BS1582

antibody from Bioworld Technology, Inc

Targeting: PRKD1 PKC-mu, PKCM, PKD, PRKCM

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS1582

Provider

Bioworld Technology, Inc

Proper citation

Bioworld Technology Cat#BS1582, RRID:AB_1663237

Product name

PKD1 (L905) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 881-924 of Human PKD1.

Description

Activation of PKC is one of the earliest events in a cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and muscle contraction. Protein kinase D (PKD), also called PKCÃ×, is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway. In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCÃ×. Phosphorylation at Ser916 correlates with PKD/PKCÃ× catalytic activity.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.