Explore
Validate
Learn
Western blot
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AB-101-NA - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-TGF-beta 1/1.2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Chinese hamster ovary cell line CHO-derived recombinant human TGF‑β1 (R&D Systems, Catalog # 240-B), Ala279-Ser390
- Description
- Ion exchange-purified from egg yolks
- Host
- Chicken/Avian
- Antigen sequence
P01137- Isotype
- IgY
- Vial size
- 1 mg
Submitted references Cancer-associated fibroblasts regulate keratinocyte cell-cell adhesion via TGF-β-dependent pathways in genotype-specific oral cancer.
Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2.
Isoform specificity of commercially-available anti-TGF-beta antibodies.
Isoform specificity of commercially-available anti-TGF-beta antibodies.
Cirillo N, Hassona Y, Celentano A, Lim KP, Manchella S, Parkinson EK, Prime SS
Carcinogenesis 2017 Jan;38(1):76-85
Carcinogenesis 2017 Jan;38(1):76-85
Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2.
van den Berk LC, Jansen BJ, Snowden S, Siebers-Vermeulen KG, Gilissen C, Kögler G, Figdor CG, Wheelock CE, Torensma R
Stem cells and development 2014 Jul 15;23(14):1582-93
Stem cells and development 2014 Jul 15;23(14):1582-93
Isoform specificity of commercially-available anti-TGF-beta antibodies.
Mozes MM, Hodics T, Kopp JB
Journal of immunological methods 1999 May 27;225(1-2):87-93
Journal of immunological methods 1999 May 27;225(1-2):87-93
Isoform specificity of commercially-available anti-TGF-beta antibodies.
Mozes MM, Hodics T, Kopp JB
Journal of immunological methods 1999 May 27;225(1-2):87-93
Journal of immunological methods 1999 May 27;225(1-2):87-93
No comments: Submit comment
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- TGF-beta 1 Inhibition of IL-4-dependent Cell Proliferation and Neutralization by TGF-beta 1/1.2 Antibody. Recombinant Human TGF-beta 1 (Catalog # 240-B) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Recombinant Human TGF-beta 1 (0.25 ng/mL) is neutralized (green line) by increasing concentrations of Chicken Anti-TGF-beta 1/1.2 Polyclonal Antibody (Catalog # AB-101-NA). The ND50 is typically 0.2-0.6 µg/mL.
