Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN1881543 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Makorin Ring Finger Protein 1 (MKRN1) (Center), (AA 184-213) antibody
- Antibody type
- Polyclonal
- Antigen
- This MKRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-213 amino acids from the Central region of human MKRN1.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center,AA 184-213
- Antibody clone number
- RB40959
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references MKRN1 induces degradation of West Nile virus capsid protein by functioning as an E3 ligase.
Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis.
The ancient source of a distinct gene family encoding proteins featuring RING and C(3)H zinc-finger motifs with abundant expression in developing brain and nervous system.
Ko A, Lee EW, Yeh JY, Yang MR, Oh W, Moon JS, Song J
Journal of virology 2010 Jan;84(1):426-36
Journal of virology 2010 Jan;84(1):426-36
Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis.
Lee EW, Lee MS, Camus S, Ghim J, Yang MR, Oh W, Ha NC, Lane DP, Song J
The EMBO journal 2009 Jul 22;28(14):2100-13
The EMBO journal 2009 Jul 22;28(14):2100-13
The ancient source of a distinct gene family encoding proteins featuring RING and C(3)H zinc-finger motifs with abundant expression in developing brain and nervous system.
Gray TA, Hernandez L, Carey AH, Schaldach MA, Smithwick MJ, Rus K, Marshall Graves JA, Stewart CL, Nicholls RD
Genomics 2000 May 15;66(1):76-86
Genomics 2000 May 15;66(1):76-86
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- MKRN1 Antibody (Center) (ABIN1881543) western blot analysis in A549 cell line lysates (35 μg/lane). This demonstrates the MKRN1 antibody detected the MKRN1 protein (arrow).