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Western blot
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- Antibody Data
- Antigen structure
- References [237]
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- Other assay [29]
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- Product number
- 71-0700 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Connexin 43 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody reacts with connexin 43. On western blots, this antibody detects a 43 kDa protein with mouse brain, rat brain, and human smooth muscle cell extracts. Reactivity with other connexin types has not been observed on western blots (note: samples were not boiled prior to running SDS-PAGE). Positive immunohistostaining is seen with mouse heart and thalamus tissue. Paraffin embedded sections require a heat-induced epitope retrieval (HIER) step. Reactivity of this antibody with connexin 43 is independent of phosphorylation status.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 0.25 mg/mL
- Storage
- -20°C
Submitted references Gap junctions regulate the activity of AgRP neurons and diet-induced obesity in male mice.
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway.
High-resolution 3D fluorescent imaging of intact tissues.
Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing.
Subcellular Localization of Connexin 26 in Cardiomyocytes and in Cardiomyocyte-Derived Extracellular Vesicles.
Desmosomal COP9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Purinergic Receptor Blockade with Suramin Increases Survival of Postnatal Neural Progenitor Cells In Vitro.
3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels.
In vitro Differentiation of Human iPSC-derived Cardiovascular Progenitor Cells (iPSC-CVPCs).
Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function.
Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes.
Ataxia telangiectasia mutated pathway disruption affects hepatic DNA and tissue damage in nonalcoholic fatty liver disease.
Cardiac remodeling and arrhythmogenesis are ameliorated by administration of Cx43 mimetic peptide Gap27 in heart failure rats.
Mitochondrial connexin 43 in sex-dependent myocardial responses and estrogen-mediated cardiac protection following acute ischemia/reperfusion injury.
Connexin 43 maintains tissue polarity and regulates mitotic spindle orientation in the breast epithelium.
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
Mitochondrial Modulation by Dichloroacetate Reduces Toxicity of Aberrant Glial Cells and Gliosis in the SOD1G93A Rat Model of Amyotrophic Lateral Sclerosis.
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing.
Tubulin detyrosination promotes human trophoblast syncytium formation.
Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress.
C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats.
Loss of connexin43 in murine Sertoli cells and its effect on blood-testis barrier formation and dynamics.
An improved method for increasing the efficiency of gene transfection and transduction.
Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles.
Inflammatory activation of human cardiac fibroblasts leads to altered calcium signaling, decreased connexin 43 expression and increased glutamate secretion.
Electronic Cigarette Smoke Impairs Normal Mesenchymal Stem Cell Differentiation.
Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na(+) channel function.
Establishment, maintenance and functional integrity of the blood-testis barrier in organotypic cultures of fresh and frozen/thawed prepubertal mouse testes.
Connexin36 localization to pinealocytes in the pineal gland of mouse and rat.
Immunofluorescence reveals unusual patterns of labelling for connexin43 localized to calbindin-D28K-positive interstitial cells in the pineal gland.
Osteogenic differentiation capacity of human mesenchymal stromal cells in response to extracellular calcium with special regard to connexin 43.
In vitro formation of neuroclusters in microfluidic devices and cell migration as a function of stromal-derived growth factor 1 gradients.
Comparison of cardiac stem cell sheets detached by Versene solution and from thermoresponsive dishes reveals similar properties of constructs.
Mitochondrial connexin40 regulates mitochondrial calcium uptake in coronary endothelial cells.
Ouabain Modulates the Distribution of Connexin 43 in Epithelial Cells.
Polyglucosan Molecules Induce Mitochondrial Impairment and Apoptosis in Germ Cells Without Affecting the Integrity and Functionality of Sertoli Cells.
Engineering prokaryotic channels for control of mammalian tissue excitability.
Human Organotypic Cultured Cardiac Slices: New Platform For High Throughput Preclinical Human Trials.
Phosphorylation at Connexin43 Serine-368 Is Necessary for Myocardial Conduction During Metabolic Stress.
GnRH Episodic Secretion Is Altered by Pharmacological Blockade of Gap Junctions: Possible Involvement of Glial Cells.
Expression and Localization of Connexins in the Outer Retina of the Mouse.
Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice.
Connexin 50 modulates Sox2 expression in spinal-cord-derived ependymal stem/progenitor cells.
Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury.
Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.
Anti-arrhythmic effects of atrial ganglionated plexi stimulation is accompanied by preservation of connexin43 protein in ischemia-reperfusion canine model.
Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.
Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin.
Voltage-dependent K+ currents contribute to heterogeneity of olfactory ensheathing cells.
Tanshinone IIA enhances bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in nuclei and mitochondria.
Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion.
Primary tumor- and metastasis-derived colon cancer cells differently modulate connexin expression and function in human capillary endothelial cells.
Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.
Knockdown of connexin 43 attenuates balloon injury-induced vascular restenosis through the inhibition of the proliferation and migration of vascular smooth muscle cells.
Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction.
Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1.
Functional properties of a Brazilian derived mouse embryonic stem cell line.
Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland.
Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease.
Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract.
Lentivirus-mediated RNAi knockdown of the gap junction protein, Cx43, attenuates the development of vascular restenosis following balloon injury.
Long-distance communication between laryngeal carcinoma cells.
Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL).
Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus.
Does diabetes affect the distribution and number of interstitial cells and neuronal tissue in the ureter, bladder, prostate, and urethra of humans?
Connexins modulate autophagosome biogenesis.
Reduced connexin 43 in eutopic endometrium and cultured endometrial stromal cells from subjects with endometriosis.
HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.
Mutation of human connexin43 amino acids s279/s282 increases protein stability upon treatment with epidermal growth factor.
Rapid manifestation of reactive astrogliosis in acute hippocampal brain slices.
Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels.
Implanted neural progenitor cells regulate glial reaction to brain injury and establish gap junctions with host glial cells.
Connexin 30 sets synaptic strength by controlling astroglial synapse invasion.
Both PKA and Epac pathways mediate N-acetylcysteine-induced Connexin43 preservation in rats with myocardial infarction.
Tanshinone IIA increases the bystander effect of herpes simplex virus thymidine kinase/ganciclovir gene therapy via enhanced gap junctional intercellular communication.
Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature.
Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype.
Epigallocatechin-3-gallate-mediated cardioprotection by Akt/GSK-3β/caveolin signalling in H9c2 rat cardiomyoblasts.
Connexin-43 hemichannels contribute to the propagation of μ-calpain-mediated neuronal death in a cortical ablation injury model.
Absence of venous valves in mice lacking Connexin37.
Striatal allografts in patients with Huntington's disease: impact of diminished astrocytes and vascularization on graft viability.
Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signaling.
Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy.
Blocking of connexin-mediated communication promotes neuroprotection during acute degeneration induced by mechanical trauma.
Connexin and AMPA receptor expression changes over time in the rat olfactory bulb.
Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.
Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells.
Prostaglandin-induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins.
Neuronal gap junction coupling is regulated by glutamate and plays critical role in cell death during neuronal injury.
Cardiac effects of osteostatin in mice.
Reduced connexin43 expression correlates with c-Src activation, proliferation, and glucose uptake in reactive astrocytes after an excitotoxic insult.
K ATP channel agonists preserve connexin43 protein in infarcted rats by a protein kinase C-dependent pathway.
Age-related changes in rat bone-marrow mesenchymal stem cell plasticity.
Gap junctions and hydrogen peroxide are involved in endothelium-derived hyperpolarising responses to bradykinin in omental arteries and veins isolated from pregnant women.
Residual Cx45 and its relationship to Cx43 in murine ventricular myocardium.
Epidermal differentiation and loss of clonal growth potential of human limbal basal epithelial progenitor cells during intrastromal invasion.
Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity.
Reduced gap junctional communication among astrocytes in experimental diabetes: contributions of altered connexin protein levels and oxidative-nitrosative modifications.
Ablation of connexin30 in transgenic mice alters expression patterns of connexin26 and connexin32 in glial cells and leptomeninges.
Focal adhesion kinase modulates radial glia-dependent neuronal migration through connexin-26.
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
Interplay of chemical neurotransmitters regulates developmental increase in electrical synapses.
Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion.
Restraint stress induces connexin-43 translocation via α-adrenoceptors in rat heart.
Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development.
Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice.
Hyperglycaemia and diabetes impair gap junctional communication among astrocytes.
17beta-Estradiol decreases vulnerability to ventricular arrhythmias by preserving connexin43 protein in infarcted rats.
Reorganization of gap junctions after focused ultrasound blood-brain barrier opening in the rat brain.
Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment.
Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.
Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43.
Cyclic stretch downregulates arterial vascular connexin43 protein expression: an ex vivo study.
Olfactory ensheathing cell membrane properties are shaped by connectivity.
Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection.
Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues.
Ischemia enhances translocation of connexin43 and gap junction intercellular communication, thereby propagating contraction band necrosis after reperfusion.
Ischemia enhances translocation of connexin43 and gap junction intercellular communication, thereby propagating contraction band necrosis after reperfusion.
Expression of connexins in normal and neoplastic canine bone tissue.
Replacement of connexin 43 by connexin 32 in a knock-in mice model attenuates aortic endothelium-derived hyperpolarizing factor-mediated relaxation.
Myocardin is required for cardiomyocyte survival and maintenance of heart function.
Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality.
Evidence against a role of gap junctions in vestibular compensation.
Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.
Tyrosine-dependent basolateral targeting of human connexin43-eYFP in Madin-Darby canine kidney cells can be disrupted by the oculodentodigital dysplasia mutation L90V.
Eps15 interacts with ubiquitinated Cx43 and mediates its internalization.
Unique expression of connexins in the human cochlea.
Cx43 contributes to TGF-beta signaling to regulate differentiation of cardiac fibroblasts into myofibroblasts.
Taurine suppresses the spread of cell death in electrically coupled RPE cells.
Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes.
Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1.
Differential expression of connexins during histogenesis of the chick retina.
Novel mutations in GJA1 cause oculodentodigital syndrome.
Effects of 18-glycyrrhetinic acid on serine 368 phosphorylation of connexin43 in rat neonatal cardiomyocytes.
No impact of protein phosphatases on connexin 43 phosphorylation in ischemic preconditioning.
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.
Altered expression of connexin43 contributes to the arrhythmogenic substrate during the development of heart failure in cardiomyopathic hamster.
Expression of matrix metalloproteinases, cytokines, and connexins in diabetic and nondiabetic human keratinocytes before and after transplantation into an ex vivo wound-healing model.
Gap junctional intercellular communication is required to maintain embryonic stem cells in a non-differentiated and proliferative state.
Impact of ultraviolet radiation on the expression of marker proteins of gap and adhesion junctions in human epidermis.
Limited intravascular coupling in the rodent brainstem and retina supports a role for glia in regional blood flow.
Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival.
Immunoreactivity for the GABAA receptor alpha1 subunit, somatostatin and Connexin36 distinguishes axoaxonic, basket, and bistratified interneurons of the rat hippocampus.
Repeated simulated ischemia and protection against gap junctional uncoupling.
Connexin40 regulates renin production and blood pressure.
The in vitro behaviour and patterns of colony formation of murine epithelial stem cells.
Biphasic regulation of AP-1 subunits during human epidermal wound healing.
The proteasome regulates the interaction between Cx43 and ZO-1.
Downregulation of connexin40 and increased prevalence of atrial arrhythmias in transgenic mice with cardiac-restricted overexpression of tumor necrosis factor.
Changes in phosphorylation of connexin43 in rats during acute myocardial hypoxia and effects of antiarrhythmic peptide on the phosphorylation.
Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus.
Gap junctional intercellular communication capacity by gap-FRAP technique: a comparative study.
Temporal profile of connexin 43 expression after photothrombotic lesion in rat brain.
Modulation of connexin expression and gap junction communication in astrocytes by the gram-positive bacterium S. aureus.
18beta-glycyrrhetinic acid promotes src interaction with connexin43 in rat cardiomyocytes.
Aconitine alters connexin43 phosphorylation status and [Ca2+] oscillation patterns in cultured ventricular myocytes of neonatal rats.
Gap junction adhesion is necessary for radial migration in the neocortex.
Pressure induces loss of gap junction communication and redistribution of connexin 43 in astrocytes.
Dual regulation of astrocyte gap junction hemichannels by growth factors and a pro-inflammatory cytokine via the mitogen-activated protein kinase cascade.
Ubiquitin protein ligase Nedd4 binds to connexin43 by a phosphorylation-modulated process.
Reduction and redistribution of gap and adherens junction proteins after ischemia and reperfusion.
