GTX14052

antibody from GeneTex

Targeting: TGFB1 CED, DPD1, TGFB, TGFbeta

Blocking/Neutralizing (Data presented on provider website)

Antibody Data

Product number

GTX14052

Provider

GeneTex

Product name

TGF beta antibody [1D11.16.8]

Antibody type

Monoclonal

Reactivity

Human, Mouse

Host

Mouse

References

Submitted references

HDAC inhibitors promote intestinal epithelial regeneration via autocrine TGFβ1 signalling in inflammation.

Friedrich M, Gerbeth L, Gerling M, Rosenthal R, Steiger K, Weidinger C, Keye J, Wu H, Schmidt F, Weichert W, Siegmund B, Glauben R
Mucosal immunology 2019 May;12(3):656-667

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Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology.

Okrah K, Tarighat S, Liu B, Koeppen H, Wagle MC, Cheng G, Sun C, Dey A, Chang MT, Sumiyoshi T, Mounir Z, Cummings C, Hampton G, Amler L, Fridlyand J, Hegde PS, Turley SJ, Lackner MR, Huang SM
NPJ precision oncology 2018;2:25

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CXCL6-EGFR-induced Kupffer cells secrete TGF-β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C-MYC/EZH2 pathway in liver fibrosis.

Cai X, Li Z, Zhang Q, Qu Y, Xu M, Wan X, Lu L
Journal of cellular and molecular medicine 2018 Oct;22(10):5050-5061

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Intestinal barrier regulates immune responses in the liver via IL-10-producing macrophages.

Taniki N, Nakamoto N, Chu PS, Mikami Y, Amiya T, Teratani T, Suzuki T, Tsukimi T, Fukuda S, Yamaguchi A, Shiba S, Miyake R, Katayama T, Ebinuma H, Kanai T
JCI insight 2018 Jun 21;3(12)