Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 21049-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21049-1-AP, RRID:AB_10733759
- Product name
- FLT3 antibody
- Antibody type
- Polyclonal
- Description
- FLT3 antibody (Cat. #21049-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells.
Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.
An analysis of monocytes and dendritic cells differentiated from human peripheral blood monocyte-derived induced pluripotent stem cells.
The angiogenic factor Egfl7 alters thymogenesis by activating Flt3 signaling.
Qian F, Nettleford SK, Zhou J, Arner BE, Hall MA, Sharma A, Annageldiyev C, Rossi RM, Tukaramrao DB, Sarkar D, Hegde S, Gandhi UH, Finch ER, Goodfield L, Quickel MD, Claxton DF, Paulson RF, Prabhu KS
Cell reports 2023 Jul 25;42(7):112794
Cell reports 2023 Jul 25;42(7):112794
Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.
Kang JB, Chen L, Leng XJ, Wang JJ, Cheng Y, Wu SH, Ma YY, Yang LJ, Cao YH, Yang X, Tong ZJ, Wu JZ, Wang YB, Zhou H, Liu JC, Ding N, Dai WC, Yu YC, Xue X, Sun SL, Dai XB, Chang L, Wang XL, Li NG, Shi ZH
Bioorganic & medicinal chemistry 2022 Sep 15;70:116937
Bioorganic & medicinal chemistry 2022 Sep 15;70:116937
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
Jiang X, Zhang K, Gao C, Ma W, Liu M, Guo X, Bao G, Han B, Hu H, Zhao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22672
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22672
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.
Cao S, Ma L, Liu Y, Wei M, Yao Y, Li C, Wang R, Liu N, Dong Z, Li X, Li M, Wang X, Yang C, Yang G
Journal of medicinal chemistry 2021 Nov 25;64(22):16497-16511
Journal of medicinal chemistry 2021 Nov 25;64(22):16497-16511
An analysis of monocytes and dendritic cells differentiated from human peripheral blood monocyte-derived induced pluripotent stem cells.
Hiramatsu N, Yamamoto N, Isogai S, Onouchi T, Hirayama M, Maeda S, Ina T, Kondo M, Imaizumi K
Medical molecular morphology 2020 Jun;53(2):63-72
Medical molecular morphology 2020 Jun;53(2):63-72
The angiogenic factor Egfl7 alters thymogenesis by activating Flt3 signaling.
Salama Y, Hattori K, Heissig B
Biochemical and biophysical research communications 2017 Aug 19;490(2):209-216
Biochemical and biophysical research communications 2017 Aug 19;490(2):209-216
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FLT3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human FLT3. This antibody recognizes human,mouse,rat antigen. The FLT3 antibody has been validated for the following applications: ELISA, WB analysis.