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- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13559-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13559-1-AP, RRID:AB_2227055
- Product name
- APC2 antibody
- Antibody type
- Polyclonal
- Description
- APC2 antibody (Cat. #13559-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Interactome mapping in human excitatory neurons reveals novel risk genes and pathways in Alzheimer's disease.
CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7-Positive Vesicle Fusion with Target Membranes.
Human papillomavirus16 E7 enhances cell stemness by regulating the APC2/SPIN4/β-catenin axis in cervical cancer.
UBE2C promotes pancreatic tumorigenesis by KRAS stabilization via APC/C(CDH1)-mediated WDR76 degradation.
CCDC68 Maintains Mitotic Checkpoint Activation by Promoting CDC20 Integration into the MCC.
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
CENP-F-dependent DRP1 function regulates APC/C activity during oocyte meiosis I.
APC2(CDH1) negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.
The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.
Wei X, Munechika K, Sun Y, Wan Y, Xia T, Hou Y, Song W, Yugandhar K, Wang Y, Lee SI, Sha Z, Zhou Y, Feng W, Zhu J, Tang Y, Luo W, Cheng F, Gan L, Yu H
bioRxiv : the preprint server for biology 2026 Mar 16;
bioRxiv : the preprint server for biology 2026 Mar 16;
CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7-Positive Vesicle Fusion with Target Membranes.
Tian Y, Li J, Kang J, Xu X, Wang B, Lou S, Li J, Yang Y, Zhang Y, Zheng Y, Weng J, Liang Y, Ma W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e04665
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e04665
Human papillomavirus16 E7 enhances cell stemness by regulating the APC2/SPIN4/β-catenin axis in cervical cancer.
Shen T, Ma Y, Wu T, Cao Z, Yi P, Huang X, Yang S
Oncogenesis 2026 Feb 24;15(1)
Oncogenesis 2026 Feb 24;15(1)
UBE2C promotes pancreatic tumorigenesis by KRAS stabilization via APC/C(CDH1)-mediated WDR76 degradation.
Wang L, Chen X, Qu R, Shao S, Gong L, Li T, Jiang S, Lu Y, Ma Y, Sun Y, Cui D, Xiong X, Zhao Y
Cancer letters 2025 Aug 30;633:218013
Cancer letters 2025 Aug 30;633:218013
CCDC68 Maintains Mitotic Checkpoint Activation by Promoting CDC20 Integration into the MCC.
Li Q, Chen Q, Zheng T, Wang F, Teng J, Zhou H, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2406009
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2406009
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
Hao Z, Yuan Q, Tang H, Lei C, Chen Y, Su H, Zhang C
The FEBS journal 2023 Aug;290(15):3858-3876
The FEBS journal 2023 Aug;290(15):3858-3876
CENP-F-dependent DRP1 function regulates APC/C activity during oocyte meiosis I.
Zhou CJ, Wang XY, Dong YH, Wang DH, Han Z, Zhang XJ, Sun QY, Carroll J, Liang CG
Nature communications 2022 Dec 13;13(1):7732
Nature communications 2022 Dec 13;13(1):7732
APC2(CDH1) negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.
Chen A, Bai L, Zhong K, Shu X, Wang A, Xiao Y, Zhang K, Shen C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12009-12023
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12009-12023
The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.
Ha K, Ma C, Lin H, Tang L, Lian Z, Zhao F, Li JM, Zhen B, Pei H, Han S, Malumbres M, Jin J, Chen H, Zhao Y, Zhu Q, Zhang P
Nature communications 2017 Jun 12;8:15751
Nature communications 2017 Jun 12;8:15751
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 13559-1-AP(ANAPC2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 13559-1-AP(ANAPC2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The APC2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human APC2. This antibody recognizes human,mouse,rat antigen. The APC2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
