PABW-172

antibody from Creative Biolabs

Targeting: TSHR LGR3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

PABW-172

Provider

Creative Biolabs

Product name

Recombinant Human Anti-TSHR Antibody (M22)

Antibody type

Monoclonal

Description

Recombinant Human Antibody (M22) is capable of binding to TSHR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TSHR mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti- TSHR proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. A human monoclonal autoantibody to the TSHR (M22), which is a powerful thyroid stimulator with high affinity for the receptor, and determined its crystal structure at 1.65A¡ã resolution.

Reactivity

Human

Host

Human

Isotype

IgG

Antibody clone number

M22

Storage

Store the antibody (in aliquots) at -20¡ãC. Avoid repeated freezing and thawing of samples.