cell renal carcinoma.
Liu J, Lu Y, Zhu R, Xi P, Yang Z, Zhang Z, Xiong Y, Liu Y, Zhu Q, Sun T, Xie W, Gong B
Cell death & disease 2025 Apr 24;16(1):334
Cell death & disease 2025 Apr 24;16(1):334
Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups.
Ji S, Cao L, Gao J, Du Y, Ye Z, Lou X, Liu F, Zhang Y, Xu J, Shi X, Wang H, Li P, Li Y, Chen H, Yang Z, Gao S, Zhang W, Huang D, Ni S, Wei M, Wang F, Wang Y, Ding T, Jing D, Fan G, Gong Z, Lu R, Qin Y, Chen J, Xu X, Wang P, Zhang B, Ding L, Robles AI, Rodriguez H, Chang DK, Hruban RH, Gao D, Gao D, Jin G, Zhou H, Wu J, Yu X
Cancer cell 2025 Apr 14;43(4):776-796.e14
Cancer cell 2025 Apr 14;43(4):776-796.e14
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
Hu YW, Wang YH, Yang F, Liu DX, Lu GH, Li ST, Wei ZX, Shen X, Jiang ZD, Zhao YF, Pang Q, Song BY, Shi ZW, Shafique S, Zhou K, Chen XL, Su WM, Jian JW, Tang KQ, Liu TL, Zhu YB
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
HUC-MSCs combined with platelet lysate treat diabetic chronic cutaneous ulcers in Bama miniature pig.
Gao Y, Chen L, Li Y, Sun S, Ran X
Regenerative therapy 2024 Jun;26:1138-1149
Regenerative therapy 2024 Jun;26:1138-1149
Targeting the long non-coding RNA MIAT for the treatment of fibroids in an animal model.
Chuang TD, Ton N, Manrique N, Rysling S, Khorram O
Clinical science (London, England : 1979) 2024 Jun 19;138(12):699-709
Clinical science (London, England : 1979) 2024 Jun 19;138(12):699-709
Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy.
Wang L, Wu L, Zhu Z, Zhang Q, Li W, Gonzalez GM, Wang Y, Rana TM
The EMBO journal 2023 Jan 16;42(2):e111673
The EMBO journal 2023 Jan 16;42(2):e111673
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
Tong MQ, Lu CT, Huang LT, Yang JJ, Yang ST, Chen HB, Xue PP, Luo LZ, Yao Q, Xu HL, Zhao YZ
Acta biomaterialia 2023 Feb;157:467-486
Acta biomaterialia 2023 Feb;157:467-486
Versatile Hydrogel Dressings That Dynamically Regulate the Healing of Infected Deep Burn Wounds.
Wang S, Wu S, Yang Y, Zhang J, Wang Y, Zhang R, Yang L
Advanced healthcare materials 2023 Dec;12(30):e2301224
Advanced healthcare materials 2023 Dec;12(30):e2301224
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma.
Khan M, Lin J, Wang B, Chen C, Huang Z, Tian Y, Yuan Y, Bu J
Frontiers in immunology 2022;13:968165
Frontiers in immunology 2022;13:968165
Identification of polyunsaturated fatty acids related key modules and genes in metabolic dysfunction-associated fatty liver disease using WGCNA analysis.
Xiao C, Chen S, Yang C, Liu J, Yu M
Frontiers in genetics 2022;13:951224
Frontiers in genetics 2022;13:951224
Upregulation of key genes Eln and Tgfb3 were associated with the severity of cardiac hypertrophy.
Zhang R, Xu X, Chen X, Hao C, Ji Z, Zuo P, Yang M, Ma G, Li Y
BMC genomics 2022 Aug 14;23(1):592
BMC genomics 2022 Aug 14;23(1):592
Matrilin3/TGFβ3 gelatin microparticles promote chondrogenesis, prevent hypertrophy, and induce paracrine release in MSC spheroid for disc regeneration.