Expression of connexins 36, 43, and 45 during postnatal development of the mouse retina.
Spatial separation of endothelial small- and intermediate-conductance calcium-activated potassium channels (K(Ca)) and connexins: possible relationship to vasodilator function?
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue.
Prolonged dark adaptation changes connexin expression in the mouse retina.
GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function.
Altered expression of connexin subtypes in mesial temporal lobe epilepsy in humans.
Overexpression of cardiac connexin45 increases susceptibility to ventricular tachyarrhythmias in vivo.
Cardiac cells implanted within the outer aortic wall of rats generate measurable contractile force.
Gap junctional coupling and connexin immunoreactivity in rabbit retinal glia.
G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis.
Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis.
Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation.
Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation.
The TLR3 ligand polyI: C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the NF-kappaB and PI3 kinase pathways.
Redistribution of connexin43 in regional acute ischemic myocardium: influence of ischemic preconditioning.
Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin.
Phosphorylation of the gap junction protein Connexin43 in CIN III lesions and cervical carcinomas.
Connexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning.
Expression of connexins 26 and 43 in canine hyperplastic and neoplastic mammary glands.
Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb.
Drebrin, an actin-binding, cell-type characteristic protein: induction and localization in epithelial skin tumors and cultured keratinocytes.
Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions.
The phosphorylated form of connexin43 is up-regulated in breast hyperplasias and carcinomas and in their neoformed capillaries.
Augmentation of differentiation and gap junction function by kaempferol in partially differentiated colon cancer cells.
Matrix-protein-specific regulation of Cx43 expression in cardiac myocytes subjected to mechanical load.
Epithelial-mesenchymal transition in colonies of rhesus monkey embryonic stem cells: a model for processes involved in gastrulation.
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
Efferent vagal nerve stimulation protects heart against ischemia-induced arrhythmias by preserving connexin43 protein.
Functional organization of the bovine rumen epithelium.
Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion.
Postnatal development of GFAP, connexin43 and connexin30 in cat visual cortex.
Distinct pathways regulate expression of cardiac electrical and mechanical junction proteins in response to stretch.
Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning.
Differential expression and localisation of connexin-37 and connexin-43 in follicles of different stages in the 4-week-old mouse ovary.
Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation.
Connexin47, connexin29 and connexin32 co-expression in oligodendrocytes and Cx47 association with zonula occludens-1 (ZO-1) in mouse brain.
17beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor.
2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studies.
Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healing.
Regulation of purified and reconstituted connexin 43 hemichannels by protein kinase C-mediated phosphorylation of Serine 368.
Four classes of intercellular channels between glial cells in the CNS.
Ischemic preconditioning protects against gap junctional uncoupling in cardiac myofibroblasts.
Ischemic preconditioning protects against gap junctional uncoupling in cardiac myofibroblasts.
Effects of cellular cardiomyoplasty on ventricular remodeling assessed by Doppler echocardiography and topographic immunohistochemistry.
Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model.
Implantation of immature neonatal cardiac cells into the wall of the aorta in rats: a novel model for studying morphological and functional development of heart cells in an extracardiac environment.
Structural and molecular pathology of the heart in Carvajal syndrome.
The vascular endothelial growth factor-induced disruption of gap junctions is relayed by an autocrine communication via ATP release in coronary capillary endothelium.
Connexin29 and connexin32 at oligodendrocyte and astrocyte gap junctions and in myelin of the mouse central nervous system.
ECM-induced gap junctional communication enhances mammary epithelial cell differentiation.
Signaling at the gliovascular interface.
Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases.
Role of catenins in the development of gap junctions in rat cardiomyocytes.
Differential expression of connexin 43 in the chick tangential vestibular nucleus.
Phosphorylation and subcellular distribution of connexin43 in normal and stressed cells.
Uterine leiomyomas express myometrial contractile-associated proteins involved in pregnancy-related hormone signaling.
Connexin immunoreactivity in glial cells of the rat retina.
Coupling of astrocyte connexins Cx26, Cx30, Cx43 to oligodendrocyte Cx29, Cx32, Cx47: Implications from normal and connexin32 knockout mice.
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Regulation of gap junction protein (connexin) genes and function in differentiating ES cells.
Anticonvulsant actions of gap junctional blockers in an in vitro seizure model.
Anticonvulsant actions of gap junctional blockers in an in vitro seizure model.
Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions.
Microglia and astrocytes may participate in the shaping of visual callosal projections during postnatal development.
Microglia and astrocytes may participate in the shaping of visual callosal projections during postnatal development.
Expression of connexin43 in mouse Leydig, Sertoli, and germinal cells at different stages of postnatal development.
Developmental regulation of connexin 43 expression in fetal mouse testicular cells.
Activation of fibres in rat sciatic nerve alters phosphorylation state of connexin-43 at astrocytic gap junctions in spinal cord: evidence for junction regulation by neuronal-glial interactions.
Activation of fibres in rat sciatic nerve alters phosphorylation state of connexin-43 at astrocytic gap junctions in spinal cord: evidence for junction regulation by neuronal-glial interactions.
The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction.
Growth hormone increases connexin-43 expression in the cerebral cortex and hypothalamus.
Connexin43 phosphorylation state and intercellular communication in cultured astrocytes following hypoxia and protein phosphatase inhibition.
Connexin43 phosphorylation state and intercellular communication in cultured astrocytes following hypoxia and protein phosphatase inhibition.
Connexin 26 expression and extensive gap junctional coupling in cultures of GT1-7 cells secreting gonadotropin-releasing hormone.
Identification of gap junctional connexin-32 mRNA and protein in gonadotropin-releasing hormone neurons of the female rat.
de Souza GO, Chaves FM, Silva JN, Pedroso JAB, Metzger M, Frazão R, Donato J
The Journal of endocrinology 2022 Nov 1;255(2):75-90
The Journal of endocrinology 2022 Nov 1;255(2):75-90
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway.
Dang R, Wang M, Li X, Wang H, Liu L, Wu Q, Zhao J, Ji P, Zhong L, Licinio J, Xie P
Journal of neuroinflammation 2022 Feb 7;19(1):41
Journal of neuroinflammation 2022 Feb 7;19(1):41
High-resolution 3D fluorescent imaging of intact tissues.
El-Nachef D, Martinson AM, Yang X, Murry CE, MacLellan WR
International journal of cardiology and cardiovascular diseases 2021;1(1):1-14
International journal of cardiology and cardiovascular diseases 2021;1(1):1-14
Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing.
Nardin C, Peres C, Putti S, Orsini T, Colussi C, Mazzarda F, Raspa M, Scavizzi F, Salvatore AM, Chiani F, Tettey-Matey A, Kuang Y, Yang G, Retamal MA, Mammano F
Cancers 2021 Oct 10;13(20)
Cancers 2021 Oct 10;13(20)
Subcellular Localization of Connexin 26 in Cardiomyocytes and in Cardiomyocyte-Derived Extracellular Vesicles.
Falleni A, Moscato S, Sabbatini ARM, Bernardeschi M, Bianchi F, Cecchettini A, Mattii L
Molecules (Basel, Switzerland) 2021 Nov 6;26(21)
Molecules (Basel, Switzerland) 2021 Nov 6;26(21)
Desmosomal COP9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Liang Y, Lyon RC, Pellman J, Bradford WH, Lange S, Bogomolovas J, Dalton ND, Gu Y, Bobar M, Lee MH, Iwakuma T, Nigam V, Asimaki A, Scheinman M, Peterson KL, Sheikh F
The Journal of clinical investigation 2021 Jun 1;131(11)
The Journal of clinical investigation 2021 Jun 1;131(11)
Purinergic Receptor Blockade with Suramin Increases Survival of Postnatal Neural Progenitor Cells In Vitro.
Herrera A, Morcuende S, Talaverón R, Benítez-Temiño B, Pastor AM, Matarredona ER
International journal of molecular sciences 2021 Jan 12;22(2)
International journal of molecular sciences 2021 Jan 12;22(2)
3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels.
Daly AC, Davidson MD, Burdick JA
Nature communications 2021 Feb 2;12(1):753
Nature communications 2021 Feb 2;12(1):753
In vitro Differentiation of Human iPSC-derived Cardiovascular Progenitor Cells (iPSC-CVPCs).
D'Antonio-Chronowska A, D'Antonio M, Frazer KA
Bio-protocol 2020 Sep 20;10(18):e3755
Bio-protocol 2020 Sep 20;10(18):e3755
Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function.
Zhang J, Vincent KP, Peter AK, Klos M, Cheng H, Huang SM, Towne JK, Ferng D, Gu Y, Dalton ND, Chan Y, Li R, Peterson KL, Chen J, McCulloch AD, Knowlton KU, Ross RS
Circulation research 2020 Jul 3;127(2):284-297
Circulation research 2020 Jul 3;127(2):284-297
Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes.
Martins-Marques T, Ribeiro-Rodrigues T, de Jager SC, Zuzarte M, Ferreira C, Cruz P, Reis L, Baptista R, Gonçalves L, Sluijter JP, Girao H
Life science alliance 2020 Dec;3(12)
Life science alliance 2020 Dec;3(12)
Ataxia telangiectasia mutated pathway disruption affects hepatic DNA and tissue damage in nonalcoholic fatty liver disease.
Viswanathan P, Sharma Y, Maisuradze L, Tchaikovskaya T, Gupta S
Experimental and molecular pathology 2020 Apr;113:104369
Experimental and molecular pathology 2020 Apr;113:104369
Cardiac remodeling and arrhythmogenesis are ameliorated by administration of Cx43 mimetic peptide Gap27 in heart failure rats.
Lucero CM, Andrade DC, Toledo C, Díaz HS, Pereyra KV, Diaz-Jara E, Schwarz KG, Marcus NJ, Retamal MA, Quintanilla RA, Del Rio R
Scientific reports 2020 Apr 23;10(1):6878
Scientific reports 2020 Apr 23;10(1):6878
Mitochondrial connexin 43 in sex-dependent myocardial responses and estrogen-mediated cardiac protection following acute ischemia/reperfusion injury.
Wang M, Smith K, Yu Q, Miller C, Singh K, Sen CK
Basic research in cardiology 2019 Nov 18;115(1):1
Basic research in cardiology 2019 Nov 18;115(1):1
Connexin 43 maintains tissue polarity and regulates mitotic spindle orientation in the breast epithelium.
Bazzoun D, Adissu HA, Wang L, Urazaev A, Tenvooren I, Fostok SF, Chittiboyina S, Sturgis J, Hodges K, Chandramouly G, Vidi PA, Talhouk RS, Lelièvre SA
Journal of cell science 2019 May 16;132(10)
Journal of cell science 2019 May 16;132(10)
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
Roberts JD, Murphy NP, Hamilton RM, Lubbers ER, James CA, Kline CF, Gollob MH, Krahn AD, Sturm AC, Musa H, El-Refaey M, Koenig S, Aneq MÅ, Hoorntje ET, Graw SL, Davies RW, Rafiq MA, Koopmann TT, Aafaqi S, Fatah M, Chiasson DA, Taylor MR, Simmons SL, Han M, van Opbergen CJ, Wold LE, Sinagra G, Mittal K, Tichnell C, Murray B, Codima A, Nazer B, Nguyen DT, Marcus FI, Sobriera N, Lodder EM, van den Berg MP, Spears DA, Robinson JF, Ursell PC, Green AK, Skanes AC, Tang AS, Gardner MJ, Hegele RA, van Veen TA, Wilde AA, Healey JS, Janssen PM, Mestroni L, van Tintelen JP, Calkins H, Judge DP, Hund TJ, Scheinman MM, Mohler PJ
The Journal of clinical investigation 2019 Jul 2;129(8):3171-3184
The Journal of clinical investigation 2019 Jul 2;129(8):3171-3184
Mitochondrial Modulation by Dichloroacetate Reduces Toxicity of Aberrant Glial Cells and Gliosis in the SOD1G93A Rat Model of Amyotrophic Lateral Sclerosis.
Martínez-Palma L, Miquel E, Lagos-Rodríguez V, Barbeito L, Cassina A, Cassina P
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2019 Jan;16(1):203-215
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2019 Jan;16(1):203-215
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing.
Végh AMD, den Haan AD, Cócera Ortega L, Verkerk AO, Sluijter JPG, Bakker D, van Amersfoorth S, van Veen TAB, Klerk M, Seppen J, de Bakker JMT, Christoffels VM, Geerts D, Goumans MJTH, Tan HL, Boink GJJ
Molecules (Basel, Switzerland) 2019 Jan 5;24(1)
Molecules (Basel, Switzerland) 2019 Jan 5;24(1)
Tubulin detyrosination promotes human trophoblast syncytium formation.
