PAB17006

antibody from Abnova Corporation

Targeting: FLT3 CD135, FLK2, STK1

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB17006

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB17006, RRID:AB_10629943

Product name

FLT3 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of FLT3.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53.

Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT
Blood 2007 Mar 15;109(6):2589-96

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Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2.

Heiss E, Masson K, Sundberg C, Pedersen M, Sun J, Bengtsson S, Rönnstrand L
Blood 2006 Sep 1;108(5):1542-50

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FLT3 tyrosine kinase as a target molecule for selective antileukemia therapy.

Naoe T, Kiyoe H, Yamamoto Y, Minami Y, Yamamoto K, Ueda R, Saito H
Cancer chemotherapy and pharmacology 2001 Aug;48 Suppl 1:S27-30

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FLT3 polyclonal antibody (Cat # PAB17006).

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)