66590-1-Ig

antibody from Proteintech Group

Targeting: FOS AP-1, c-fos

Provider product page for 66590-1-Ig

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [71]
Comments [0]
Validations [0]

Submit

Product number: 66590-1-Ig - Provider product page
Provider: Proteintech Group
Product name: c-FOS antibody
Antibody type: Monoclonal
Description: KD/KO validated c-FOS antibody (Cat. #66590-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, rat, mouse and has been validated for the following applications: IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1G2C5
Vial size: 20ul, 150ul

FOS protein structure - 66590-1-Ig shown in red.

Submitted references D-alanine suppressed osteoclastogenesis derived from bone marrow macrophages and downregulated ERK/p38 signalling pathways.

Chang X, Deng J, Zhou F, Geng Z, Li X, Wang S
Archives of oral biology 2024 May;161:105912

Chalençon L, Midroit M, Athanassi A, Thevenet M, Breton M, Forest J, Richard M, Didier A, Mandairon N
Neurobiology of aging 2024 May;137:8-18

Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway.

Li Y, Lai J, Ran M, Yi T, Zhou L, Luo J, Liu X, Tang X, Huang M, Xie X, Li H, Yang Y, Zou W, Wu J
European journal of pharmacology 2024 May 15;971:176548

Gastrodin alleviates NTG-induced migraine-like pain via inhibiting succinate/HIF-1α/TRPM2 signaling pathway in trigeminal ganglion.

Ma C, Zhu C, Zhang Y, Yu M, Song Y, Chong Y, Yang Y, Zhu C, Jiang Y, Wang C, Cheng S, Jia K, Yu G, Li J, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155266

Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis.

Zhao Y, Ning J, Teng H, Deng Y, Sheldon M, Shi L, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L
Nature communications 2024 Mar 16;15(1):2384

Hydrogen sulfide mitigates memory impairments via the restoration of glutamatergic neurons in a mouse model of hemorrhage shock and resuscitation.

Song RX, Zhou TT, Jia SY, Li WG, Wang J, Li BD, Shan YD, Zhang LM, Li XM
Experimental neurology 2024 Jun;376:114758

Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.

Jin H, Liu C, Liu X, Wang H, Zhang Y, Liu Y, Li J, Yu Z, Liu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270

Wu DZ, Zhu GZ, Zhao K, Gao JW, Cai GX, Li HZ, Huang YS, Tu C, Zhuang JS, Huang ZW, Zhong ZM
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10

A new experimental rat model of nocebo-related nausea involving double mechanisms of observational learning and conditioning.

Zhang Y, Huang W, Shan Z, Zhou Y, Qiu T, Hu L, Yang L, Wang Y, Xiao Z
CNS neuroscience & therapeutics 2024 Feb;30(2):e14389

DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD.

Zhan Y, Huang Q, Deng Z, Chen S, Yang R, Zhang J, Zhang Y, Peng M, Wu J, Gu Y, Zeng Z, Xie J
Journal of advanced research 2024 Feb 10;

Long-term olfactory enrichment promotes non-olfactory cognition, noradrenergic plasticity and remodeling of brain functional connectivity in older mice.

Terrier C, Greco-Vuilloud J, Cavelius M, Thevenet M, Mandairon N, Didier A, Richard M
Neurobiology of aging 2024 Apr;136:133-156

Cerebral venous congestion alters CNS homeostatic plasticity, evoking tinnitus-like behavior.

Wei H, Jiang H, Zhou Y, Liu L, Ma W, Ni S, Zhou C, Ji X
Cell & bioscience 2024 Apr 9;14(1):47

Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia.

Zhou L, Ni C, Liao R, Tang X, Yi T, Ran M, Huang M, Liao R, Zhou X, Qin D, Wang L, Huang F, Xie X, Wan Y, Luo J, Wang Y, Wu J
eLife 2024 Apr 4;13

Integrating spatial transcriptomics and single-cell RNA-sequencing reveals the alterations in epithelial cells during nodular formation in benign prostatic hyperplasia.

Fei X, Liu J, Xu J, Jing H, Cai Z, Yan J, Wu Z, Li H, Wang Z, Shen Y
Journal of translational medicine 2024 Apr 23;22(1):380

5-HT3a receptor contributes to neuropathic pain by regulating central sensitization in a rat with brachial plexus avulsion.

Liao C, Guo J, Rui J, Gao K, Lao J, Zhou Y
Physiology & behavior 2024 Apr 1;277:114503

Inflammatory Genes Associated with Pristine Multi-Walled Carbon Nanotubes-Induced Toxicity in Ocular Cells.