Wang R, Yu R, Zhu C, Lin HY, Lu X, Wang H
Journal of molecular cell biology 2019 Dec 23;11(11):967-978
Journal of molecular cell biology 2019 Dec 23;11(11):967-978
Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress.
van Opbergen CJM, Noorman M, Pfenniger A, Copier JS, Vermij SH, Li Z, van der Nagel R, Zhang M, de Bakker JMT, Glass AM, Mohler PJ, Taffet SM, Vos MA, van Rijen HVM, Delmar M, van Veen TAB
International journal of molecular sciences 2019 Aug 21;20(17)
International journal of molecular sciences 2019 Aug 21;20(17)
C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats.
Dergilev K, Tsokolaeva Z, Makarevich P, Beloglazova I, Zubkova E, Boldyreva M, Ratner E, Dyikanov D, Menshikov M, Ovchinnikov A, Ageev F, Parfyonova Y
BioMed research international 2018;2018:3536854
BioMed research international 2018;2018:3536854
Loss of connexin43 in murine Sertoli cells and its effect on blood-testis barrier formation and dynamics.
Hollenbach J, Jung K, Noelke J, Gasse H, Pfarrer C, Koy M, Brehm R
PloS one 2018;13(6):e0198100
PloS one 2018;13(6):e0198100
An improved method for increasing the efficiency of gene transfection and transduction.
Shi B, Xue M, Wang Y, Wang Y, Li D, Zhao X, Li X
International journal of physiology, pathophysiology and pharmacology 2018;10(2):95-104
International journal of physiology, pathophysiology and pharmacology 2018;10(2):95-104
Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles.
Li G, Khandekar A, Yin T, Hicks SC, Guo Q, Takahashi K, Lipovsky CE, Brumback BD, Rao PK, Weinheimer CJ, Rentschler SL
Journal of molecular and cellular cardiology 2018 Oct;123:92-107
Journal of molecular and cellular cardiology 2018 Oct;123:92-107
Inflammatory activation of human cardiac fibroblasts leads to altered calcium signaling, decreased connexin 43 expression and increased glutamate secretion.
Skiöldebrand E, Lundqvist A, Björklund U, Sandstedt M, Lindahl A, Hansson E, Hultén LM
Heliyon 2017 Oct;3(10):e00406
Heliyon 2017 Oct;3(10):e00406
Electronic Cigarette Smoke Impairs Normal Mesenchymal Stem Cell Differentiation.
Shaito A, Saliba J, Husari A, El-Harakeh M, Chhouri H, Hashem Y, Shihadeh A, El-Sabban M
Scientific reports 2017 Oct 27;7(1):14281
Scientific reports 2017 Oct 27;7(1):14281
Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na(+) channel function.
Nassal MMJ, Wan X, Dale Z, Deschênes I, Wilson LD, Piktel JS
American journal of physiology. Heart and circulatory physiology 2017 May 1;312(5):H886-H895
American journal of physiology. Heart and circulatory physiology 2017 May 1;312(5):H886-H895
Establishment, maintenance and functional integrity of the blood-testis barrier in organotypic cultures of fresh and frozen/thawed prepubertal mouse testes.
Rondanino C, Maouche A, Dumont L, Oblette A, Rives N
Molecular human reproduction 2017 May 1;23(5):304-320
Molecular human reproduction 2017 May 1;23(5):304-320
Connexin36 localization to pinealocytes in the pineal gland of mouse and rat.
Wang SG, Tsao DD, Vanderpool KG, Yasumura T, Rash JE, Nagy JI
The European journal of neuroscience 2017 Jun;45(12):1594-1605
The European journal of neuroscience 2017 Jun;45(12):1594-1605
Immunofluorescence reveals unusual patterns of labelling for connexin43 localized to calbindin-D28K-positive interstitial cells in the pineal gland.
Tsao DD, Wang SG, Lynn BD, Nagy JI
The European journal of neuroscience 2017 Jun;45(12):1553-1569
The European journal of neuroscience 2017 Jun;45(12):1553-1569
Osteogenic differentiation capacity of human mesenchymal stromal cells in response to extracellular calcium with special regard to connexin 43.
Wagner AS, Glenske K, Wolf V, Fietz D, Mazurek S, Hanke T, Moritz A, Arnhold S, Wenisch S
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2017 Jan;209:18-24
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2017 Jan;209:18-24
In vitro formation of neuroclusters in microfluidic devices and cell migration as a function of stromal-derived growth factor 1 gradients.
McCutcheon S, Unachukwu U, Thakur A, Majeska R, Redenti S, Vazquez M
Cell adhesion & migration 2017 Jan 2;11(1):1-12
Cell adhesion & migration 2017 Jan 2;11(1):1-12
Comparison of cardiac stem cell sheets detached by Versene solution and from thermoresponsive dishes reveals similar properties of constructs.
Dergilev KV, Makarevich PI, Tsokolaeva ZI, Boldyreva MA, Beloglazova IB, Zubkova ES, Menshikov MY, Parfyonova YV
Tissue & cell 2017 Feb;49(1):64-71
Tissue & cell 2017 Feb;49(1):64-71
Mitochondrial connexin40 regulates mitochondrial calcium uptake in coronary endothelial cells.
Guo R, Si R, Scott BT, Makino A
American journal of physiology. Cell physiology 2017 Apr 1;312(4):C398-C406
American journal of physiology. Cell physiology 2017 Apr 1;312(4):C398-C406
Ouabain Modulates the Distribution of Connexin 43 in Epithelial Cells.
Ponce A, Larre I, Castillo A, Flores-Maldonado C, Verdejo-Torres O, Contreras RG, Cereijido M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(4):1329-38
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(4):1329-38
Polyglucosan Molecules Induce Mitochondrial Impairment and Apoptosis in Germ Cells Without Affecting the Integrity and Functionality of Sertoli Cells.
Villarroel-Espíndola F, Tapia C, González-Stegmaier R, Concha II, Slebe JC
Journal of cellular physiology 2016 Oct;231(10):2142-52
Journal of cellular physiology 2016 Oct;231(10):2142-52
Engineering prokaryotic channels for control of mammalian tissue excitability.
Nguyen HX, Kirkton RD, Bursac N
Nature communications 2016 Oct 18;7:13132
Nature communications 2016 Oct 18;7:13132
Human Organotypic Cultured Cardiac Slices: New Platform For High Throughput Preclinical Human Trials.
Kang C, Qiao Y, Li G, Baechle K, Camelliti P, Rentschler S, Efimov IR
Scientific reports 2016 Jun 30;6:28798
Scientific reports 2016 Jun 30;6:28798
Phosphorylation at Connexin43 Serine-368 Is Necessary for Myocardial Conduction During Metabolic Stress.
Nassal MM, Werdich AA, Wan X, Hoshi M, Deschênes I, Rosenbaum DS, Donahue JK
Journal of cardiovascular electrophysiology 2016 Jan;27(1):110-9
Journal of cardiovascular electrophysiology 2016 Jan;27(1):110-9
GnRH Episodic Secretion Is Altered by Pharmacological Blockade of Gap Junctions: Possible Involvement of Glial Cells.
Pinet-Charvet C, Geller S, Desroziers E, Ottogalli M, Lomet D, Georgelin C, Tillet Y, Franceschini I, Vaudin P, Duittoz A
Endocrinology 2016 Jan;157(1):304-22
Endocrinology 2016 Jan;157(1):304-22
Expression and Localization of Connexins in the Outer Retina of the Mouse.
Bolte P, Herrling R, Dorgau B, Schultz K, Feigenspan A, Weiler R, Dedek K, Janssen-Bienhold U
Journal of molecular neuroscience : MN 2016 Feb;58(2):178-92
Journal of molecular neuroscience : MN 2016 Feb;58(2):178-92
Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice.
Choi SR, Roh DH, Yoon SY, Kwon SG, Choi HS, Han HJ, Beitz AJ, Lee JH
Neuropharmacology 2016 Dec;111:34-46
Neuropharmacology 2016 Dec;111:34-46
Connexin 50 modulates Sox2 expression in spinal-cord-derived ependymal stem/progenitor cells.
Rodriguez-Jimenez FJ, Alastrue A, Stojkovic M, Erceg S, Moreno-Manzano V
Cell and tissue research 2016 Aug;365(2):295-307
Cell and tissue research 2016 Aug;365(2):295-307
Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury.
Lee-Kubli CA, Ingves M, Henry KW, Shiao R, Collyer E, Tuszynski MH, Campana WM
Experimental neurology 2016 Apr;278:91-104
Experimental neurology 2016 Apr;278:91-104
Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.
Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM
Developmental biology 2016 Apr 15;412(2):173-90
Developmental biology 2016 Apr 15;412(2):173-90
Anti-arrhythmic effects of atrial ganglionated plexi stimulation is accompanied by preservation of connexin43 protein in ischemia-reperfusion canine model.
Wang S, Li H, Yu L, Chen M, Wang Z, Huang B, Zhou L, Zhou X, Jiang H
International journal of clinical and experimental medicine 2015;8(12):22098-107
International journal of clinical and experimental medicine 2015;8(12):22098-107
Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.
Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K
PloS one 2015;10(8):e0136952
PloS one 2015;10(8):e0136952
Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin.
Fontes JD, Ramsey J, Polk JM, Koop A, Denisova JV, Belousov AB
PloS one 2015;10(5):e0125395
PloS one 2015;10(5):e0125395
Voltage-dependent K+ currents contribute to heterogeneity of olfactory ensheathing cells.
Rela L, Piantanida AP, Bordey A, Greer CA
Glia 2015 Sep;63(9):1646-59
Glia 2015 Sep;63(9):1646-59
Tanshinone IIA enhances bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in nuclei and mitochondria.
Jiang H, Zhao L, Dong X, He A, Zheng C, Johansson M, Karlsson A, Zheng X
Oncology reports 2015 Sep;34(3):1487-93
Oncology reports 2015 Sep;34(3):1487-93
Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion.
Liu L, Li CJ, Lu Y, Zong XG, Luo C, Sun J, Guo LJ
Scientific reports 2015 Sep 28;5:14474
Scientific reports 2015 Sep 28;5:14474
Primary tumor- and metastasis-derived colon cancer cells differently modulate connexin expression and function in human capillary endothelial cells.
Thuringer D, Berthenet K, Cronier L, Solary E, Garrido C
Oncotarget 2015 Oct 6;6(30):28800-15
Oncotarget 2015 Oct 6;6(30):28800-15
Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.
Basheer WA, Harris BS, Mentrup HL, Abreha M, Thames EL, Lea JB, Swing DA, Copeland NG, Jenkins NA, Price RL, Matesic LE
Journal of molecular and cellular cardiology 2015 Nov;88:1-13
Journal of molecular and cellular cardiology 2015 Nov;88:1-13
Knockdown of connexin 43 attenuates balloon injury-induced vascular restenosis through the inhibition of the proliferation and migration of vascular smooth muscle cells.
Han XJ, He D, Xu LJ, Chen M, Wang YQ, Feng JG, Wei MJ, Hong T, Jiang LP
International journal of molecular medicine 2015 Nov;36(5):1361-8
International journal of molecular medicine 2015 Nov;36(5):1361-8
Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction.
Zhang D, Zhu L, Li C, Mu J, Fu Y, Zhu Q, Zhou Z, Liu P, Han C
Basic research in cardiology 2015 May;110(3):28
Basic research in cardiology 2015 May;110(3):28
Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1.
Swager SA, Delfín DA, Rastogi N, Wang H, Canan BD, Fedorov VV, Mohler PJ, Kilic A, Higgins RSD, Ziolo MT, Janssen PML, Rafael-Fortney JA
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2015 May-Jun;24(3):160-167
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2015 May-Jun;24(3):160-167
Functional properties of a Brazilian derived mouse embryonic stem cell line.
Vairo L, Medei E, Dos Santos DS, Rodrigues DC, Goldenberg RC, De Carvalho AC
Anais da Academia Brasileira de Ciencias 2015 Mar;87(1):275-88
Anais da Academia Brasileira de Ciencias 2015 Mar;87(1):275-88
Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland.
Mroue R, Inman J, Mott J, Budunova I, Bissell MJ
Developmental biology 2015 Mar 1;399(1):15-26
Developmental biology 2015 Mar 1;399(1):15-26
Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease.
