Antibody data
- Antibody Data
- Antigen structure
- References [68]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- 55131-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Collagen Type IV antibody
- Antibody type
- Polyclonal
- Description
- Collagen Type IV antibody (Cat. #55131-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Angiogenic and Fibrogenic Dual-effect of Gremlin1 on Proliferative Diabetic Retinopathy.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis.
FBN1 knockout promotes cervical artery dissection by inducing N-glycosylation alternation of extracellular matrix proteins in rat VSMCs.
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib.
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Efficacy of Danggui Buxue decoction on diabetic nephropathy-induced renal fibrosis in rats and possible mechanism.
Germline gain-of-function MMP11 variant results in an aggressive form of colorectal cancer.
The kidney antifibrotic effects of 5,7,3',4',5'-pentamethoxyflavone from Bauhinia championii in streptozotocin-induced diabetic rats: in vivo and in vitro experiments.
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Peroxisome Proliferator-Activated Receptor Gene Knockout Promotes Podocyte Injury in Diabetic Mice.
Expression profile analysis to identify potential gene changes induced by dexamethasone in the trabecular meshwork.
Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription.
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis.
Methyl-CpG-binding domain protein 2 contributes to renal fibrosis through promoting polarized M1 macrophages.
Development of a Vascularized Human Skin Equivalent with Hypodermis for Photoaging Studies.
TIPARP is involved in the regulation of intraocular pressure.
Thrombospondin 1 missense alleles induce extracellular matrix protein aggregation and TM dysfunction in congenital glaucoma.
The IRE1/JNK signaling pathway regulates inflammation cytokines and production of glomerular extracellular matrix in the acute kidney injury to chronic kidney disease transition.
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice.
Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.
PPARγ Mediates the Anti-Epithelial-Mesenchymal Transition Effects of FGF1(ΔHBS) in Chronic Kidney Diseases via Inhibition of TGF-β1/SMAD3 Signaling.
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin.
Patterned vascularization in a directional ice-templated scaffold of decellularized matrix.
Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients.
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway.
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms.
Generation of Self-assembled Vascularized Human Skin Equivalents.
circACTR2: A Novel Mechanism Regulating High Glucose-Induced Fibrosis in Renal Tubular Cells via Pyroptosis.
Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation.
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway.
Wogonin Ameliorates Renal Inflammation and Fibrosis by Inhibiting NF-κB and TGF-β1/Smad3 Signaling Pathways in Diabetic Nephropathy.
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
SHCBP1 Promotes Papillary Thyroid Carcinoma Carcinogenesis and Progression Through Promoting Formation of Integrin and Collagen and Maintaining Cell Stemness.
FTY720 Protects Against Ischemia-Reperfusion Injury by Preventing the Redistribution of Tight Junction Proteins and Decreases Inflammation in the Subacute Phase in an Experimental Stroke Model.
Matrisome Provides a Supportive Microenvironment for Skin Functions of Diverse Species.
Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas.
Curcumol may reverse early and advanced liver fibrogenesis through downregulating the uPA/uPAR pathway.
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
USP9X prevents AGEs-induced upregulation of FN and TGF-β1 through activating Nrf2-ARE pathway in rat glomerular mesangial cells.
Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress.
Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats.
Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway.
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca(2+)/CAMK II/ERK/NF-κB signaling pathway.
Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
5-aminoisoquinoline improves renal function and fibrosis during recovery phase of cisplatin-induced acute kidney injury in rats.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy.
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway.
Wu X, Qin B, Cheng R, Zhou R, Wang X, Zhang Z, Mao X, Xie Z, Chen M, Jiang L, Xie P, Ji J, Zhang W, Yuan S, Hu Z, Liu Q
International journal of biological sciences 2024;20(3):897-915
International journal of biological sciences 2024;20(3):897-915
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis.