Luo X, Xie D, Su J, Hu J
International journal of nanomedicine 2023;18:2465-2484

Determining the mechanism of pulsatilla decoction for treating gastric cancer: a network pharmacology-based study.

Huang S, Qu M, Chen X, Yu S, Kong F
Frontiers in oncology 2023;13:1174848

Aryl hydrocarbon receptors improve migraine-like pain behaviors in rats through the regulation of regulatory T cell/T-helper 17 cell-related homeostasis.

Yang L, Zhou Y, Zhang L, Wang Y, Zhang Y, Xiao Z
Headache 2023 Sep;63(8):1045-1060

KDM2B regulates inflammation and oxidative stress of sepsis via targeting NF-κB and AP-1 pathways.

Li X, Tian X, Zhang D
Immunity, inflammation and disease 2023 Sep;11(9):e985

Glymphatic Dysfunction in Migraine Mice Model.

Huang W, Zhang Y, Zhou Y, Zong J, Qiu T, Hu L, Pan S, Xiao Z
Neuroscience 2023 Sep 15;528:64-74

Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ.

Yao Z, Xu N, Shang G, Wang H, Tao H, Wang Y, Qin Z, Tan S, Feng J, Zhu J, Ma F, Tian S, Zhang Q, Qu Y, Hou J, Guo J, Zhao J, Hou Y, Ding C
Nature communications 2023 Sep 13;14(1):5670

Electroacupuncture inhibits hippocampal neuronal apoptosis and improves cognitive dysfunction in mice with vascular dementia via the JNK signaling pathway.

Liu Y, Yan Z, Ren Y, Wang W, Ke Y, Wang Y, Qi R
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2023 Oct;41(5):284-296

Mechanism underlying the effect of Pulsatilla decoction in hepatocellular carcinoma treatment: a network pharmacology and in vitro analysis.

Liu K, Cao Z, Huang S, Kong F
BMC complementary medicine and therapies 2023 Nov 10;23(1):405

Oral squamous cell carcinoma-derived EVs promote tumor progression by regulating inflammatory cytokines and the IL-17A-induced signaling pathway.

Li R, Zhou Y, Zhang M, Xie R, Duan N, Liu H, Qin Y, Ma J, Li Z, Ye P, Wang W, Wang X
International immunopharmacology 2023 May;118:110094

Long noncoding RNA Malat1 inhibits Tead3-Nfatc1-mediated osteoclastogenesis to suppress osteoporosis and bone metastasis.

Zhao Y, Teng H, Deng Y, Sheldon M, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L
Research square 2023 Mar 20;

PACAP6-38 improves nitroglycerin-induced central sensitization by modulating synaptic plasticity at the trigeminal nucleus caudalis in a male rat model of chronic migraine.

Zhang L, Zhou Y, Yang L, Wang Y, Xiao Z
The journal of headache and pain 2023 Jun 5;24(1):66

SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.

Shan Z, Wang Y, Qiu T, Zhou Y, Zhang Y, Hu L, Zhang L, Liang J, Ding M, Fan S, Xiao Z
The journal of headache and pain 2023 Jun 5;24(1):65

RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.

Han H, Lin T, Wang Z, Song J, Fang Z, Zhang J, You X, Du Y, Ye J, Zhou G
Pharmacological research 2023 Jan;187:106593

Mechanism of action of Daqinjiao decoction in treating cerebral small vessel disease explored using network pharmacology and molecular docking technology.

Wang ZY, Li MZ, Li WJ, Ouyang JF, Gou XJ, Huang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154538

Identification and Validation of Hub Genes in the Stenosis of Arteriovenous Fistula.

Li Y, Chen Y, Cui W, Wang J, Chen X, Zhang C, Zhu L, Bian C, Luo T
Journal of personalized medicine 2023 Jan 25;13(2)

Identification of genomic binding sites and direct target genes for the transcription factor DDIT3/CHOP.

Osman A, Lindén M, Österlund T, Vannas C, Andersson L, Escobar M, Ståhlberg A, Åman P
Experimental cell research 2023 Jan 1;422(1):113418

A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation.

Chen C, Wu M, Lei H, Cao Z, Wu F, Song Y, Zhang C, Qin M, Zhang C, Du R, Zhou J, Lu Y, Xie D, Zhang L
ACS pharmacology & translational science 2023 Feb 10;6(2):270-280

Antidepressant duloxetine hydrochloride protects against ovariectomy-induced bone loss in mice by inhibiting osteoclast differentiation.

Zhou W, Zhou W, Bi Y, Zhou Z, Zhou Z, Chen S, Xie G, Lian Z, Yuan G, Yao G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115810

Inhibiting PAC1 receptor internalization and endosomal ERK pathway activation may ameliorate hyperalgesia in a chronic migraine rat model.