Fontes MS, Papazova DA, van Koppen A, de Jong S, Korte SM, Bongartz LG, Nguyen TQ, Bierhuizen MF, de Boer TP, van Veen TA, Verhaar MC, Joles JA, van Rijen HV
Cardiorenal medicine 2015 Jun;5(3):208-18
Cardiorenal medicine 2015 Jun;5(3):208-18
Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract.
Liu K, Lyu L, Chin D, Gao J, Sun X, Shang F, Caceres A, Chang ML, Rowan S, Peng J, Mathias R, Kasahara H, Jiang S, Taylor A
Proceedings of the National Academy of Sciences of the United States of America 2015 Jan 27;112(4):1071-6
Proceedings of the National Academy of Sciences of the United States of America 2015 Jan 27;112(4):1071-6
Lentivirus-mediated RNAi knockdown of the gap junction protein, Cx43, attenuates the development of vascular restenosis following balloon injury.
Han XJ, Chen M, Hong T, Zhu LY, He D, Feng JG, Jiang LP
International journal of molecular medicine 2015 Apr;35(4):885-92
International journal of molecular medicine 2015 Apr;35(4):885-92
Long-distance communication between laryngeal carcinoma cells.
Antanavičiūtė I, Rysevaitė K, Liutkevičius V, Marandykina A, Rimkutė L, Sveikatienė R, Uloza V, Skeberdis VA
PloS one 2014;9(6):e99196
PloS one 2014;9(6):e99196
Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL).
Burkovetskaya M, Karpuk N, Xiong J, Bosch M, Boska MD, Takeuchi H, Suzumura A, Kielian T
PloS one 2014;9(4):e95023
PloS one 2014;9(4):e95023
Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus.
Kinjo ER, Higa GS, Morya E, Valle AC, Kihara AH, Britto LR
PloS one 2014;9(10):e109149
PloS one 2014;9(10):e109149
Does diabetes affect the distribution and number of interstitial cells and neuronal tissue in the ureter, bladder, prostate, and urethra of humans?
Canda AE, Dogan H, Kandemir O, Atmaca AF, Akbulut Z, Balbay MD
Central European journal of urology 2014;67(4):366-74
Central European journal of urology 2014;67(4):366-74
Connexins modulate autophagosome biogenesis.
Bejarano E, Yuste A, Patel B, Stout RF Jr, Spray DC, Cuervo AM
Nature cell biology 2014 May;16(5):401-14
Nature cell biology 2014 May;16(5):401-14
Reduced connexin 43 in eutopic endometrium and cultured endometrial stromal cells from subjects with endometriosis.
Yu J, Boicea A, Barrett KL, James CO, Bagchi IC, Bagchi MK, Nezhat C, Sidell N, Taylor RN
Molecular human reproduction 2014 Mar;20(3):260-70
Molecular human reproduction 2014 Mar;20(3):260-70
HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.
Zhang L, Chen X, Sharma P, Moon M, Sheftel AD, Dawood F, Nghiem MP, Wu J, Li RK, Gramolini AO, Sorensen PH, Penninger JM, Brumell JH, Liu PP
Nature communications 2014 Mar 11;5:3430
Nature communications 2014 Mar 11;5:3430
Mutation of human connexin43 amino acids s279/s282 increases protein stability upon treatment with epidermal growth factor.
Schmitt M, Leykauf K, Reinz E, Cheng H, Alonso A, Schenkel J
Cell biochemistry and biophysics 2014 Jun;69(2):379-84
Cell biochemistry and biophysics 2014 Jun;69(2):379-84
Rapid manifestation of reactive astrogliosis in acute hippocampal brain slices.
Takano T, He W, Han X, Wang F, Xu Q, Wang X, Oberheim Bush NA, Cruz N, Dienel GA, Nedergaard M
Glia 2014 Jan;62(1):78-95
Glia 2014 Jan;62(1):78-95
Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels.
León-Paravic CG, Figueroa VA, Guzmán DJ, Valderrama CF, Vallejos AA, Fiori MC, Altenberg GA, Reuss L, Retamal MA
The Journal of biological chemistry 2014 Dec 26;289(52):36150-7
The Journal of biological chemistry 2014 Dec 26;289(52):36150-7
Implanted neural progenitor cells regulate glial reaction to brain injury and establish gap junctions with host glial cells.
Talaverón R, Matarredona ER, de la Cruz RR, Macías D, Gálvez V, Pastor AM
Glia 2014 Apr;62(4):623-38
Glia 2014 Apr;62(4):623-38
Connexin 30 sets synaptic strength by controlling astroglial synapse invasion.
Pannasch U, Freche D, Dallérac G, Ghézali G, Escartin C, Ezan P, Cohen-Salmon M, Benchenane K, Abudara V, Dufour A, Lübke JH, Déglon N, Knott G, Holcman D, Rouach N
Nature neuroscience 2014 Apr;17(4):549-58
Nature neuroscience 2014 Apr;17(4):549-58
Both PKA and Epac pathways mediate N-acetylcysteine-induced Connexin43 preservation in rats with myocardial infarction.
Lee TM, Lin SZ, Chang NC
PloS one 2013;8(8):e71878
PloS one 2013;8(8):e71878
Tanshinone IIA increases the bystander effect of herpes simplex virus thymidine kinase/ganciclovir gene therapy via enhanced gap junctional intercellular communication.
Xiao J, Zhang G, Qiu P, Liu X, Wu Y, Du B, Li J, Zhou J, Li J, Tan Y
PloS one 2013;8(7):e67662
PloS one 2013;8(7):e67662
Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature.
Mayes DA, Rizvi TA, Titus-Mitchell H, Oberst R, Ciraolo GM, Vorhees CV, Robinson AP, Miller SD, Cancelas JA, Stemmer-Rachamimov AO, Ratner N
Cell reports 2013 Sep 26;4(6):1197-212
Cell reports 2013 Sep 26;4(6):1197-212
Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype.
Ivashchenko CY, Pipes GC, Lozinskaya IM, Lin Z, Xiaoping X, Needle S, Grygielko ET, Hu E, Toomey JR, Lepore JJ, Willette RN
American journal of physiology. Heart and circulatory physiology 2013 Sep 15;305(6):H913-22
American journal of physiology. Heart and circulatory physiology 2013 Sep 15;305(6):H913-22
Epigallocatechin-3-gallate-mediated cardioprotection by Akt/GSK-3β/caveolin signalling in H9c2 rat cardiomyoblasts.
Hsieh SR, Hsu CS, Lu CH, Chen WC, Chiu CH, Liou YM
Journal of biomedical science 2013 Nov 19;20(1):86
Journal of biomedical science 2013 Nov 19;20(1):86
Connexin-43 hemichannels contribute to the propagation of μ-calpain-mediated neuronal death in a cortical ablation injury model.
Ishii Y, Shintani-Ishida K, Yoshida K
Biochemical and biophysical research communications 2013 Nov 15;441(2):457-62
Biochemical and biophysical research communications 2013 Nov 15;441(2):457-62
Absence of venous valves in mice lacking Connexin37.
Munger SJ, Kanady JD, Simon AM
Developmental biology 2013 Jan 15;373(2):338-48
Developmental biology 2013 Jan 15;373(2):338-48
Striatal allografts in patients with Huntington's disease: impact of diminished astrocytes and vascularization on graft viability.
Cisbani G, Freeman TB, Soulet D, Saint-Pierre M, Gagnon D, Parent M, Hauser RA, Barker RA, Cicchetti F
Brain : a journal of neurology 2013 Feb;136(Pt 2):433-43
Brain : a journal of neurology 2013 Feb;136(Pt 2):433-43
Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signaling.
Mureli S, Gans CP, Bare DJ, Geenen DL, Kumar NM, Banach K
American journal of physiology. Heart and circulatory physiology 2013 Feb 15;304(4):H600-9
American journal of physiology. Heart and circulatory physiology 2013 Feb 15;304(4):H600-9
Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy.
Benz PM, Merkel CJ, Offner K, Abeßer M, Ullrich M, Fischer T, Bayer B, Wagner H, Gambaryan S, Ursitti JA, Adham IM, Linke WA, Feller SM, Fleming I, Renné T, Frantz S, Unger A, Schuh K
Cell communication and signaling : CCS 2013 Aug 12;11:56
Cell communication and signaling : CCS 2013 Aug 12;11:56
Blocking of connexin-mediated communication promotes neuroprotection during acute degeneration induced by mechanical trauma.
Paschon V, Higa GS, Resende RR, Britto LR, Kihara AH
PloS one 2012;7(9):e45449
PloS one 2012;7(9):e45449
Connexin and AMPA receptor expression changes over time in the rat olfactory bulb.
Corthell JT, Fadool DA, Trombley PQ
Neuroscience 2012 Oct 11;222:38-48
Neuroscience 2012 Oct 11;222:38-48
Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.
Liu X, Sun L, Torii M, Rakic P
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):8280-5
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):8280-5
Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells.
Asumda FZ, Chase PB
Differentiation; research in biological diversity 2012 Mar;83(3):106-15
Differentiation; research in biological diversity 2012 Mar;83(3):106-15
Prostaglandin-induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins.
Ghulé VV, Gray C, Galimberti A, Anumba DO
Journal of translational medicine 2012 Mar 7;10:40
Journal of translational medicine 2012 Mar 7;10:40
Neuronal gap junction coupling is regulated by glutamate and plays critical role in cell death during neuronal injury.
Wang Y, Song JH, Denisova JV, Park WM, Fontes JD, Belousov AB
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jan 11;32(2):713-25
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jan 11;32(2):713-25
Cardiac effects of osteostatin in mice.
Meyer R, Schreckenberg R, Kraus D, Kretschmer F, Schulz R, Schlüter KD
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2012 Feb;63(1):17-22
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2012 Feb;63(1):17-22
Reduced connexin43 expression correlates with c-Src activation, proliferation, and glucose uptake in reactive astrocytes after an excitotoxic insult.
Gangoso E, Ezan P, Valle-Casuso JC, Herrero-González S, Koulakoff A, Medina JM, Giaume C, Tabernero A
Glia 2012 Dec;60(12):2040-9
Glia 2012 Dec;60(12):2040-9
K ATP channel agonists preserve connexin43 protein in infarcted rats by a protein kinase C-dependent pathway.
Lee TM, Lin CC, Lien HY, Chen CC
Journal of cellular and molecular medicine 2012 Apr;16(4):776-88
Journal of cellular and molecular medicine 2012 Apr;16(4):776-88
Age-related changes in rat bone-marrow mesenchymal stem cell plasticity.
Asumda FZ, Chase PB
BMC cell biology 2011 Oct 12;12:44
BMC cell biology 2011 Oct 12;12:44
Gap junctions and hydrogen peroxide are involved in endothelium-derived hyperpolarising responses to bradykinin in omental arteries and veins isolated from pregnant women.
Hammond S, Mathewson AM, Baker PN, Mayhew TM, Dunn WR
European journal of pharmacology 2011 Oct 1;668(1-2):225-32
European journal of pharmacology 2011 Oct 1;668(1-2):225-32
Residual Cx45 and its relationship to Cx43 in murine ventricular myocardium.
Bao M, Kanter EM, Huang RY, Maxeiner S, Frank M, Zhang Y, Schuessler RB, Smith TW, Townsend RR, Rohrs HW, Berthoud VM, Willecke K, Laing JG, Yamada KA
Channels (Austin, Tex.) 2011 Nov-Dec;5(6):489-99
Channels (Austin, Tex.) 2011 Nov-Dec;5(6):489-99
Epidermal differentiation and loss of clonal growth potential of human limbal basal epithelial progenitor cells during intrastromal invasion.
Tan EK, He H, Tseng SC
Investigative ophthalmology & visual science 2011 Jun 28;52(7):4534-45
Investigative ophthalmology & visual science 2011 Jun 28;52(7):4534-45
Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity.
Karpuk N, Burkovetskaya M, Fritz T, Angle A, Kielian T
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jan 12;31(2):414-25
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jan 12;31(2):414-25
Reduced gap junctional communication among astrocytes in experimental diabetes: contributions of altered connexin protein levels and oxidative-nitrosative modifications.
Ball KK, Harik L, Gandhi GK, Cruz NF, Dienel GA
Journal of neuroscience research 2011 Dec;89(12):2052-67
Journal of neuroscience research 2011 Dec;89(12):2052-67
Ablation of connexin30 in transgenic mice alters expression patterns of connexin26 and connexin32 in glial cells and leptomeninges.
Lynn BD, Tress O, May D, Willecke K, Nagy JI
The European journal of neuroscience 2011 Dec;34(11):1783-93
The European journal of neuroscience 2011 Dec;34(11):1783-93
Focal adhesion kinase modulates radial glia-dependent neuronal migration through connexin-26.
