ABIN362323

antibody from antibodies-online

Targeting: GJA1 CX43, GJAL, ODD, ODDD, ODOD, SDTY3

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362323

Provider

antibodies-online

Product name

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer368) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer368 (R-A-S (p) -S-R) derived from Human Connexin 43. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer368

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Alterations of phosphorylation state of connexin 43 during hypoxia and reoxygenation are associated with cardiac function.

Matsushita S, Kurihara H, Watanabe M, Okada T, Sakai T, Amano A
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006 Mar;54(3):343-53

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Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation.

Solan JL, Fry MD, TenBroek EM, Lampe PD
Journal of cell science 2003 Jun 1;116(Pt 11):2203-11