ABIN362138

antibody from antibodies-online

Targeting: MAP2K3 MAPKK3, MEK3, MKK3, PRKMK3

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362138

Provider

antibodies-online

Product name

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (pSer189) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer189 (V-D-S (p) -V-A) derived from Human MKK3. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Rat

Host

Rabbit

Epitope

pSer189

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence.

Wang W, Chen JX, Liao R, Deng Q, Zhou JJ, Huang S, Sun P
Molecular and cellular biology 2002 May;22(10):3389-403

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.

Raingeaud J, Whitmarsh AJ, Barrett T, Dérijard B, Davis RJ
Molecular and cellular biology 1996 Mar;16(3):1247-55