Valiente M, Ciceri G, Rico B, Marín O
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 10;31(32):11678-91
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 10;31(32):11678-91
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
Yamaji S, Droggiti A, Lu SC, Martinez-Chantar ML, Warner A, Varela-Rey M
European journal of cell biology 2011 Apr;90(4):312-22
European journal of cell biology 2011 Apr;90(4):312-22
Interplay of chemical neurotransmitters regulates developmental increase in electrical synapses.
Park WM, Wang Y, Park S, Denisova JV, Fontes JD, Belousov AB
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Apr 20;31(16):5909-20
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Apr 20;31(16):5909-20
Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion.
Mersmann J, Koch A, Tran N, Zimmermann R, Granja TF, Larmann J, Herzog C, Theilmeier G, Bornstein SR, Kirschning CJ, Zacharowski K
Critical care medicine 2010 Oct;38(10):1927-32
Critical care medicine 2010 Oct;38(10):1927-32
Restraint stress induces connexin-43 translocation via α-adrenoceptors in rat heart.
Unuma K, Shintani-Ishida K, Yahagi N, Tsushima K, Shimosawa T, Ueyama T, Yoshida K
Circulation journal : official journal of the Japanese Circulation Society 2010 Nov;74(12):2693-701
Circulation journal : official journal of the Japanese Circulation Society 2010 Nov;74(12):2693-701
Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development.
Willems A, Batlouni SR, Esnal A, Swinnen JV, Saunders PT, Sharpe RM, França LR, De Gendt K, Verhoeven G
PloS one 2010 Nov 30;5(11):e14168
PloS one 2010 Nov 30;5(11):e14168
Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice.
Mei X, Ezan P, Giaume C, Koulakoff A
Neuroscience 2010 Nov 24;171(1):92-105
Neuroscience 2010 Nov 24;171(1):92-105
Hyperglycaemia and diabetes impair gap junctional communication among astrocytes.
Gandhi GK, Ball KK, Cruz NF, Dienel GA
ASN neuro 2010 Mar 15;2(2):e00030
ASN neuro 2010 Mar 15;2(2):e00030
17beta-Estradiol decreases vulnerability to ventricular arrhythmias by preserving connexin43 protein in infarcted rats.
Chen CC, Lin CC, Lee TM
European journal of pharmacology 2010 Mar 10;629(1-3):73-81
European journal of pharmacology 2010 Mar 10;629(1-3):73-81
Reorganization of gap junctions after focused ultrasound blood-brain barrier opening in the rat brain.
Alonso A, Reinz E, Jenne JW, Fatar M, Schmidt-Glenewinkel H, Hennerici MG, Meairs S
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010 Jul;30(7):1394-402
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010 Jul;30(7):1394-402
Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment.
Haass NK, Ripperger D, Wladykowski E, Dawson P, Gimotty PA, Blome C, Fischer F, Schmage P, Moll I, Brandner JM
Histochemistry and cell biology 2010 Jan;133(1):113-24
Histochemistry and cell biology 2010 Jan;133(1):113-24
Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.
del Castillo FJ, Cohen-Salmon M, Charollais A, Caille D, Lampe PD, Chavrier P, Meda P, Petit C
Human molecular genetics 2010 Jan 15;19(2):262-75
Human molecular genetics 2010 Jan 15;19(2):262-75
Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43.
Chen CC, Lien HY, Hsu YJ, Lin CC, Shih CM, Lee TM
Journal of applied physiology (Bethesda, Md. : 1985) 2010 Aug;109(2):541-52
Journal of applied physiology (Bethesda, Md. : 1985) 2010 Aug;109(2):541-52
Cyclic stretch downregulates arterial vascular connexin43 protein expression: an ex vivo study.
He Y, Shroff SG
Biomechanics and modeling in mechanobiology 2010 Apr;9(2):203-11
Biomechanics and modeling in mechanobiology 2010 Apr;9(2):203-11
Olfactory ensheathing cell membrane properties are shaped by connectivity.
Rela L, Bordey A, Greer CA
Glia 2010 Apr 15;58(6):665-78
Glia 2010 Apr 15;58(6):665-78
Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection.
Rodríguez-Sinovas A, Sánchez JA, González-Loyola A, Barba I, Morente M, Aguilar R, Agulló E, Miró-Casas E, Esquerda N, Ruiz-Meana M, García-Dorado D
The Journal of physiology 2010 Apr 1;588(Pt 7):1139-51
The Journal of physiology 2010 Apr 1;588(Pt 7):1139-51
Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues.
Bian W, Liau B, Badie N, Bursac N
Nature protocols 2009;4(10):1522-34
Nature protocols 2009;4(10):1522-34
Ischemia enhances translocation of connexin43 and gap junction intercellular communication, thereby propagating contraction band necrosis after reperfusion.
Shintani-Ishida K, Unuma K, Yoshida K
Circulation journal : official journal of the Japanese Circulation Society 2009 Sep;73(9):1661-8
Circulation journal : official journal of the Japanese Circulation Society 2009 Sep;73(9):1661-8
Ischemia enhances translocation of connexin43 and gap junction intercellular communication, thereby propagating contraction band necrosis after reperfusion.
Shintani-Ishida K, Unuma K, Yoshida K
Circulation journal : official journal of the Japanese Circulation Society 2009 Sep;73(9):1661-8
Circulation journal : official journal of the Japanese Circulation Society 2009 Sep;73(9):1661-8
Expression of connexins in normal and neoplastic canine bone tissue.
Sanches DS, Pires CG, Fukumasu H, Cogliati B, Matsuzaki P, Chaible LM, Torres LN, Ferrigno CR, Dagli ML
Veterinary pathology 2009 Sep;46(5):846-59
Veterinary pathology 2009 Sep;46(5):846-59
Replacement of connexin 43 by connexin 32 in a knock-in mice model attenuates aortic endothelium-derived hyperpolarizing factor-mediated relaxation.
López D, Rodríguez-Sinovas A, Agulló E, García A, Sánchez JA, García-Dorado D
Experimental physiology 2009 Oct;94(10):1088-97
Experimental physiology 2009 Oct;94(10):1088-97
Myocardin is required for cardiomyocyte survival and maintenance of heart function.
Huang J, Min Lu M, Cheng L, Yuan LJ, Zhu X, Stout AL, Chen M, Li J, Parmacek MS
Proceedings of the National Academy of Sciences of the United States of America 2009 Nov 3;106(44):18734-9
Proceedings of the National Academy of Sciences of the United States of America 2009 Nov 3;106(44):18734-9
Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality.
Wang HX, Tong D, El-Gehani F, Tekpetey FR, Kidder GM
Journal of cellular and molecular medicine 2009 May;13(5):972-84
Journal of cellular and molecular medicine 2009 May;13(5):972-84
Evidence against a role of gap junctions in vestibular compensation.
Beraneck M, Uno A, Vassias I, Idoux E, De Waele C, Vidal PP, Vibert N
Neuroscience letters 2009 Jan 30;450(2):97-101
Neuroscience letters 2009 Jan 30;450(2):97-101
Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.
Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P
Human molecular genetics 2009 Feb 1;18(3):428-39
Human molecular genetics 2009 Feb 1;18(3):428-39
Tyrosine-dependent basolateral targeting of human connexin43-eYFP in Madin-Darby canine kidney cells can be disrupted by the oculodentodigital dysplasia mutation L90V.
Chtchetinin J, Gifford WD, Li S, Paznekas WA, Jabs EW, Lai A
The FEBS journal 2009 Dec;276(23):6992-7005
The FEBS journal 2009 Dec;276(23):6992-7005
Eps15 interacts with ubiquitinated Cx43 and mediates its internalization.
Girão H, Catarino S, Pereira P
Experimental cell research 2009 Dec 10;315(20):3587-97
Experimental cell research 2009 Dec 10;315(20):3587-97
Unique expression of connexins in the human cochlea.
Liu W, Boström M, Kinnefors A, Rask-Andersen H
Hearing research 2009 Apr;250(1-2):55-62
Hearing research 2009 Apr;250(1-2):55-62
Cx43 contributes to TGF-beta signaling to regulate differentiation of cardiac fibroblasts into myofibroblasts.
Asazuma-Nakamura Y, Dai P, Harada Y, Jiang Y, Hamaoka K, Takamatsu T
Experimental cell research 2009 Apr 15;315(7):1190-9
Experimental cell research 2009 Apr 15;315(7):1190-9
Taurine suppresses the spread of cell death in electrically coupled RPE cells.
Udawatte C, Qian H, Mangini NJ, Kennedy BG, Ripps H
Molecular vision 2008;14:1940-50
Molecular vision 2008;14:1940-50
Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes.
Koulakoff A, Ezan P, Giaume C
Glia 2008 Sep;56(12):1299-311
Glia 2008 Sep;56(12):1299-311
Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1.
Li X, Kamasawa N, Ciolofan C, Olson CO, Lu S, Davidson KG, Yasumura T, Shigemoto R, Rash JE, Nagy JI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Sep 24;28(39):9769-89
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Sep 24;28(39):9769-89
Differential expression of connexins during histogenesis of the chick retina.
Kihara AH, Paschon V, Akamine PS, Saito KC, Leonelli M, Jiang JX, Hamassaki DE, Britto LR
Developmental neurobiology 2008 Sep 15;68(11):1287-302
Developmental neurobiology 2008 Sep 15;68(11):1287-302
Novel mutations in GJA1 cause oculodentodigital syndrome.
Fenwick A, Richardson RJ, Butterworth J, Barron MJ, Dixon MJ
Journal of dental research 2008 Nov;87(11):1021-6
Journal of dental research 2008 Nov;87(11):1021-6
Effects of 18-glycyrrhetinic acid on serine 368 phosphorylation of connexin43 in rat neonatal cardiomyocytes.
Liang JY, Wang SM, Chung TH, Yang SH, Wu JC
Cell biology international 2008 Nov;32(11):1371-9
Cell biology international 2008 Nov;32(11):1371-9
No impact of protein phosphatases on connexin 43 phosphorylation in ischemic preconditioning.
Totzeck A, Boengler K, van de Sand A, Konietzka I, Gres P, Garcia-Dorado D, Heusch G, Schulz R
American journal of physiology. Heart and circulatory physiology 2008 Nov;295(5):H2106-12
American journal of physiology. Heart and circulatory physiology 2008 Nov;295(5):H2106-12
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.
Li J, Levin MD, Xiong Y, Petrenko N, Patel VV, Radice GL
Journal of molecular and cellular cardiology 2008 Mar;44(3):597-606
Journal of molecular and cellular cardiology 2008 Mar;44(3):597-606
Altered expression of connexin43 contributes to the arrhythmogenic substrate during the development of heart failure in cardiomyopathic hamster.
Sato T, Ohkusa T, Honjo H, Suzuki S, Yoshida MA, Ishiguro YS, Nakagawa H, Yamazaki M, Yano M, Kodama I, Matsuzaki M
American journal of physiology. Heart and circulatory physiology 2008 Mar;294(3):H1164-73
American journal of physiology. Heart and circulatory physiology 2008 Mar;294(3):H1164-73
Expression of matrix metalloproteinases, cytokines, and connexins in diabetic and nondiabetic human keratinocytes before and after transplantation into an ex vivo wound-healing model.
Brandner JM, Zacheja S, Houdek P, Moll I, Lobmann R
Diabetes care 2008 Jan;31(1):114-20
Diabetes care 2008 Jan;31(1):114-20
Gap junctional intercellular communication is required to maintain embryonic stem cells in a non-differentiated and proliferative state.
Todorova MG, Soria B, Quesada I
Journal of cellular physiology 2008 Feb;214(2):354-62
Journal of cellular physiology 2008 Feb;214(2):354-62
Impact of ultraviolet radiation on the expression of marker proteins of gap and adhesion junctions in human epidermis.
Gambichler T, Rotterdam S, Tigges C, Altmeyer P, Bechara FG
Photodermatology, photoimmunology & photomedicine 2008 Dec;24(6):318-21
Photodermatology, photoimmunology & photomedicine 2008 Dec;24(6):318-21
Limited intravascular coupling in the rodent brainstem and retina supports a role for glia in regional blood flow.
Kuo IY, Chan-Ling T, Wojcikiewicz RJ, Hill CE
The Journal of comparative neurology 2008 Dec 20;511(6):773-87
The Journal of comparative neurology 2008 Dec 20;511(6):773-87
Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival.
