Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- NB600-713 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-713, RRID:AB_2123531
- Product name
- Mouse Monoclonal Amylin Antibody
- Antibody type
- Monoclonal
- Description
- Tissue culture supernatant. The is of high affinity, and stains islet amyloid peptide in intra-cellular insulin granules, intra-cellular amyloid and extra-cellular islet amyloid.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway.
Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition.
Amyloid oligomers in diabetic and nondiabetic human pancreas.
Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey.
Cloning and expression of human islet amyloid polypeptide in cultured cells.
Amylin deposition in the kidney of patients with diabetic nephropathy.
Gurlo T, Ryazantsev S, Huang CJ, Yeh MW, Reber HA, Hines OJ, O'Brien TD, Glabe CG, Butler PC
The American journal of pathology 2010 Feb;176(2):861-9
The American journal of pathology 2010 Feb;176(2):861-9
Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition.
Zhao H, Guan J, Lee HM, Sui Y, He L, Siu JJ, Tse PP, Tong PC, Lai FM, Chan JC
Pancreas 2010 Aug;39(6):843-6
Pancreas 2010 Aug;39(6):843-6
Amyloid oligomers in diabetic and nondiabetic human pancreas.
Zhao HL, Sui Y, Guan J, He L, Gu XM, Wong HK, Baum L, Lai FM, Tong PC, Chan JC
Translational research : the journal of laboratory and clinical medicine 2009 Jan;153(1):24-32
Translational research : the journal of laboratory and clinical medicine 2009 Jan;153(1):24-32
Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey.
Nakamura S, Okabayashi S, Ageyama N, Koie H, Sankai T, Ono F, Fujimoto K, Terao K
Veterinary pathology 2008 Jan;45(1):67-72
Veterinary pathology 2008 Jan;45(1):67-72
Cloning and expression of human islet amyloid polypeptide in cultured cells.
Bhattacharya S, Latha JN, Kumresan R, Singh S
Biochemical and biophysical research communications 2007 May 11;356(3):622-8
Biochemical and biophysical research communications 2007 May 11;356(3):622-8
Amylin deposition in the kidney of patients with diabetic nephropathy.
Gong W, Liu ZH, Zeng CH, Peng A, Chen HP, Zhou H, Li LS
Kidney international 2007 Jul;72(2):213-8
Kidney international 2007 Jul;72(2):213-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Amylin Antibody (R10/99) [NB600-713] - Human pancreas with Mouse anti Human Amylin Peptide, showing labeling of Islet of Langerhans.