Antibody data

Product number
BS60979 - Provider product page
Provider
Bioworld Technology, Inc
Product name
INHA polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human INHA.
Description
Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same Ï« subunit, covalently linked to 1 of 2 distinct subunits, ÉÇ-Ï« or ÉÇ-ÉÇ. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor ÉÇ (TGFÉÇ) superfamily of growth and differentiation factors. TGFÉÇ proteins affect a range of tissues and systems beyond their role in reproduction. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, placenta and, most notably, anterior pituitary. Inhibin Ï«-subunit gene expression is down regulated in human prostate cancer, suggesting a tumor-suppressive role. The human Inhibin Ï« gene maps to chromosome 2q33-q36.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
INHA protein structure - BS60979 shown in red.