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- References [15]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15882-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15882-1-AP, RRID:AB_2237574
- Product name
- PPP2R1A antibody
- Antibody type
- Polyclonal
- Description
- PPP2R1A antibody (Cat. #15882-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphoethanolamine cytidylyltransferase 2 exerts an anti-tumor role in clear cell renal cell carcinoma by modulating the hippo/YAP1 signaling pathway in a PPP2R1A-dependent manner.
Covalent targeting of PP2A scaffold subunit PPP2R1A by Pseudolarolide B enhances holoenzyme assembly to exert anti-inflammatory activity.
STK39 inhibits antiviral immune response by inhibiting DCAF1-mediated PP2A degradation.
DSS1 is required for proper Integrator-PP2A function.
IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth.
Silencing PPP2R1A inhibits the progression of gastric cancer cells.
PPP2R1A silencing suppresses LUAD progression by sensitizing cells to nelfinavir-induced apoptosis and pyroptosis.
Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter.
Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates.
Classical swine fever virus NS5A protein activates autophagy via the PP2A-DAPK3-Beclin 1 axis.
GPx1 promotes hypertrophic differentiation of chondrocytes through modulation of akt signaling in a non-monotonic manner.
TurboID Screening of the OmpP2 Protein Reveals Host Proteins Involved in Recognition and Phagocytosis of Glaesserella parasuis by iPAM Cells.
SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape.
BRG1 Activates PR65A Transcription to Regulate NO Bioavailability in Vascular Endothelial Cells.
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Nan N, Guo H, Huang Y, Chen J, Qiang X
Toxicology and applied pharmacology 2026 Jun;511:117786
Toxicology and applied pharmacology 2026 Jun;511:117786
Covalent targeting of PP2A scaffold subunit PPP2R1A by Pseudolarolide B enhances holoenzyme assembly to exert anti-inflammatory activity.
Li Y, Huang Y, Wang S, Xia H, Li J, Wu X, Lu Y, Ma B, Su G, Li Y
Bioorganic chemistry 2026 Jun 15;174:109684
Bioorganic chemistry 2026 Jun 15;174:109684
STK39 inhibits antiviral immune response by inhibiting DCAF1-mediated PP2A degradation.
Zhang C, Xu P, Wang Y, Chen X, Pan Y, Ma Z, Wang C, Xu H, Zhou G, Zhu F, Xia H
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1535-1551
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1535-1551
DSS1 is required for proper Integrator-PP2A function.
Xu C, Zhou QX, Zheng H, Song A, Zhao WY, Xu TT, Xiong Y, Zhang YJ, Huang Z, Xu Y, Cheng J, Chen FX
Nature communications 2025 Jul 5;16(1):6206
Nature communications 2025 Jul 5;16(1):6206
IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth.
Zhou B, Zhao Q, Hou G, He J, Sha N, Zheng K, Peng H, Wang W, Zhou Y, Chen T, Jiang Y
Cell reports 2025 Jan 28;44(1):115116
Cell reports 2025 Jan 28;44(1):115116
Silencing PPP2R1A inhibits the progression of gastric cancer cells.
Cheng G, Wusiman L, Song D, Zhang W
Journal of cancer research and clinical oncology 2025 Apr 18;151(4):142
Journal of cancer research and clinical oncology 2025 Apr 18;151(4):142
PPP2R1A silencing suppresses LUAD progression by sensitizing cells to nelfinavir-induced apoptosis and pyroptosis.
Liu Y, Ouyang L, Jiang S, Liang L, Chen Y, Mao C, Jiang Y, Cong L
Cancer cell international 2024 Apr 23;24(1):145
Cancer cell international 2024 Apr 23;24(1):145
Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter.
Zhang H, Han J, Zhang J, Miao J, Li F, Tang K, Zhou K, Duan B, Li W, Cheng J, Sun Y, Hou N, Huang C
Cell death discovery 2023 May 8;9(1):152
Cell death discovery 2023 May 8;9(1):152
Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates.
Fu Y, Jia X, Yuan J, Yang Y, Zhang T, Yu Q, Zhou J, Wang T
Developmental cell 2023 Mar 13;58(5):398-415.e7
Developmental cell 2023 Mar 13;58(5):398-415.e7
Classical swine fever virus NS5A protein activates autophagy via the PP2A-DAPK3-Beclin 1 axis.
Sun J, Yu H, Wang Y, Li L, Zhu J, Ma P, Feng Z, Tu C
Journal of virology 2023 Dec 21;97(12):e0098823
Journal of virology 2023 Dec 21;97(12):e0098823
GPx1 promotes hypertrophic differentiation of chondrocytes through modulation of akt signaling in a non-monotonic manner.
Mi S, Zhang J, Sun M, Huo X, Lv Y, Beier F, Lu S, Yan J
Experimental cell research 2023 Dec 15;433(2):113824
Experimental cell research 2023 Dec 15;433(2):113824
TurboID Screening of the OmpP2 Protein Reveals Host Proteins Involved in Recognition and Phagocytosis of Glaesserella parasuis by iPAM Cells.
Jiang C, Ma N, Cao H, Zeng W, Ren J, Hu Y, Zhou J, Zhang M, Li C, Lang Y, Li W, He Q
Microbiology spectrum 2022 Oct 26;10(5):e0230722
Microbiology spectrum 2022 Oct 26;10(5):e0230722
SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape.
Hu S, Peng L, Xu C, Wang Z, Song A, Chen FX
Molecular cell 2021 Nov 4;81(21):4425-4439.e6
Molecular cell 2021 Nov 4;81(21):4425-4439.e6
BRG1 Activates PR65A Transcription to Regulate NO Bioavailability in Vascular Endothelial Cells.
Chen B, Zhao Q, Xu T, Yu L, Zhuo L, Yang Y, Xu Y
Frontiers in cell and developmental biology 2020;8:774
Frontiers in cell and developmental biology 2020;8:774
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Zheng H, Qi Y, Hu S, Cao X, Xu C, Yin Z, Chen X, Li Y, Liu W, Li J, Wang J, Wei G, Liang K, Chen FX, Xu Y
Science (New York, N.Y.) 2020 Nov 27;370(6520)
Science (New York, N.Y.) 2020 Nov 27;370(6520)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15882-1-AP(PPP2R1A antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 15882-1-AP(PPP2R1A antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PPP2R1A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PPP2R1A. This antibody recognizes human,mouse,rat antigen. The PPP2R1A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