Zhang L, Zhou Y, Wang Y, Yang L, Wang Y, Shan Z, Liang J, Xiao Z
Cephalalgia : an international journal of headache 2023 Apr;43(4):3331024231163131

Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.

Chen T, Zhang X, Ding X, Feng J, Zhang X, Xie D, Wang X
Molecular oncology 2023 Apr;17(4):695-709

Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.

Li D, Zhao Q, Xie L, Wang C, Tian Z, Tang H, Xia T, Wang A
The Science of the total environment 2023 Apr 15;869:161738

Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer.

Xu D, Tang WJ, Zhu YZ, Liu Z, Yang K, Liang MX, Chen X, Wu Y, Tang JH, Zhang W
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):246-257

Low-Intensity Focused Ultrasound Alleviates Chronic Neuropathic Pain-Induced Allodynia by Inhibiting Neuroplasticity in the Anterior Cingulate Cortex.

Wang B, Chen MX, Chen SC, Feng XJ, Liao YH, Zhao YX, Tie JS, Liu Y, Ao LJ
Neural plasticity 2022;2022:6472475

Identification of a biomarker and immune infiltration in perivascular adipose tissue of abdominal aortic aneurysm.

Wang X, He B, Deng Y, Liu J, Zhang Z, Sun W, Gao Y, Liu X, Zhen Y, Ye Z, Liu P, Wen J
Frontiers in physiology 2022;13:977910

Monascin abrogates RANKL-mediated osteoclastogenesis in RAW264.7 cells via regulating MAPKs signaling pathways.

Cheng Y, Liu H, Li J, Ma Y, Song C, Wang Y, Li P, Chen Y, Zhang Z
Frontiers in pharmacology 2022;13:950122

Trimethylamine-N-Oxide Promotes Osteoclast Differentiation and Bone Loss via Activating ROS-Dependent NF-κB Signaling Pathway.

Wang N, Hao Y, Fu L
Nutrients 2022 Sep 23;14(19)

CX-5461 is a potent immunosuppressant which inhibits T cell-mediated alloimmunity via p53-DUSP5.

Pan G, Zhang J, Han Y, Chen Y, Guo X, Cui X, Cheng M, Gao H, Wang J, Jiang F
Pharmacological research 2022 Mar;177:106120

The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation.

Wu Y, Teng Y, Zhang C, Pan Y, Zhang Q, Zhu X, Liu N, Su X, Lin J
Journal of nanobiotechnology 2022 Mar 9;20(1):120

Comprehensive analysis of circRNA-miRNA-mRNA in oral squamous cell carcinoma.

Cheng Y, Shi L, Yu Y
Archives of oral biology 2022 Jun;138:105346

Integrative epigenomic profiling reveal AP-1 is a key regulator in intrahepatich cholangiocarcinoma.

He K, Feng Y, An S, Liu F, Xiang G
Genomics 2022 Jan;114(1):241-252

Deer Antler Reserve Mesenchyme Cell-Conditioned Medium Reduces the Destruction of Periodontitis in Mice.

Lin H, Chen Z, Guo Q, Zhang P, Tian Y, Chen H, Zhao H, Shen Y
Stem cells and development 2022 Dec;31(23-24):766-776

Targeting TLR2/Rac1/cdc42/JNK Pathway to Reveal That Ruxolitinib Promotes Thrombocytopoiesis.

Yang S, Tang X, Wang L, Ni C, Wu Y, Zhou L, Zeng Y, Zhao C, Wu A, Wang Q, Xu X, Wang Y, Chen R, Zhang X, Zou L, Huang X, Wu J
International journal of molecular sciences 2022 Dec 17;23(24)

Gold Nanostrip Array-Mediated Wireless Electrical Stimulation for Accelerating Functional Neuronal Differentiation.

Yang H, Su Y, Sun Z, Ma B, Liu F, Kong Y, Sun C, Li B, Sang Y, Wang S, Li G, Qiu J, Liu C, Geng Z, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(22):e2202376

Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles.

Wu YL, Zhang CH, Teng Y, Pan Y, Liu NC, Liu PX, Zhu X, Su XL, Lin J
Military Medical Research 2022 Aug 23;9(1):46

CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway.

Zhang X, Guo Y, Xiao T, Li J, Guo A, Lei L, Jin C, Long Q, Su J, Yin M, Liu H, Chen C, Zhou Z, Zhu S, Tao J, Hu S, Chen X, Peng C
Journal of experimental & clinical cancer research : CR 2022 Aug 13;41(1):246

Dual Regulation of Tank Binding Kinase 1 by BRG1 in Hepatocytes Contributes to Reactive Oxygen Species Production.