Zuo T, Xie Q, Liu J, Yang J, Shi J, Kong D, Wang Y, Zhang Z, Gao H, Zeng DB, Wang X, Tao P, Wei W, Wang J, Li Y, Long Q, Li C, Chang L, Ning H, Li Y, Cui C, Ge X, Wu J, Li G, Hong X, Yang X, Dai E, He F, Wu J, Ruan Y, Lu S, Xu P
Gastroenterology 2023 Sep;165(3):746-761.e16
Gastroenterology 2023 Sep;165(3):746-761.e16
FBN1 knockout promotes cervical artery dissection by inducing N-glycosylation alternation of extracellular matrix proteins in rat VSMCs.
Feng X, Zheng X, Lin A, Yang S, Zhang S, Wu D, Wu W, Han X
Cellular signalling 2023 Oct;110:110834
Cellular signalling 2023 Oct;110:110834
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib.
Wang D, Wei Y, Xu L, Zhang J
Advances in rheumatology (London, England) 2023 May 16;63(1):22
Advances in rheumatology (London, England) 2023 May 16;63(1):22
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Zhao X, He X, Wei W, Huang K
European journal of pharmacology 2023 May 15;947:175671
European journal of pharmacology 2023 May 15;947:175671
Efficacy of Danggui Buxue decoction on diabetic nephropathy-induced renal fibrosis in rats and possible mechanism.
Ye Z, Xian W, Ling GU, Zihang LI, Jingtian Z, Wenkai W, Liang Z, Mei X
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Jun;43(3):507-513
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Jun;43(3):507-513
Germline gain-of-function MMP11 variant results in an aggressive form of colorectal cancer.
Martin-Morales L, Manzano S, Rodrigo-Faus M, Vicente-Barrueco A, Lorca V, Núñez-Moreno G, Bragado P, Porras A, Caldes T, Garre P, Gutierrez-Uzquiza A
International journal of cancer 2023 Jan 15;152(2):283-297
International journal of cancer 2023 Jan 15;152(2):283-297
The kidney antifibrotic effects of 5,7,3',4',5'-pentamethoxyflavone from Bauhinia championii in streptozotocin-induced diabetic rats: in vivo and in vitro experiments.
Li J, Huang X, He K, Wu S
Pharmaceutical biology 2023 Dec;61(1):938-948
Pharmaceutical biology 2023 Dec;61(1):938-948
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Hu Z, Zhang Y, Chen J, Luo M, Wang N, Xiao Y, He Q
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y
Cellular signalling 2023 Aug;108:110712
Cellular signalling 2023 Aug;108:110712
Peroxisome Proliferator-Activated Receptor Gene Knockout Promotes Podocyte Injury in Diabetic Mice.
Yan R, Zhang Y, Yang Y, Liu L, Liu L, Guo Z, Yu H, Wang Y, Guo B
BioMed research international 2022;2022:9018379
BioMed research international 2022;2022:9018379
Expression profile analysis to identify potential gene changes induced by dexamethasone in the trabecular meshwork.
Wei M, Chen LM, Huang ZY, Zhang GW, Guan HJ, Ji M
International journal of ophthalmology 2022;15(8):1240-1248
International journal of ophthalmology 2022;15(8):1240-1248
Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription.
Xiong Y, Song X, Kudusi, Zu X, Chen M, He W, Qi L
Functional & integrative genomics 2022 Oct;22(5):937-950
Functional & integrative genomics 2022 Oct;22(5):937-950
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
Feng Y, Zhu G, Chen R, Shi G, Peng M, Zhou Y, Fu W, Zhou P
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis.
Tan X, Banerjee P, Liu X, Yu J, Lee S, Ahn YH, Creighton CJ, Kurie JM
JCI insight 2022 Jan 11;7(1)
JCI insight 2022 Jan 11;7(1)
Methyl-CpG-binding domain protein 2 contributes to renal fibrosis through promoting polarized M1 macrophages.
Ai K, Pan J, Zhang P, Li H, He Z, Zhang H, Li X, Li Y, Yi L, Kang Y, Wang Y, Xiang X, Chai X, Zhang D
Cell death & disease 2022 Feb 8;13(2):125
Cell death & disease 2022 Feb 8;13(2):125
Development of a Vascularized Human Skin Equivalent with Hypodermis for Photoaging Studies.
