TNNI2

gene product
AMCD2B, DA2B, FSSV
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
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403 antibodies from 30 providers.

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antibodies-online
132 antibodies
Biorbyt
14 antibodies
Acris Antibodies GmbH
8 antibodies
Novus Biologicals
27 antibodies
GeneTex
7 antibodies
OriGene
14 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
71 antibodies
Abnova Corporation
7 antibodies
NovoPro Bioscience Inc.
6 antibodies
Affinity Biosciences
1 antibody
Santa Cruz Biotechnology
1 antibody
Invitrogen Antibodies
6 antibodies
Proteintech Group
2 antibodies
Abgent
9 antibodies
St John's Laboratory
6 antibodies
Antibodies.com
2 antibodies
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
Creative Biolabs
23 antibodies
Creative Diagnostics
10 antibodies
Aviva Systems Biology
2 antibodies
United States Biological
32 antibodies
ProSci
5 antibodies
RayBiotech, Inc.
2 antibodies
Abbexa
1 antibody
Abbiotec
1 antibody
MyBioSource
5 antibodies
GenWay
2 antibodies
Sigma-Aldrich
2 antibodies