Lv F, Shao T, Xue Y, Miao X, Guo Y, Wang Y, Xu Y
Frontiers in cell and developmental biology 2021;9:745985

Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction.

Tan J, Dai A, Pan L, Zhang L, Wang Z, Ke T, Sun W, Wu Y, Ding PH, Chen L
Journal of immunology research 2021;2021:9919024

Effects of Noninvasive Low-Intensity Focus Ultrasound Neuromodulation on Spinal Cord Neurocircuits In Vivo.

Liao YH, Chen MX, Chen SC, Luo KX, Wang B, Liu Y, Ao LJ
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8534466

RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway.

Han H, Lin T, Fang Z, Zhou G
BioMed research international 2021;2021:6697476

BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.

Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540

Single-Cell Transcriptome Analysis of Chronic Antibody-Mediated Rejection After Renal Transplantation.

Kong F, Ye S, Zhong Z, Zhou X, Zhou W, Liu Z, Lan J, Xiong Y, Ye Q
Frontiers in immunology 2021;12:767618

Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.

Wang F, Sun C, Lv X, Sun M, Si C, Zhen Y, Guo J, Sun W, Ye Z, Wen J, Liu P
Frontiers in physiology 2021;12:744219

KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia.

Zhang C, Shen L, Zhu Y, Xu R, Deng Z, Liu X, Ding Y, Wang C, Shi Y, Bei L, Wei D, Thorne RF, Zhang XD, Yu L, Chen S
Theranostics 2021;11(6):2691-2705

High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.

Si J, Tang X, Xu L, Fu H, Li H, He Y, Bao J, Tang J, Li A, Lu N, Yang C
Virology journal 2021 Nov 7;18(1):216

Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.

Jia X, Zhu H, Li G, Lan M, Li X, Huang M, Xu W, Wu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321

Neural processing of the reward value of pleasant odorants.

Midroit M, Chalençon L, Renier N, Milton A, Thevenet M, Sacquet J, Breton M, Forest J, Noury N, Richard M, Raineteau O, Ferdenzi C, Fournel A, Wesson DW, Bensafi M, Didier A, Mandairon N
Current biology : CB 2021 Apr 26;31(8):1592-1605.e9

LEF1/Id3/HRAS axis promotes the tumorigenesis and progression of esophageal squamous cell carcinoma.

Wang X, Zhao Y, Fei X, Lu Q, Li Y, Yuan Y, Lu C, Li C, Chen H
International journal of biological sciences 2020;16(13):2392-2404

Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.

Qi D, Liu H, Sun X, Luo D, Zhu M, Tao T, Gao C, Zhou C, Zhou W, Xiao J
Frontiers in pharmacology 2020;11:621110

Construction of a Mex3c Gene-Deficient Mouse Model to Study C-FOS Expression in Hypothalamic Nuclei and Observe Morphological Differences in Embryonic Neural Tube Development.

Du Y, Huo Q, Li T, Sun D, Sun T, Lu Z
Medical science monitor : international medical journal of experimental and clinical research 2020 Nov 16;26:e927334

Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice.

Kukharsky MS, Ninkina NN, An H, Telezhkin V, Wei W, Meritens CR, Cooper-Knock J, Nakagawa S, Hirose T, Buchman VL, Shelkovnikova TA
Translational psychiatry 2020 May 28;10(1):171

LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.

Li Q, Wang T, Huang S, Zuo Q, Jiang Z, Yang N, Sun L
Pregnancy hypertension 2020 Jul;21:50-57

LncRNA-SNHG15 enhances cell proliferation in colorectal cancer by inhibiting miR-338-3p.

Li M, Bian Z, Jin G, Zhang J, Yao S, Feng Y, Wang X, Yin Y, Fei B, You Q, Huang Z
Cancer medicine 2019 May;8(5):2404-2413

H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.

Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, Wei C, Xu C, Li H
Aging 2019 Mar 26;11(6):1745-1758

The preemptive analgesia of pre-electroacupuncture in rats with formalin-induced acute inflammatory pain.

Liu Q, Liu Y, Bian J, Li Q, Zhang Y
Molecular pain 2019 Jan-Dec;15:1744806919866529

Elevated expression of miR-146a correlates with high levels of immune cell exhaustion markers and suppresses cellular immune function in chronic HIV-1-infected patients.

Yu T, Ju Z, Luo M, Hu R, Teng Y, Xie L, Zhong C, Chen L, Hou W, Xiong Y, Feng Y
Scientific reports 2019 Dec 11;9(1):18829

MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression.

Chen S, Chen X, Xiu YL, Sun KX, Zhao Y
Cancer letters 2015 Jun 28;362(1):122-30

No comments: Submit comment

No validations: Submit validation data