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antibody from antibodies-online
Targeting: MCM2
BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030
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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN152064 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Minichromosome Maintenance Complex Component 2 (MCM2) (pSer108) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pSer108
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression.
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
Replication initiation complex formation in the absence of nuclear function in Xenopus.
Plx1 is required for chromosomal DNA replication under stressful conditions.
The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases.
Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T
Cancer research 2011 Sep 1;71(17):5621-5
Cancer research 2011 Sep 1;71(17):5621-5
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang TH, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-Kaçmaz K
The Journal of biological chemistry 2010 May 28;285(22):16562-71
The Journal of biological chemistry 2010 May 28;285(22):16562-71
Replication initiation complex formation in the absence of nuclear function in Xenopus.
Krasinska L, Fisher D
Nucleic acids research 2009 Apr;37(7):2238-48
Nucleic acids research 2009 Apr;37(7):2238-48
Plx1 is required for chromosomal DNA replication under stressful conditions.
Trenz K, Errico A, Costanzo V
The EMBO journal 2008 Mar 19;27(6):876-85
The EMBO journal 2008 Mar 19;27(6):876-85
The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.
Liu E, Lee AY, Chiba T, Olson E, Sun P, Wu X
The Journal of cell biology 2007 Nov 19;179(4):643-57
The Journal of cell biology 2007 Nov 19;179(4):643-57
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases.
Cortez D, Glick G, Elledge SJ
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 6;101(27):10078-83
Proceedings of the National Academy of Sciences of the United States of America 2004 Jul 6;101(27):10078-83
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Supportive validation
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- IHC
Supportive validation
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