Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 14616-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14616-1-AP, RRID:AB_2242343
- Product name
- ADCY6 antibody
- Antibody type
- Polyclonal
- Description
- ADCY6 antibody (Cat. #14616-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Forskolin is an effective therapeutic small molecule for the treatment of hypertrophic cardiomyopathy through ADCY6/cAMP/PKA pathway.
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Knockdown of GPSM1 Inhibits the Proliferation and Promotes the Apoptosis of B-Cell Acute Lymphoblastic Leukemia Cells by Suppressing the ADCY6-RAPGEF3-JNK Signaling Pathway.
Purβ promotes hepatic glucose production by increasing Adcy6 transcription.
Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G.
Wang W, Xue Y, Li D, Shao C, Wu K, Sun N, Chen Q
European journal of pharmacology 2024 Sep 5;978:176770
European journal of pharmacology 2024 Sep 5;978:176770
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Li X, Ding K, Li X, Yuan B, Wang Y, Yao Z, Wang S, Huang H, Xu B, Xie L, Deng T, Chen XW, Chen Z
Nature communications 2022 Aug 4;13(1):4549
Nature communications 2022 Aug 4;13(1):4549
Knockdown of GPSM1 Inhibits the Proliferation and Promotes the Apoptosis of B-Cell Acute Lymphoblastic Leukemia Cells by Suppressing the ADCY6-RAPGEF3-JNK Signaling Pathway.
Zhang Y, Zhou B, Sun J, He Q, Zhao Y
Pathology oncology research : POR 2021;27:643376
Pathology oncology research : POR 2021;27:643376
Purβ promotes hepatic glucose production by increasing Adcy6 transcription.
Jia L, Jiang Y, Li X, Chen Z
Molecular metabolism 2020 Jan;31:85-97
Molecular metabolism 2020 Jan;31:85-97
Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G.
Saito M, Cui L, Hirano M, Li G, Yanagisawa T, Sato T, Sukegawa J
Molecular pharmacology 2019 Oct;96(4):441-451
Molecular pharmacology 2019 Oct;96(4):441-451
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The ADCY6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ADCY6. This antibody recognizes human, mouse, rat antigen. The ADCY6 antibody has been validated for the following applications: ELISA, WB analysis.