Laws MJ, Taylor RN, Sidell N, DeMayo FJ, Lydon JP, Gutstein DE, Bagchi MK, Bagchi IC
Development (Cambridge, England) 2008 Aug;135(15):2659-68
Development (Cambridge, England) 2008 Aug;135(15):2659-68
Immunoreactivity for the GABAA receptor alpha1 subunit, somatostatin and Connexin36 distinguishes axoaxonic, basket, and bistratified interneurons of the rat hippocampus.
Baude A, Bleasdale C, Dalezios Y, Somogyi P, Klausberger T
Cerebral cortex (New York, N.Y. : 1991) 2007 Sep;17(9):2094-107
Cerebral cortex (New York, N.Y. : 1991) 2007 Sep;17(9):2094-107
Repeated simulated ischemia and protection against gap junctional uncoupling.
Sundset R, Ytrehus K, Zhang Y, Saffitz JE, Yamada KA
Cell communication & adhesion 2007 Sep-Oct;14(5):239-49
Cell communication & adhesion 2007 Sep-Oct;14(5):239-49
Connexin40 regulates renin production and blood pressure.
Krattinger N, Capponi A, Mazzolai L, Aubert JF, Caille D, Nicod P, Waeber G, Meda P, Haefliger JA
Kidney international 2007 Oct;72(7):814-22
Kidney international 2007 Oct;72(7):814-22
The in vitro behaviour and patterns of colony formation of murine epithelial stem cells.
Tudor D, Chaudry F, Harper L, Mackenzie IC
Cell proliferation 2007 Oct;40(5):706-20
Cell proliferation 2007 Oct;40(5):706-20
Biphasic regulation of AP-1 subunits during human epidermal wound healing.
Neub A, Houdek P, Ohnemus U, Moll I, Brandner JM
The Journal of investigative dermatology 2007 Oct;127(10):2453-62
The Journal of investigative dermatology 2007 Oct;127(10):2453-62
The proteasome regulates the interaction between Cx43 and ZO-1.
Girao H, Pereira P
Journal of cellular biochemistry 2007 Oct 15;102(3):719-28
Journal of cellular biochemistry 2007 Oct 15;102(3):719-28
Downregulation of connexin40 and increased prevalence of atrial arrhythmias in transgenic mice with cardiac-restricted overexpression of tumor necrosis factor.
Sawaya SE, Rajawat YS, Rami TG, Szalai G, Price RL, Sivasubramanian N, Mann DL, Khoury DS
American journal of physiology. Heart and circulatory physiology 2007 Mar;292(3):H1561-7
American journal of physiology. Heart and circulatory physiology 2007 Mar;292(3):H1561-7
Changes in phosphorylation of connexin43 in rats during acute myocardial hypoxia and effects of antiarrhythmic peptide on the phosphorylation.
Wang R, Zhang C, Ruan Y, Liu N, Wang L
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2007 Jun;27(3):241-4
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2007 Jun;27(3):241-4
Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus.
Rash JE, Olson CO, Davidson KG, Yasumura T, Kamasawa N, Nagy JI
Neuroscience 2007 Jul 29;147(4):938-56
Neuroscience 2007 Jul 29;147(4):938-56
Gap junctional intercellular communication capacity by gap-FRAP technique: a comparative study.
Abbaci M, Barberi-Heyob M, Stines JR, Blondel W, Dumas D, Guillemin F, Didelon J
Biotechnology journal 2007 Jan;2(1):50-61
Biotechnology journal 2007 Jan;2(1):50-61
Temporal profile of connexin 43 expression after photothrombotic lesion in rat brain.
Haupt C, Witte OW, Frahm C
Neuroscience 2007 Jan 19;144(2):562-70
Neuroscience 2007 Jan 19;144(2):562-70
Modulation of connexin expression and gap junction communication in astrocytes by the gram-positive bacterium S. aureus.
Esen N, Shuffield D, Syed MM, Kielian T
Glia 2007 Jan 1;55(1):104-17
Glia 2007 Jan 1;55(1):104-17
18beta-glycyrrhetinic acid promotes src interaction with connexin43 in rat cardiomyocytes.
Chung TH, Wang SM, Chang YC, Chen YL, Wu JC
Journal of cellular biochemistry 2007 Feb 15;100(3):653-64
Journal of cellular biochemistry 2007 Feb 15;100(3):653-64
Aconitine alters connexin43 phosphorylation status and [Ca2+] oscillation patterns in cultured ventricular myocytes of neonatal rats.
Zhang SW, Liu Y, Huang GZ, Liu L
Toxicology in vitro : an international journal published in association with BIBRA 2007 Dec;21(8):1476-85
Toxicology in vitro : an international journal published in association with BIBRA 2007 Dec;21(8):1476-85
Gap junction adhesion is necessary for radial migration in the neocortex.
Elias LA, Wang DD, Kriegstein AR
Nature 2007 Aug 23;448(7156):901-7
Nature 2007 Aug 23;448(7156):901-7
Pressure induces loss of gap junction communication and redistribution of connexin 43 in astrocytes.
Malone P, Miao H, Parker A, Juarez S, Hernandez MR
Glia 2007 Aug 1;55(10):1085-98
Glia 2007 Aug 1;55(10):1085-98
Dual regulation of astrocyte gap junction hemichannels by growth factors and a pro-inflammatory cytokine via the mitogen-activated protein kinase cascade.
Morita M, Saruta C, Kozuka N, Okubo Y, Itakura M, Takahashi M, Kudo Y
Glia 2007 Apr 1;55(5):508-15
Glia 2007 Apr 1;55(5):508-15
Ubiquitin protein ligase Nedd4 binds to connexin43 by a phosphorylation-modulated process.
Leykauf K, Salek M, Bomke J, Frech M, Lehmann WD, Dürst M, Alonso A
Journal of cell science 2006 Sep 1;119(Pt 17):3634-42
Journal of cell science 2006 Sep 1;119(Pt 17):3634-42
Reduction and redistribution of gap and adherens junction proteins after ischemia and reperfusion.
Tansey EE, Kwaku KF, Hammer PE, Cowan DB, Federman M, Levitsky S, McCully JD
The Annals of thoracic surgery 2006 Oct;82(4):1472-9
The Annals of thoracic surgery 2006 Oct;82(4):1472-9
Expression of connexins 36, 43, and 45 during postnatal development of the mouse retina.
Kihara AH, Mantovani de Castro L, Belmonte MA, Yan CY, Moriscot AS, Hamassaki DE
Journal of neurobiology 2006 Nov;66(13):1397-410
Journal of neurobiology 2006 Nov;66(13):1397-410
Spatial separation of endothelial small- and intermediate-conductance calcium-activated potassium channels (K(Ca)) and connexins: possible relationship to vasodilator function?
Sandow SL, Neylon CB, Chen MX, Garland CJ
Journal of anatomy 2006 Nov;209(5):689-98
Journal of anatomy 2006 Nov;209(5):689-98
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue.
Cluff AH, Byström B, Klimaviciute A, Dahlqvist C, Cebers G, Malmström A, Ekman-Ordeberg G
Reproductive biology and endocrinology : RB&E 2006 May 4;4:24
Reproductive biology and endocrinology : RB&E 2006 May 4;4:24
Prolonged dark adaptation changes connexin expression in the mouse retina.
Kihara AH, de Castro LM, Moriscot AS, Hamassaki DE
Journal of neuroscience research 2006 May 15;83(7):1331-41
Journal of neuroscience research 2006 May 15;83(7):1331-41
GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function.
Membrez M, Hummler E, Beermann F, Haefliger JA, Savioz R, Pedrazzini T, Thorens B
Molecular and cellular biology 2006 Jun;26(11):4268-76
Molecular and cellular biology 2006 Jun;26(11):4268-76
Altered expression of connexin subtypes in mesial temporal lobe epilepsy in humans.
Collignon F, Wetjen NM, Cohen-Gadol AA, Cascino GD, Parisi J, Meyer FB, Marsh WR, Roche P, Weigand SD
Journal of neurosurgery 2006 Jul;105(1):77-87
Journal of neurosurgery 2006 Jul;105(1):77-87
Overexpression of cardiac connexin45 increases susceptibility to ventricular tachyarrhythmias in vivo.
Betsuyaku T, Nnebe NS, Sundset R, Patibandla S, Krueger CM, Yamada KA
American journal of physiology. Heart and circulatory physiology 2006 Jan;290(1):H163-71
American journal of physiology. Heart and circulatory physiology 2006 Jan;290(1):H163-71
Cardiac cells implanted within the outer aortic wall of rats generate measurable contractile force.
Dai W, Hale SL, Kloner RA
Regenerative medicine 2006 Jan;1(1):119-24
Regenerative medicine 2006 Jan;1(1):119-24
Gap junctional coupling and connexin immunoreactivity in rabbit retinal glia.
Zahs KR, Ceelen PW
Visual neuroscience 2006 Jan-Feb;23(1):1-10
Visual neuroscience 2006 Jan-Feb;23(1):1-10
G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis.
Kuhlmann MT, Kirchhof P, Klocke R, Hasib L, Stypmann J, Fabritz L, Stelljes M, Tian W, Zwiener M, Mueller M, Kienast J, Breithardt G, Nikol S
The Journal of experimental medicine 2006 Jan 23;203(1):87-97
The Journal of experimental medicine 2006 Jan 23;203(1):87-97
Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis.
Haass NK, Wladykowski E, Kief S, Moll I, Brandner JM
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006 Feb;54(2):171-82
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006 Feb;54(2):171-82
Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation.
Kubota T, Sato K, Arishima H, Takeuchi H, Kitai R, Nakagawa T
Neuropathology : official journal of the Japanese Society of Neuropathology 2006 Feb;26(1):72-81
Neuropathology : official journal of the Japanese Society of Neuropathology 2006 Feb;26(1):72-81
Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation.
Kubota T, Sato K, Arishima H, Takeuchi H, Kitai R, Nakagawa T
Neuropathology : official journal of the Japanese Society of Neuropathology 2006 Feb;26(1):72-81
Neuropathology : official journal of the Japanese Society of Neuropathology 2006 Feb;26(1):72-81
The TLR3 ligand polyI: C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the NF-kappaB and PI3 kinase pathways.
Zhao Y, Rivieccio MA, Lutz S, Scemes E, Brosnan CF
Glia 2006 Dec;54(8):775-85
Glia 2006 Dec;54(8):775-85
Redistribution of connexin43 in regional acute ischemic myocardium: influence of ischemic preconditioning.
Vetterlein F, Mühlfeld C, Cetegen C, Volkmann R, Schrader C, Hellige G
American journal of physiology. Heart and circulatory physiology 2006 Aug;291(2):H813-9
American journal of physiology. Heart and circulatory physiology 2006 Aug;291(2):H813-9
Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin.
Gavillet B, Rougier JS, Domenighetti AA, Behar R, Boixel C, Ruchat P, Lehr HA, Pedrazzini T, Abriel H
Circulation research 2006 Aug 18;99(4):407-14
Circulation research 2006 Aug 18;99(4):407-14
Phosphorylation of the gap junction protein Connexin43 in CIN III lesions and cervical carcinomas.
Steinhoff I, Leykauf K, Bleyl U, Dürst M, Alonso A
Cancer letters 2006 Apr 28;235(2):291-7
Cancer letters 2006 Apr 28;235(2):291-7
Connexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning.
Kamasawa N, Sik A, Morita M, Yasumura T, Davidson KG, Nagy JI, Rash JE
Neuroscience 2005;136(1):65-86
Neuroscience 2005;136(1):65-86
Expression of connexins 26 and 43 in canine hyperplastic and neoplastic mammary glands.
Torres LN, Matera JM, Vasconcellos CH, Avanzo JL, Hernandez-Blazquez FJ, Dagli ML
Veterinary pathology 2005 Sep;42(5):633-41
Veterinary pathology 2005 Sep;42(5):633-41
Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb.
Rash JE, Davidson KG, Kamasawa N, Yasumura T, Kamasawa M, Zhang C, Michaels R, Restrepo D, Ottersen OP, Olson CO, Nagy JI
Journal of neurocytology 2005 Sep;34(3-5):307-41
Journal of neurocytology 2005 Sep;34(3-5):307-41
Drebrin, an actin-binding, cell-type characteristic protein: induction and localization in epithelial skin tumors and cultured keratinocytes.
Peitsch WK, Hofmann I, Bulkescher J, Hergt M, Spring H, Bleyl U, Goerdt S, Franke WW
The Journal of investigative dermatology 2005 Oct;125(4):761-74
The Journal of investigative dermatology 2005 Oct;125(4):761-74
Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions.
