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- References [7]
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- Product number
- 55053-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55053-1-AP, RRID:AB_10804173
- Product name
- UNC13A/Munc13-1 antibody
- Antibody type
- Polyclonal
- Description
- UNC13A/Munc13-1 antibody (Cat. #55053-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ALS-associated RNA-binding proteins promote UNC13A transcription through REST downregulation.
A human Staufen1 BAC transgenic mouse exhibits abnormal autophagy and neurodegeneration across the central nervous system.
Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release.
TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy.
Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa.
Watanabe Y, Suzuki N, Nakagawa T, Hosogane M, Akiyama T, Kageyama N, Funayama Y, Warita H, Morimoto S, Okano H, Aoki M, Nakayama K
The EMBO journal 2025 Sep;44(17):4745-4771
The EMBO journal 2025 Sep;44(17):4745-4771
A human Staufen1 BAC transgenic mouse exhibits abnormal autophagy and neurodegeneration across the central nervous system.
Scoles D, Paul S, Nguyen H, Gandelman M, Dansithong W, Figueroa K, Bonini N, Pulst S
Research square 2025 Sep 23;
Research square 2025 Sep 23;
Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release.
Zhang H, Lei M, Zhang Y, Li H, He Z, Xie S, Zhu L, Wang S, Liu J, Li Y, Lu Y, Ma C
Science advances 2024 May 17;10(20):eadi7024
Science advances 2024 May 17;10(20):eadi7024
TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, Mekhoubad S, Sallee N, Mekonnen G, Ganser L, Rubien JD, Jansen-West K, Cook CN, Pickles S, Oskarsson B, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Shorter J, Myong S, Green EM, Seeley WW, Petrucelli L, Gitler AD
Nature 2022 Mar;603(7899):124-130
Nature 2022 Mar;603(7899):124-130
Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy.
Ramos H, Bogdanov P, Huerta J, Deàs-Just A, Hernández C, Simó R
Antioxidants (Basel, Switzerland) 2022 Jul 21;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 21;11(7)
Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Zhou H, Wei Z, Wang S, Yao D, Zhang R, Ma C
Cell reports 2019 Mar 19;26(12):3347-3359.e6
Cell reports 2019 Mar 19;26(12):3347-3359.e6
Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa.
Fan F, Matsunaga K, Wang H, Ishizaki R, Kobayashi E, Kiyonari H, Mukumoto Y, Okunishi K, Izumi T
eLife 2017 Jul 4;6
eLife 2017 Jul 4;6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UNC13A/Munc13-1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human UNC13A/Munc13-1. This antibody recognizes human, mouse antigen. The UNC13A/Munc13-1 antibody has been validated for the following applications: ELISA, WB analysis.
