ABIN360822

antibody from antibodies-online

Targeting: DUSP1 CL100, HVH1, MKP-1, PTPN10

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN360822

Provider

antibodies-online

Product name

anti-Dual Specificity Phosphatase 1 (DUSP1) (N-Term) antibody

Antibody type

Polyclonal

Description

Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival.

Wu W, Pew T, Zou M, Pang D, Conzen SD
The Journal of biological chemistry 2005 Feb 11;280(6):4117-24

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Role of CL-100, a dual specificity phosphatase, in thrombin-induced endothelial cell activation.

Chandrasekharan UM, Yang L, Walters A, Howe P, DiCorleto PE
The Journal of biological chemistry 2004 Nov 5;279(45):46678-85

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Mitogen-activated protein kinase phosphatase-1 is overexpressed in non-small cell lung cancer and is an independent predictor of outcome in patients.

Vicent S, Garayoa M, López-Picazo JM, Lozano MD, Toledo G, Thunnissen FB, Manzano RG, Montuenga LM
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Jun 1;10(11):3639-49

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Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role.

Small GW, Shi YY, Edmund NA, Somasundaram S, Moore DT, Orlowski RZ
Molecular pharmacology 2004 Dec;66(6):1478-90

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Inhibition of MKP-1 expression potentiates JNK related apoptosis in renal cancer cells.

Mizuno R, Oya M, Shiomi T, Marumo K, Okada Y, Murai M
The Journal of urology 2004 Aug;172(2):723-7