Valiunas V, Polosina YY, Miller H, Potapova IA, Valiuniene L, Doronin S, Mathias RT, Robinson RB, Rosen MR, Cohen IS, Brink PR
The Journal of physiology 2005 Oct 15;568(Pt 2):459-68
The Journal of physiology 2005 Oct 15;568(Pt 2):459-68
The phosphorylated form of connexin43 is up-regulated in breast hyperplasias and carcinomas and in their neoformed capillaries.
Gould VE, Mosquera JM, Leykauf K, Gattuso P, Dürst M, Alonso A
Human pathology 2005 May;36(5):536-45
Human pathology 2005 May;36(5):536-45
Augmentation of differentiation and gap junction function by kaempferol in partially differentiated colon cancer cells.
Nakamura Y, Chang CC, Mori T, Sato K, Ohtsuki K, Upham BL, Trosko JE
Carcinogenesis 2005 Mar;26(3):665-71
Carcinogenesis 2005 Mar;26(3):665-71
Matrix-protein-specific regulation of Cx43 expression in cardiac myocytes subjected to mechanical load.
Shanker AJ, Yamada K, Green KG, Yamada KA, Saffitz JE
Circulation research 2005 Mar 18;96(5):558-66
Circulation research 2005 Mar 18;96(5):558-66
Epithelial-mesenchymal transition in colonies of rhesus monkey embryonic stem cells: a model for processes involved in gastrulation.
Behr R, Heneweer C, Viebahn C, Denker HW, Thie M
Stem cells (Dayton, Ohio) 2005 Jun-Jul;23(6):805-16
Stem cells (Dayton, Ohio) 2005 Jun-Jul;23(6):805-16
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
Penes MC, Li X, Nagy JI
The European journal of neuroscience 2005 Jul;22(2):404-18
The European journal of neuroscience 2005 Jul;22(2):404-18
Efferent vagal nerve stimulation protects heart against ischemia-induced arrhythmias by preserving connexin43 protein.
Ando M, Katare RG, Kakinuma Y, Zhang D, Yamasaki F, Muramoto K, Sato T
Circulation 2005 Jul 12;112(2):164-70
Circulation 2005 Jul 12;112(2):164-70
Functional organization of the bovine rumen epithelium.
Graham C, Simmons NL
American journal of physiology. Regulatory, integrative and comparative physiology 2005 Jan;288(1):R173-81
American journal of physiology. Regulatory, integrative and comparative physiology 2005 Jan;288(1):R173-81
Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion.
Hunter AW, Barker RJ, Zhu C, Gourdie RG
Molecular biology of the cell 2005 Dec;16(12):5686-98
Molecular biology of the cell 2005 Dec;16(12):5686-98
Postnatal development of GFAP, connexin43 and connexin30 in cat visual cortex.
Rochefort N, Quenech'du N, Ezan P, Giaume C, Milleret C
Brain research. Developmental brain research 2005 Dec 7;160(2):252-64
Brain research. Developmental brain research 2005 Dec 7;160(2):252-64
Distinct pathways regulate expression of cardiac electrical and mechanical junction proteins in response to stretch.
Yamada K, Green KG, Samarel AM, Saffitz JE
Circulation research 2005 Aug 19;97(4):346-53
Circulation research 2005 Aug 19;97(4):346-53
Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning.
Boengler K, Dodoni G, Rodriguez-Sinovas A, Cabestrero A, Ruiz-Meana M, Gres P, Konietzka I, Lopez-Iglesias C, Garcia-Dorado D, Di Lisa F, Heusch G, Schulz R
Cardiovascular research 2005 Aug 1;67(2):234-44
Cardiovascular research 2005 Aug 1;67(2):234-44
Differential expression and localisation of connexin-37 and connexin-43 in follicles of different stages in the 4-week-old mouse ovary.
Teilmann SC
Molecular and cellular endocrinology 2005 Apr 29;234(1-2):27-35
Molecular and cellular endocrinology 2005 Apr 29;234(1-2):27-35
Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation.
Abdelmohsen K, Patak P, Von Montfort C, Melchheier I, Sies H, Klotz LO
Methods in enzymology 2004;378:258-72
Methods in enzymology 2004;378:258-72
Connexin47, connexin29 and connexin32 co-expression in oligodendrocytes and Cx47 association with zonula occludens-1 (ZO-1) in mouse brain.
Li X, Ionescu AV, Lynn BD, Lu S, Kamasawa N, Morita M, Davidson KG, Yasumura T, Rash JE, Nagy JI
Neuroscience 2004;126(3):611-30
Neuroscience 2004;126(3):611-30
17beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor.
Chung TH, Wang SM, Wu JC
Journal of molecular and cellular cardiology 2004 Nov;37(5):1013-22
Journal of molecular and cellular cardiology 2004 Nov;37(5):1013-22
2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studies.
Paku S, Nagy P, Kopper L, Thorgeirsson SS
Hepatology (Baltimore, Md.) 2004 May;39(5):1353-61
Hepatology (Baltimore, Md.) 2004 May;39(5):1353-61
Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healing.
Brandner JM, Houdek P, Hüsing B, Kaiser C, Moll I
The Journal of investigative dermatology 2004 May;122(5):1310-20
The Journal of investigative dermatology 2004 May;122(5):1310-20
Regulation of purified and reconstituted connexin 43 hemichannels by protein kinase C-mediated phosphorylation of Serine 368.
Bao X, Reuss L, Altenberg GA
The Journal of biological chemistry 2004 May 7;279(19):20058-66
The Journal of biological chemistry 2004 May 7;279(19):20058-66
Four classes of intercellular channels between glial cells in the CNS.
Altevogt BM, Paul DL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 May 5;24(18):4313-23
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 May 5;24(18):4313-23
Ischemic preconditioning protects against gap junctional uncoupling in cardiac myofibroblasts.
Sundset R, Cooper M, Mikalsen SO, Ytrehus K
Cell communication & adhesion 2004 Mar-Aug;11(2-4):51-66
Cell communication & adhesion 2004 Mar-Aug;11(2-4):51-66
Ischemic preconditioning protects against gap junctional uncoupling in cardiac myofibroblasts.
Sundset R, Cooper M, Mikalsen SO, Ytrehus K
Cell communication & adhesion 2004 Mar-Aug;11(2-4):51-66
Cell communication & adhesion 2004 Mar-Aug;11(2-4):51-66
Effects of cellular cardiomyoplasty on ventricular remodeling assessed by Doppler echocardiography and topographic immunohistochemistry.
Yoshiyama M, Hayashi T, Nakamura Y, Omura T, Izumi Y, Matsumoto R, Takeuchi K, Kitaura Y, Yoshikawa J
Circulation journal : official journal of the Japanese Circulation Society 2004 Jun;68(6):580-6
Circulation journal : official journal of the Japanese Circulation Society 2004 Jun;68(6):580-6
Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model.
Janczewski AM, Zahid M, Lemster BH, Frye CS, Gibson G, Higuchi Y, Kranias EG, Feldman AM, McTiernan CF
Cardiovascular research 2004 Jun 1;62(3):468-80
Cardiovascular research 2004 Jun 1;62(3):468-80
Implantation of immature neonatal cardiac cells into the wall of the aorta in rats: a novel model for studying morphological and functional development of heart cells in an extracardiac environment.
Dai W, Hale SL, Kloner RA
Circulation 2004 Jul 20;110(3):324-9
Circulation 2004 Jul 20;110(3):324-9
Structural and molecular pathology of the heart in Carvajal syndrome.
Kaplan SR, Gard JJ, Carvajal-Huerta L, Ruiz-Cabezas JC, Thiene G, Saffitz JE
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2004 Jan-Feb;13(1):26-32
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2004 Jan-Feb;13(1):26-32
The vascular endothelial growth factor-induced disruption of gap junctions is relayed by an autocrine communication via ATP release in coronary capillary endothelium.
Thuringer D
Annals of the New York Academy of Sciences 2004 Dec;1030:14-27
Annals of the New York Academy of Sciences 2004 Dec;1030:14-27
Connexin29 and connexin32 at oligodendrocyte and astrocyte gap junctions and in myelin of the mouse central nervous system.
Nagy JI, Ionescu AV, Lynn BD, Rash JE
The Journal of comparative neurology 2003 Sep 22;464(3):356-70
The Journal of comparative neurology 2003 Sep 22;464(3):356-70
ECM-induced gap junctional communication enhances mammary epithelial cell differentiation.
El-Sabban ME, Sfeir AJ, Daher MH, Kalaany NY, Bassam RA, Talhouk RS
Journal of cell science 2003 Sep 1;116(Pt 17):3531-41
Journal of cell science 2003 Sep 1;116(Pt 17):3531-41
Signaling at the gliovascular interface.
Simard M, Arcuino G, Takano T, Liu QS, Nedergaard M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Oct 8;23(27):9254-62
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Oct 8;23(27):9254-62
Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases.
Abdelmohsen K, Gerber PA, von Montfort C, Sies H, Klotz LO
The Journal of biological chemistry 2003 Oct 3;278(40):38360-7
The Journal of biological chemistry 2003 Oct 3;278(40):38360-7
Role of catenins in the development of gap junctions in rat cardiomyocytes.
Wu JC, Tsai RY, Chung TH
Journal of cellular biochemistry 2003 Mar 1;88(4):823-35
Journal of cellular biochemistry 2003 Mar 1;88(4):823-35
Differential expression of connexin 43 in the chick tangential vestibular nucleus.
Popratiloff A, Pollack SM, Giaume C, Peusner KD
Journal of neuroscience research 2003 Mar 1;71(5):617-28
Journal of neuroscience research 2003 Mar 1;71(5):617-28
Phosphorylation and subcellular distribution of connexin43 in normal and stressed cells.
Leykauf K, Dürst M, Alonso A
Cell and tissue research 2003 Jan;311(1):23-30
Cell and tissue research 2003 Jan;311(1):23-30
Uterine leiomyomas express myometrial contractile-associated proteins involved in pregnancy-related hormone signaling.
Cesen-Cummings K, Houston KD, Copland JA, Moorman VJ, Walker CL, Davis BJ
Journal of the Society for Gynecologic Investigation 2003 Jan;10(1):11-20
Journal of the Society for Gynecologic Investigation 2003 Jan;10(1):11-20
Connexin immunoreactivity in glial cells of the rat retina.
Zahs KR, Kofuji P, Meier C, Dermietzel R
The Journal of comparative neurology 2003 Jan 20;455(4):531-46
The Journal of comparative neurology 2003 Jan 20;455(4):531-46
Coupling of astrocyte connexins Cx26, Cx30, Cx43 to oligodendrocyte Cx29, Cx32, Cx47: Implications from normal and connexin32 knockout mice.
Nagy JI, Ionescu AV, Lynn BD, Rash JE
Glia 2003 Dec;44(3):205-18
Glia 2003 Dec;44(3):205-18
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Luo Y, Radice GL
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Luo Y, Radice GL
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Regulation of gap junction protein (connexin) genes and function in differentiating ES cells.
Oyamada M, Oyamada Y, Kaneko T, Takamatsu T
Methods in molecular biology (Clifton, N.J.) 2002;185:63-9
Methods in molecular biology (Clifton, N.J.) 2002;185:63-9
Anticonvulsant actions of gap junctional blockers in an in vitro seizure model.
Jahromi SS, Wentlandt K, Piran S, Carlen PL
Journal of neurophysiology 2002 Oct;88(4):1893-902
Journal of neurophysiology 2002 Oct;88(4):1893-902
Anticonvulsant actions of gap junctional blockers in an in vitro seizure model.
Jahromi SS, Wentlandt K, Piran S, Carlen PL
Journal of neurophysiology 2002 Oct;88(4):1893-902
Journal of neurophysiology 2002 Oct;88(4):1893-902
Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions.
Barker RJ, Price RL, Gourdie RG
Circulation research 2002 Feb 22;90(3):317-24
Circulation research 2002 Feb 22;90(3):317-24
Microglia and astrocytes may participate in the shaping of visual callosal projections during postnatal development.
Rochefort N, Quenech'du N, Watroba L, Mallat M, Giaume C, Milleret C
Journal of physiology, Paris 2002 Apr-Jun;96(3-4):183-92
Journal of physiology, Paris 2002 Apr-Jun;96(3-4):183-92
Microglia and astrocytes may participate in the shaping of visual callosal projections during postnatal development.