Bello AB, Kim Y, Park S, Muttigi MS, Kim J, Park H, Lee S
NPJ Regenerative medicine 2021 Sep 3;6(1):50
NPJ Regenerative medicine 2021 Sep 3;6(1):50
Dithiocarbazate-Copper Complexes for Bioimaging and Treatment of Pancreatic Cancer.
Gou Y, Chen M, Li S, Deng J, Li J, Fang G, Yang F, Huang G
Journal of medicinal chemistry 2021 May 13;64(9):5485-5499
Journal of medicinal chemistry 2021 May 13;64(9):5485-5499
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis.
Song C, Zhou C
Journal of experimental & clinical cancer research : CR 2021 Feb 9;40(1):62
Journal of experimental & clinical cancer research : CR 2021 Feb 9;40(1):62
The regulation of CIRBP by transforming growth factor beta during heat shock-induced testicular injury.
Rao M, Ke D, Cheng G, Hu S, Wu Y, Wang Y, Zhou F, Liu H, Zhu C, Xia W
Andrology 2019 Mar;7(2):244-250
Andrology 2019 Mar;7(2):244-250
Targeting YOD1 by RNA Interference Inhibits Proliferation and Migration of Human Oral Keratinocytes through Transforming Growth Factor-β3 Signaling Pathway.
Zhou XL, Chen G, Li MX, Wang HX, Hong JW, Shen JY, Wang Q, Ge X, Ding Z, Xu LC
BioMed research international 2018;2018:6254308
BioMed research international 2018;2018:6254308
Overexpression of YOD1 Promotes the Migration of Human Oral Keratinocytes by Enhancing TGF-β3 Signaling.
Ju Q, Li MX, Chen G, Wang HX, Shi QM, Ge X, Ding Z, Wang Q, Xu LC
Biomedical and environmental sciences : BES 2018 Jul;31(7):499-506
Biomedical and environmental sciences : BES 2018 Jul;31(7):499-506
Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes.
Wang X, Dong C, Li N, Ma Q, Yun Z, Cai C, An M, Ma B
Molecular medicine reports 2018 Jan;17(1):1893-1900
Molecular medicine reports 2018 Jan;17(1):1893-1900
Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells.
Chuang TD, Khorram O
Reproductive sciences (Thousand Oaks, Calif.) 2017 Sep;24(9):1253-1263
Reproductive sciences (Thousand Oaks, Calif.) 2017 Sep;24(9):1253-1263
Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling.
Wang L, Hu L, Zhou X, Xiong Z, Zhang C, Shehada HMA, Hu B, Song J, Chen L
Scientific reports 2017 Oct 17;7(1):13321
Scientific reports 2017 Oct 17;7(1):13321
CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-β3 function.
Yoshioka Y, Ono M, Maeda A, Kilts TM, Hara ES, Khattab H, Ueda J, Aoyama E, Oohashi T, Takigawa M, Young MF, Kuboki T
Bone 2016 Feb;83:162-170
Bone 2016 Feb;83:162-170
Transforming growth factor beta 3 involved in the pathogenesis of synovial chondromatosis of temporomandibular joint.
Li Y, El Mozen LA, Cai H, Fang W, Meng Q, Li J, Deng M, Long X
Scientific reports 2015 Mar 6;5:8843
Scientific reports 2015 Mar 6;5:8843
SIX1 promotes tumor lymphangiogenesis by coordinating TGFβ signals that increase expression of VEGF-C.
Liu D, Li L, Zhang XX, Wan DY, Xi BX, Hu Z, Ding WC, Zhu D, Wang XL, Wang W, Feng ZH, Wang H, Ma D, Gao QL
Cancer research 2014 Oct 1;74(19):5597-607
Cancer research 2014 Oct 1;74(19):5597-607
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 18942-1-AP(TGFB3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The TGF-beta 3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TGF-beta 3. This antibody recognizes human,mouse,rat antigen. The TGF-beta 3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.