ABIN2476797

antibody from antibodies-online

Targeting: TSHR LGR3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN2476797

Provider

antibodies-online

Product name

anti-Thyroid Stimulating Hormone Receptor (TSHR) antibody

Antibody type

Monoclonal

Description

Purified

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2C11

Vial size

0.2 mg

References

Submitted references

Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor.

Neumann S, Krause G, Claus M, Paschke R
Endocrinology 2005 Jan;146(1):477-85

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Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor.

Chazenbalk GD, Pichurin P, Chen CR, Latrofa F, Johnstone AP, McLachlan SM, Rapoport B
The Journal of clinical investigation 2002 Jul;110(2):209-17

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Identification of an important thyrotrophin binding site on the human thyrotrophin receptor using monoclonal antibodies.

Shepherd PS, Da Costa CR, Cridland JC, Gilmore KS, Johnstone AP
Molecular and cellular endocrinology 1999 Mar 25;149(1-2):197-206

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Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor.

Costagliola S, Rodien P, Many MC, Ludgate M, Vassart G
Journal of immunology (Baltimore, Md. : 1950) 1998 Feb 1;160(3):1458-65