GTX47798

antibody from GeneTex

Targeting: ADCY6 AC6

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

GTX47798

Provider

GeneTex

Proper citation

GeneTex Cat#GTX47798, RRID:AB_11177344

Product name

Adenylate cyclase 6 antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat

Host

Rabbit

References

Submitted references

Role of calcium in adult onset polycystic kidney disease.

Yanda MK, Liu Q, Cebotaru V, Guggino WB, Cebotaru L
Cellular signalling 2019 Jan;53:140-150

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A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector.

Yanda MK, Liu Q, Cebotaru L
The Journal of biological chemistry 2018 Jul 20;293(29):11513-11526

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Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca(2+) in knock-out mouse models of polycystic kidney disease.

Yanda MK, Liu Q, Cebotaru V, Guggino WB, Cebotaru L
The Journal of biological chemistry 2017 Oct 27;292(43):17897-17908

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An inhibitor of histone deacetylase 6 activity, ACY-1215, reduces cAMP and cyst growth in polycystic kidney disease.

Yanda MK, Liu Q, Cebotaru L
American journal of physiology. Renal physiology 2017 Oct 1;313(4):F997-F1004

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Western blot of Adenylate cyclase 6 using GTX47798 antibody 1:500 in diluObuffer. Apparent MW of PAC6 is 130kDa. The antibody also labels a light band of 65kDa, the identity of this band is not known.