CABT-B10507
antibody from Creative Diagnostics
Targeting: KCNQ1
JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1
Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations [0]
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- Product number
- CABT-B10507 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human KCNQ1 monoclonal antibody, clone T48B-20
- Antibody type
- Monoclonal
- Description
- This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- T48B-20
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
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