Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Chromatin Immunoprecipitation [1]
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Validation data
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- Product number
- HPA018531 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA018531, RRID:AB_1846576
- Product name
- Anti-FOS
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FOS, Gene description: FBJ murine osteosarcoma viral oncogene homolog, Alternative Gene Names: AP-1, c-fos, Validated applications: ChIP, ICC, IHC, Uniprot ID: P01100, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
FOXA 2 controls the cis ‐regulatory networks of pancreatic cancer cells in a differentiation grade‐specific manner
Dissection of transcriptional and cis ‐regulatory control of differentiation in human pancreatic cancer
Early Growth Response 3 (Egr3) Is Highly Over-Expressed in Non-Relapsing Prostate Cancer but Not in Relapsing Prostate Cancer
Guo H, Golczer G, Wittner B, Langenbucher A, Zachariah M, Dubash T, Hong X, Comaills V, Burr R, Ebright R, Horwitz E, Vuille J, Hajizadeh S, Wiley D, Reeves B, Zhang J, Niederhoffer K, Lu C, Wesley B, Ho U, Nieman L, Toner M, Vasudevan S, Zou L, Mostoslavsky R, Maheswaran S, Lawrence M, Haber D
Molecular Cell 2021;81(19):4041-4058.e15
Molecular Cell 2021;81(19):4041-4058.e15
FOXA 2 controls the cis ‐regulatory networks of pancreatic cancer cells in a differentiation grade‐specific manner
Milan M, Balestrieri C, Alfarano G, Polletti S, Prosperini E, Spaggiari P, Zerbi A, Diaferia G, Natoli G
The EMBO Journal 2019;38(20)
The EMBO Journal 2019;38(20)
Dissection of transcriptional and cis ‐regulatory control of differentiation in human pancreatic cancer
Diaferia G, Balestrieri C, Prosperini E, Nicoli P, Spaggiari P, Zerbi A, Natoli G
The EMBO Journal 2016;35(6):595-617
The EMBO Journal 2016;35(6):595-617
Early Growth Response 3 (Egr3) Is Highly Over-Expressed in Non-Relapsing Prostate Cancer but Not in Relapsing Prostate Cancer
Agoulnik I, Pio R, Jia Z, Baron V, Mercola D
PLoS ONE 2013;8(1):e54096
PLoS ONE 2013;8(1):e54096
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-FOS (HPA018531, Lot 000015845) tested in MCF7 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.