ABIN350259

antibody from antibodies-online

Targeting: CREM hCREM-2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350259

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350259, RRID:AB_10785306

Product name

anti-CAMP Responsive Element Modulator (CREM) (pSer271), (pSer274) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide to phospho S271 & S274 of human CREM (cAMP-responsive element modulator, Inducible cAMP early repressor, ICER) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse and dog.

Description

Whole serum

Reactivity

Human, Mouse, Rat

Host

Sheep

Epitope

pSer271,pSer274

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.

Nagamori I, Yomogida K, Adams PD, Sassone-Corsi P, Nojima H
The Journal of biological chemistry 2006 Jun 2;281(22):15073-81

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Differential regulation of cyclic adenosine 3',5'-monophosphate (cAMP) response element-binding protein and cAMP response element modulator messenger ribonucleic acid transcripts by follicle-stimulating hormone and androgen in the adult rat testis.

West AP, Sharpe RM, Saunders PT
Biology of reproduction 1994 Apr;50(4):869-81

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Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript.

Masquilier D, Foulkes NS, Mattei MG, Sassone-Corsi P
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993 Nov;4(11):931-7