Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60979 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- INHA polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human INHA.
- Description
- Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same Ï« subunit, covalently linked to 1 of 2 distinct subunits, ÉÇ-Ï« or ÉÇ-ÉÇ. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor ÉÇ (TGFÉÇ) superfamily of growth and differentiation factors. TGFÉÇ proteins affect a range of tissues and systems beyond their role in reproduction. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, placenta and, most notably, anterior pituitary. Inhibin Ï«-subunit gene expression is down regulated in human prostate cancer, suggesting a tumor-suppressive role. The human Inhibin Ï« gene maps to chromosome 2q33-q36.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of INHA pAb at 1:500 dilutionLane1:sp2/0 whole cell lysateLane2:PC12 whole cell lysateLane3:H9C2 whole cell lysateLane4:A549 whole cell lysate