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LearnABIN488153
antibody from antibodies-online
Targeting: CYP19A1
ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations [0]
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- Product number
- ABIN488153 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 376-390) antibody
- Antibody type
- Monoclonal
- Description
- Supernatant
- Reactivity
- Human, Mouse, Rat, Bovine, Porcine, Rabbit, Sheep, Simian
- Host
- Mouse
- Epitope
- AA 376-390
- Isotype
- IgG
- Antibody clone number
- H4
- Vial size
- 0.2 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism.
BRCA1/BARD1 complex interacts with steroidogenic factor 1--A potential mechanism for regulation of aromatase expression by BRCA1.
The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN.
Testosterone, not 5α-dihydrotestosterone, stimulates LRH-1 leading to FSH-independent expression of Cyp19 and P450scc in granulosa cells.
The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues.
Somatic sex identity is cell autonomous in the chicken.
Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells.
Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus.
Absence of aromatase protein and mRNA expression in endometriosis.
Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells.
Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway.
A Role of CREB in BRCA1 Constitutive Promoter Activity and Aromatase Basal Expression.
Ubiquitination and proteasome-mediated degradation of BRCA1 and BARD1 during steroidogenesis in human ovarian granulosa cells.
Detection of aromatase and estrogen receptors (ERalpha, ERbeta1, ERbeta2) in human Leydig cell tumor.
Development and validation of a new monoclonal antibody to mammalian aromatase.
Schicht M, Ernst J, Nielitz A, Fester L, Tsokos M, Guddat SS, Bräuer L, Bechmann J, Delank KS, Wohlrab D, Paulsen F, Claassen H
Arthritis research & therapy 2014 Apr 11;16(2):R93
Arthritis research & therapy 2014 Apr 11;16(2):R93
BRCA1/BARD1 complex interacts with steroidogenic factor 1--A potential mechanism for regulation of aromatase expression by BRCA1.
Lu Y, Kang T, Hu Y
The Journal of steroid biochemistry and molecular biology 2011 Jan;123(1-2):71-8
The Journal of steroid biochemistry and molecular biology 2011 Jan;123(1-2):71-8
The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN.
Horling K, Santos AN, Fischer B
Molecular human reproduction 2011 Feb;17(2):104-14
Molecular human reproduction 2011 Feb;17(2):104-14
Testosterone, not 5α-dihydrotestosterone, stimulates LRH-1 leading to FSH-independent expression of Cyp19 and P450scc in granulosa cells.
Wu YG, Bennett J, Talla D, Stocco C
Molecular endocrinology (Baltimore, Md.) 2011 Apr;25(4):656-68
Molecular endocrinology (Baltimore, Md.) 2011 Apr;25(4):656-68
The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues.
Jeong JH, Jung YK, Kim HJ, Jin JS, Kim HN, Kang SM, Kim SY, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Kato S, Choi JY
Molecular and cellular biology 2010 May;30(10):2365-75
Molecular and cellular biology 2010 May;30(10):2365-75
Somatic sex identity is cell autonomous in the chicken.
Zhao D, McBride D, Nandi S, McQueen HA, McGrew MJ, Hocking PM, Lewis PD, Sang HM, Clinton M
Nature 2010 Mar 11;464(7286):237-242
Nature 2010 Mar 11;464(7286):237-242
Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells.
Catalano S, Malivindi R, Giordano C, Gu G, Panza S, Bonofiglio D, Lanzino M, Sisci D, Panno ML, Andò S
The Journal of biological chemistry 2010 Feb 19;285(8):5581-93
The Journal of biological chemistry 2010 Feb 19;285(8):5581-93
Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus.
Bender RA, Zhou L, Wilkars W, Fester L, Lanowski JS, Paysen D, König A, Rune GM
Cerebral cortex (New York, N.Y. : 1991) 2010 Dec;20(12):2985-95
Cerebral cortex (New York, N.Y. : 1991) 2010 Dec;20(12):2985-95
Absence of aromatase protein and mRNA expression in endometriosis.
Colette S, Lousse JC, Defrère S, Curaba M, Heilier JF, Van Langendonckt A, Mestdagt M, Foidart JM, Loumaye E, Donnez J
Human reproduction (Oxford, England) 2009 Sep;24(9):2133-41
Human reproduction (Oxford, England) 2009 Sep;24(9):2133-41
Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells.
Sirianni R, Chimento A, De Luca A, Zolea F, Carpino A, Rago V, Maggiolini M, Andò S, Pezzi V
The Journal of biological chemistry 2009 Oct 16;284(42):28905-16
The Journal of biological chemistry 2009 Oct 16;284(42):28905-16
Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway.
Barone I, Cui Y, Herynk MH, Corona-Rodriguez A, Giordano C, Selever J, Beyer A, Andò S, Fuqua SA
Cancer research 2009 Jun 1;69(11):4724-32
Cancer research 2009 Jun 1;69(11):4724-32
A Role of CREB in BRCA1 Constitutive Promoter Activity and Aromatase Basal Expression.
Ghosh S, Lu Y, Hu Y
International journal of biomedical science : IJBS 2008 Dec 15;4(4):260-265
International journal of biomedical science : IJBS 2008 Dec 15;4(4):260-265
Ubiquitination and proteasome-mediated degradation of BRCA1 and BARD1 during steroidogenesis in human ovarian granulosa cells.
Lu Y, Amleh A, Sun J, Jin X, McCullough SD, Baer R, Ren D, Li R, Hu Y
Molecular endocrinology (Baltimore, Md.) 2007 Mar;21(3):651-63
Molecular endocrinology (Baltimore, Md.) 2007 Mar;21(3):651-63
Detection of aromatase and estrogen receptors (ERalpha, ERbeta1, ERbeta2) in human Leydig cell tumor.
Carpino A, Rago V, Pezzi V, Carani C, Andò S
European journal of endocrinology 2007 Aug;157(2):239-44
European journal of endocrinology 2007 Aug;157(2):239-44
Development and validation of a new monoclonal antibody to mammalian aromatase.
Turner KJ, Macpherson S, Millar MR, McNeilly AS, Williams K, Cranfield M, Groome NP, Sharpe RM, Fraser HM, Saunders PT
The Journal of endocrinology 2002 Jan;172(1):21-30
The Journal of endocrinology 2002 Jan;172(1):21-30
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