Rochefort N, Quenech'du N, Watroba L, Mallat M, Giaume C, Milleret C
Journal of physiology, Paris 2002 Apr-Jun;96(3-4):183-92
Journal of physiology, Paris 2002 Apr-Jun;96(3-4):183-92
Expression of connexin43 in mouse Leydig, Sertoli, and germinal cells at different stages of postnatal development.
Bravo-Moreno JF, Díaz-Sánchez V, Montoya-Flores JG, Lamoyi E, Saéz JC, Pérez-Armendariz EM
The Anatomical record 2001 Sep 1;264(1):13-24
The Anatomical record 2001 Sep 1;264(1):13-24
Developmental regulation of connexin 43 expression in fetal mouse testicular cells.
Pérez-Armendariz EM, Lamoyi E, Mason JI, Cisneros-Armas D, Luu-The V, Bravo Moreno JF
The Anatomical record 2001 Nov 1;264(3):237-46
The Anatomical record 2001 Nov 1;264(3):237-46
Activation of fibres in rat sciatic nerve alters phosphorylation state of connexin-43 at astrocytic gap junctions in spinal cord: evidence for junction regulation by neuronal-glial interactions.
Li WE, Nagy JI
Neuroscience 2000;97(1):113-23
Neuroscience 2000;97(1):113-23
Activation of fibres in rat sciatic nerve alters phosphorylation state of connexin-43 at astrocytic gap junctions in spinal cord: evidence for junction regulation by neuronal-glial interactions.
Li WE, Nagy JI
Neuroscience 2000;97(1):113-23
Neuroscience 2000;97(1):113-23
The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction.
Nusrat A, Chen JA, Foley CS, Liang TW, Tom J, Cromwell M, Quan C, Mrsny RJ
The Journal of biological chemistry 2000 Sep 22;275(38):29816-22
The Journal of biological chemistry 2000 Sep 22;275(38):29816-22
Growth hormone increases connexin-43 expression in the cerebral cortex and hypothalamus.
Aberg ND, Carlsson B, Rosengren L, Oscarsson J, Isaksson OG, Rönnbäck L, Eriksson PS
Endocrinology 2000 Oct;141(10):3879-86
Endocrinology 2000 Oct;141(10):3879-86
Connexin43 phosphorylation state and intercellular communication in cultured astrocytes following hypoxia and protein phosphatase inhibition.
Li WE, Nagy JI
The European journal of neuroscience 2000 Jul;12(7):2644-50
The European journal of neuroscience 2000 Jul;12(7):2644-50
Connexin43 phosphorylation state and intercellular communication in cultured astrocytes following hypoxia and protein phosphatase inhibition.
Li WE, Nagy JI
The European journal of neuroscience 2000 Jul;12(7):2644-50
The European journal of neuroscience 2000 Jul;12(7):2644-50
Connexin 26 expression and extensive gap junctional coupling in cultures of GT1-7 cells secreting gonadotropin-releasing hormone.
Hu L, Olson AJ, Weiner RI, Goldsmith PC
Neuroendocrinology 1999 Oct;70(4):221-7
Neuroendocrinology 1999 Oct;70(4):221-7
Identification of gap junctional connexin-32 mRNA and protein in gonadotropin-releasing hormone neurons of the female rat.
Hosny S, Jennes L
Neuroendocrinology 1998 Feb;67(2):101-8
Neuroendocrinology 1998 Feb;67(2):101-8
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- Figure 1 Tan IIA treatment of B16 cells results in the upregulation of Cx26 and Cx43 proteins. B16 cells were treated with Tan IIA (0, 5, 10 or 20 uM) for 72 h. (A) Immunoblotting was performed using antibody against Cx26, Cx30 and Cx43. Actin was also tested as a loading control. (B) Relative quantification of the immunoblotting results as calculated by gray scanning (*p
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- Figure 1 Atg16 associates with Cx43 in an early step of autophagosome biogenesis ( a ) Immunoblot for the indicated Cx of homogenates and autophagic vacuoles (AV) isolated from fed or 6h starved (Stv) mice. Quantification of enrichment is shown in Supplementary Fig. 1a . ( b ) Immunofluorescence for LC3 and Atg16 in NRK cells expressing GFP-Cx43 maintained in the presence or absence of serum for 4h. Single channels are shown in reverse black and white and magnification of single and merged images are shown in color. Arrows: colocalization of Atg16/Cx43 (yellow) or Atg16/Cx43/LC3 (white). Quantification is shown in Supplementary Fig. 1c . ( c ) Immunofluorescence for the indicated endogenous proteins in NRK cells maintained in serum-supplemented media without additions (None) or treated with chloroquine (CQ) for 4h. Full fields are shown in Supplementary Fig. 1d . ( d ) Maximum projection confocal microscopy 3D reconstruction (left) followed by a single plane time-lapse acquisition of the region outlined by the white square in HeLa cells expressing EBFP2-Cx43 (pseudocolored in red) and sfGFP-ATG16. ( e ) Immunofluorescence for LC3 and Atg16 in NRK cells expressing GFP-Cx43 but knocked down for Eps15. Single channels are shown in reverse black and white and merged images in color. Inset shows higher magnification. Bottom: Quantification of colocalization between Atg16 and Cx43 (n=3 wells, 4 independent experiments, >20 cells per experiment). Values are mean+s.e.m. (*) p
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- Figure 5 Internalized Cx43 is targeted to recycling endosomes during serum deprivation ( a-c ) Immunofluorescence for the indicated endosomal markers in NRK cells expressing GFP-Cx43 maintained in presence of serum (a ), absence of serum ( b ) or treated with lindane ( c ). Single black and white inverted channels, merged channels and higher magnification insets are shown. ( d ) Immunoblots for indicated proteins in isolated fractions from starved mouse liver HOM: homogenate; LE: late endosomes; CYT: cytosol; APG: autophagosomes; APL: autophagolysosomes. ( e ) Immunoblots for different connexins in homogenates and late endosomes isolated from fed and 6h starved mice. ( f-h ) Fluorescence images of NRK cells expressing GFP-Cx43 maintained in presence of serum (f ), absence of serum ( g ) or treated with lindane ( h ) and incubated with Alexa594-transferrin for 15 minutes before fixation. Top: single and merged channels and boxed area at higher magnification. Bottom: 3D reconstructions and higher magnification details of the boxed areas. Nuclei are highlighted with DAPI. Bars: 5 mum. Uncropped images of blots are shown in Supplementary Fig. 9 .
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- Figure 7 Cx43 modulates formation of pre-autophagosomal structures through direct interaction with autophagy-related proteins ( a ) Co-immunostaining for Cx43 and the indicated Atgs in NRK cells maintained in the presence or absence of serum (top). Single and merged channels of the 3D reconstruction of the boxed regions are shown (bottom). Nuclei are highlighted with DAPI. ( b, c ) Immunoblot for the indicated proteins of immunoprecipitates (IP) of Cx43 in NRK cells maintained in the presence or absence of serum ( b ) or treated or not with 3-methyladenine ( c ) Atg5 is shown as negative control for IP. ( d ) Co-staining for Atg9 and e-cadherin in NRK cells control and knocked down for Cx43. Single and merged channels at higher magnification areas are shown. ( e ) Immunofluorescence for endogenous Atg9 and Cx43 in NRK cells control or knocked down for Eps15. ( f, g ) Immunofluorescence for endogenous Cx43 (green) in NRK cells control or knocked down for Atg14 ( f ) or Atg9 ( g ) maintained in the presence or absence of serum. ( h ) Immunofluorescence of endogenous Cx43 in NRK cells control or knocked down for Atg14 treated (or not) with Tx or Lnd (left). e-cadherin staining (red) is shown to highlight plasma membrane in g and h . Full fields are shown in Supplementary Fig. 6h . Quantification of intracytoplasmic Cx43-positives vesicles (right) (n= 3 wells, 3 independent experiments, >30 cells per experiment). Values are mean+s.e.m and significant for (*) p
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- Figure 8 Depletion of connexins induces autophagosome formation ( a ) Immunoblot for the indicated proteins in mouse embryonic fibroblasts (MEFs) control or knocked down (-) for the three different connexins. ( b ) Immunofluorescence of LC3 in MEFs control (Ctr) or knocked down (-) for three different Cx maintained in the presence or absence of serum. Left: representative fields and higher magnification insets. Nuclei are highlighted with DAPI. Right: Quantification of the average number of LC3-positive puncta per cell (n= 3 wells, 3 independent experiments, >50 cells per experiment). (c) Immunoblot for LC3 in the same cells maintained in the presence of serum untreated (-) or treated with inhibitors of lysosomal proteases (PI) for the indicated times. GAPDH is shown as loading control. ( d ) Representative images of MEFs control or knocked-down (-) for the indicated proteins transfected with the mCherry-GFP-LC3 tandem reporter. Right: quantification of the average number per cell of puncta positive for GFP and mCherry (autophagosomes; APG) and those positive only for mCherry (autophagolysosomes; APL) (n= 3 wells, 3 independent experiments, >50 cells per experiment). ( e ) Electron micrographs of MEFs control or knock-down for the indicated Cx. Insets show autophagic vesicles. Bottom: Quantification of the average number of AV (left) and percentage of cytosolic area (right) occupied by AVs (n= 4 wells, 4 independent experiments, >10 micrographs per well). ( f ) Immunoblot for
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- Figure 3 Immunohistochemical staining of Connexin 43 at different stages of pregnancy . (A) Non-pregnant (group 1), (B) term-pregnant (group 2), (C) in normal labour (group 3), D in prolonged labour (group 4), (E) in normal labour, magnification 1 x 400 with oil, (F) negative control. Magnification in A, B, C, D and F is 1 x 200 Positive staining is brown. The grading of staining is presented in Table 3.
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- Figure 4 Co-localization of Connexin 43 and Syndecan 3 in uterine tissue during normal labour . Sections from uterine tissue from women in normal labour (panel A-C), patients at term (panel D-F) and patients with prolonged labour (panel G-I) were obtained and prepared as described above. A monoclonal antibody against syndecan 3 was added, followed by Alexa Fluor 633 goat anti-rabbit IgG antibody. After that, a Connexin 43 antibody followed by Alexa Fluor 488 rabbit anti-mouse IgG antibody was added. The excitation for Connexin 43 (panel A, D and G) and Syndecan 3 (panel B, E and H) are shown. The merged picture demonstrates the co-localization in the tissue (panel C, F and I).
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- Fig 3 Time-dependent and rapid decrease in Cx43 protein levels in ethanol-treated HL-1 cells. (A-D) Cells were incubated in medium containing 2% ethanol for the indicated time periods, and the protein levels of Cx43, Cx40 and Cx45 were determined by western blot analysis (A). Hsc70 served as a loading control. Quantitative analysis of Cx43 (B), Cx40 (C) and Cx45 (D) is shown. Each graph shows mean+-S.E. (n = 4-6). **, p
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- Figure 8 Effect of hyperglycaemia on staining of immunoreactive Cx proteins in cultured astrocytes Composite z-stacks of confocal images (left column) of immunostained astrocytes showed a low-intensity background and prominent staining of punctate or vesicular immunoreactive material that appeared to be mainly intracellular. This morphological appearance of immunostaining was evident for Cx43 ( A ), Cx30 ( B ) and Cx26 ( C ) protein in astrocytes grown on coverslips for 14 days in a medium containing 5.5 mmol/l glucose; the scale bar is 12.5 mum and applies to all panels. Areas of these immunostained punctate/vesicular objects (right columns) are means (vertical bars represent 1 S.D.) from the following numbers of objects per group: Cx43, 5.5 mmol/l: n = 752 objects in cells on five coverslips; 25 mmol/l: n = 884 objects in cells on five coverslips; Cx30, 5.5 mmol/l: n = 1099 objects, five coverslips; 25 mmol/l: n = 1177 objects, five coverslips; Cx26, 5.5 mmol/l: n = 514 objects, four coverslips; and 25 mmol/l: n = 974 objects, five coverslips.
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- Figure 2 Isolation and characterization of cell sheets from c-kit+ CPC. (a) CPC sheets formed after 3 days of culture detached at room temperature onto thermoresponsive surfaces yielding a scaffold-free monolayered cell sheet. (b) Hematoxylin-eosin staining shows that the cell sheet represents a well-organized structure. CPC in the cell sheets survived, retained the ability to proliferate (Ki67), expressed progenitor cell marker Gata 4, interconnected with each other via connexin-43 gap junctions, and were surrounded extracellular matrix proteins (collagen 1, collagen 3, and fibronectin). (c) Macroscopic visualization of epicardially attached CPC sheet after implantation.