Sanchez MM, Tonmoy TI, Park BH, Morgan JT
Biomolecules 2022 Dec 7;12(12)
Biomolecules 2022 Dec 7;12(12)
TIPARP is involved in the regulation of intraocular pressure.
Zhang Y, Song M, Bi Y, Lei Y, Sun X, Chen Y
Communications biology 2022 Dec 19;5(1):1386
Communications biology 2022 Dec 19;5(1):1386
Thrombospondin 1 missense alleles induce extracellular matrix protein aggregation and TM dysfunction in congenital glaucoma.
Fu H, Siggs OM, Knight LS, Staffieri SE, Ruddle JB, Birsner AE, Collantes ER, Craig JE, Wiggs JL, D'Amato RJ
The Journal of clinical investigation 2022 Dec 1;132(23)
The Journal of clinical investigation 2022 Dec 1;132(23)
The IRE1/JNK signaling pathway regulates inflammation cytokines and production of glomerular extracellular matrix in the acute kidney injury to chronic kidney disease transition.
Liang Y, Qu L, Liu Z, Liang L, Wang Y, Quan S, Wang Y, Tang L
Molecular biology reports 2022 Aug;49(8):7709-7718
Molecular biology reports 2022 Aug;49(8):7709-7718
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Wakamatsu K, Chiba Y, Murakami R, Matsumoto K, Miyai Y, Kawauchi M, Yanase K, Uemura N, Ueno M
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Shi M, Zhang J, Wang Y, Peng C, Hu H, Qiao M, Zhao X, Chen D
Biomaterials 2022 Apr;283:121448
Biomaterials 2022 Apr;283:121448
The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice.
Yu Y, Liu X, Zhao Z, Xu Z, Qiao Y, Zhou Y, Qiao H, Zhong J, Dai J, Suo G
Frontiers in pharmacology 2021;12:747223
Frontiers in pharmacology 2021;12:747223
Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.
Rong Q, Han B, Li Y, Yin H, Li J, Hou Y
Frontiers in pharmacology 2021;12:729384
Frontiers in pharmacology 2021;12:729384
PPARγ Mediates the Anti-Epithelial-Mesenchymal Transition Effects of FGF1(ΔHBS) in Chronic Kidney Diseases via Inhibition of TGF-β1/SMAD3 Signaling.
Wang D, Zhao T, Zhao Y, Yin Y, Huang Y, Cheng Z, Wang B, Liu S, Pan M, Sun D, Wang Z, Zhu G
Frontiers in pharmacology 2021;12:690535
Frontiers in pharmacology 2021;12:690535
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin.
De Moor L, Smet J, Plovyt M, Bekaert B, Vercruysse C, Asadian M, De Geyter N, Van Vlierberghe S, Dubruel P, Declercq H
Biofabrication 2021 Sep 21;13(4)
Biofabrication 2021 Sep 21;13(4)
Patterned vascularization in a directional ice-templated scaffold of decellularized matrix.
Shen L, Song X, Xu Y, Tian R, Wang Y, Li P, Li J, Bai H, Zhu H, Wang D
Engineering in life sciences 2021 Oct;21(10):683-692
Engineering in life sciences 2021 Oct;21(10):683-692
Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients.
Zhou Z, Liu XQ, Zhang SQ, Qi XM, Zhang Q, Yard B, Wu YG
Amino acids 2021 May;53(5):687-700
Amino acids 2021 May;53(5):687-700
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Liu J, Li X, Lu S, Zheng X, Zhang X, Zhao W
Annals of translational medicine 2021 Mar;9(6):492
Annals of translational medicine 2021 Mar;9(6):492
Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway.
Xiao Y, Deng J, Li C, Gong X, Gui Z, Huang J, Zhang Y, Liu Y, Ye X, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153488
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153488
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms.
Liu K, Zhao X, Qi X, Hou DL, Li HB, Gu YH, Xu QL
European journal of medicinal chemistry 2021 Jun 5;218:113388
European journal of medicinal chemistry 2021 Jun 5;218:113388
Generation of Self-assembled Vascularized Human Skin Equivalents.
Sanchez MM, Morgan JT
Journal of visualized experiments : JoVE 2021 Feb 12;(168)
Journal of visualized experiments : JoVE 2021 Feb 12;(168)
circACTR2: A Novel Mechanism Regulating High Glucose-Induced Fibrosis in Renal Tubular Cells via Pyroptosis.
Wen S, Li S, Li L, Fan Q
Biological & pharmaceutical bulletin 2020;43(3):558-564
Biological & pharmaceutical bulletin 2020;43(3):558-564
Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation.
Zhang Y, Tao C, Xuan C, Jiang J, Cao W
Oxidative medicine and cellular longevity 2020;2020:9542165
Oxidative medicine and cellular longevity 2020;2020:9542165
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, Chen Z, Wang S, Liu J
Oxidative medicine and cellular longevity 2020;2020:6834236
Oxidative medicine and cellular longevity 2020;2020:6834236
Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway.
Li X, Zou Y, Xing J, Fu YY, Wang KY, Wan PZ, Zhai XY
Oxidative medicine and cellular longevity 2020;2020:6286984
Oxidative medicine and cellular longevity 2020;2020:6286984
Wogonin Ameliorates Renal Inflammation and Fibrosis by Inhibiting NF-κB and TGF-β1/Smad3 Signaling Pathways in Diabetic Nephropathy.
Zheng ZC, Zhu W, Lei L, Liu XQ, Wu YG
Drug design, development and therapy 2020;14:4135-4148
Drug design, development and therapy 2020;14:4135-4148
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
Wei J, Wang Y, Qi X, Fan Z, Wu Y
American journal of translational research 2020;12(5):1584-1599
American journal of translational research 2020;12(5):1584-1599
SHCBP1 Promotes Papillary Thyroid Carcinoma Carcinogenesis and Progression Through Promoting Formation of Integrin and Collagen and Maintaining Cell Stemness.
Geng H, Guo M, Xu W, Zang X, Wu T, Teng F, Wang Y, Liu X, Wang X, Sun Q, Liang J
Frontiers in endocrinology 2020;11:613879
Frontiers in endocrinology 2020;11:613879
FTY720 Protects Against Ischemia-Reperfusion Injury by Preventing the Redistribution of Tight Junction Proteins and Decreases Inflammation in the Subacute Phase in an Experimental Stroke Model.
Wang Z, Higashikawa K, Yasui H, Kuge Y, Ohno Y, Kihara A, Midori YA, Houkin K, Kawabori M
Translational stroke research 2020 Oct;11(5):1103-1116
Translational stroke research 2020 Oct;11(5):1103-1116
Matrisome Provides a Supportive Microenvironment for Skin Functions of Diverse Species.
Liu B, Zhang S, Wang W, Yun Z, Lv L, Chai M, Wu Z, Zhu Y, Ma J, Leng L
ACS biomaterials science & engineering 2020 Oct 12;6(10):5720-5733
ACS biomaterials science & engineering 2020 Oct 12;6(10):5720-5733
Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas.
Du J, Liang L, Liu S, Yang X, Cao S, Zhang H, Su H, Gong X, Chen Q, Kong X, Xu D
Clinical and experimental nephrology 2020 Nov;24(11):1007-1014
Clinical and experimental nephrology 2020 Nov;24(11):1007-1014
Curcumol may reverse early and advanced liver fibrogenesis through downregulating the uPA/uPAR pathway.
Li G, Lin J, Peng Y, Qin K, Wen L, Zhao T, Feng Q
Phytotherapy research : PTR 2020 Jun;34(6):1421-1435
Phytotherapy research : PTR 2020 Jun;34(6):1421-1435
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Li L, Xu L, Wen S, Yang Y, Li X, Fan Q
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Tan Y, Li Y, Zhou F, Guo J, Wang T, Shi Y, Yang Y, Lu J, Pei G
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Journal of pharmacological sciences 2020 Jul;143(3):165-175
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Jiang ZH, Tang YZ, Song HN, Yang M, Li B, Ni CL
International journal of molecular medicine 2020 Jan;45(1):45-52
International journal of molecular medicine 2020 Jan;45(1):45-52
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
Xu J, Xiang P, Liu L, Sun J, Ye S
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
Fan Z, Qi X, Yang W, Xia L, Wu Y
Archives of medical research 2020 Aug;51(6):524-534
Archives of medical research 2020 Aug;51(6):524-534
USP9X prevents AGEs-induced upregulation of FN and TGF-β1 through activating Nrf2-ARE pathway in rat glomerular mesangial cells.
Huang K, Zhao X
Experimental cell research 2020 Aug 15;393(2):112100
Experimental cell research 2020 Aug 15;393(2):112100
Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress.
Schwörer S, Berisa M, Violante S, Qin W, Zhu J, Hendrickson RC, Cross JR, Thompson CB
The EMBO journal 2020 Apr 15;39(8):e103334
The EMBO journal 2020 Apr 15;39(8):e103334
Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats.
Zhang Y, Yang J, Zhuan L, Zang G, Wang T, Liu J
PeerJ 2019;7:e7507
PeerJ 2019;7:e7507
Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway.
Ma TK, Xu L, Lu LX, Cao X, Li X, Li LL, Wang X, Fan QL
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2597-2608
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2597-2608
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, Zhu X, Xiang X, Li H, Zhang D
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca(2+)/CAMK II/ERK/NF-κB signaling pathway.
Ding XW, Sun X, Shen XF, Lu Y, Wang JQ, Sun ZR, Miao CH, Chen JW
Acta pharmacologica Sinica 2019 Oct;40(10):1303-1313
Acta pharmacologica Sinica 2019 Oct;40(10):1303-1313
Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy.
Shang J, Wang L, Zhang Y, Zhang S, Ning L, Zhao J, Cheng G, Liu D, Xiao J, Zhao Z
Journal of cellular and molecular medicine 2019 May;23(5):3417-3428
Journal of cellular and molecular medicine 2019 May;23(5):3417-3428
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
Liu L, Li Y, Wang Z, Ding F, Cheng Z, Xu Q, Cai Y, Limbu MH, Yang Y, Liu B, Chen P
Experimental cell research 2018 Sep 15;370(2):198-207
Experimental cell research 2018 Sep 15;370(2):198-207
LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.
Li A, Peng R, Sun Y, Liu H, Peng H, Zhang Z
Cell death & disease 2018 May 1;9(5):461
Cell death & disease 2018 May 1;9(5):461
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Sun JX, Chang TF, Li MH, Sun LJ, Yan XC, Yang ZY, Liu Y, Xu WQ, Lv Y, Su JB, Liang L, Han H, Dou GR, Wang YS
Angiogenesis 2018 Aug;21(3):635-652
Angiogenesis 2018 Aug;21(3):635-652
5-aminoisoquinoline improves renal function and fibrosis during recovery phase of cisplatin-induced acute kidney injury in rats.
Quesada A, O'Valle F, Montoro-Molina S, Gómez-Morales M, Caba-Molina M, González JF, de Gracia MC, Osuna A, Vargas F, Wangensteen R
Bioscience reports 2018 Apr 27;38(2)
Bioscience reports 2018 Apr 27;38(2)
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy.
Yi H, Peng R, Zhang LY, Sun Y, Peng HM, Liu HD, Yu LJ, Li AL, Zhang YJ, Jiang WH, Zhang Z
Cell death & disease 2017 Feb 2;8(2):e2583
Cell death & disease 2017 Feb 2;8(2):e2583
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway.
Li XY, Wang SS, Han Z, Han F, Chang YP, Yang Y, Xue M, Sun B, Chen LM
Molecular therapy. Nucleic acids 2017 Dec 15;9:48-56
Molecular therapy. Nucleic acids 2017 Dec 15;9:48-56
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Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Collagen Type IV antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Collagen Type IV. This antibody recognizes human antigen. The Collagen Type IV antibody has been validated for the following applications: ELISA, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human kidney tissue slide using 55131-1-AP( COL4A2 Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC