Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN2847808 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 107-138), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 107-138, N-Term
- Antibody clone number
- RB01369
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.
Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity.
Involvement of the cytoplasmic C-terminal domain of connexin43 in neuronal migration.
Knockdown of microRNA-181 by lentivirus mediated siRNA expression vector decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction.
Gating and regulation of connexin 43 (Cx43) hemichannels.
Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells.
Signal transduction of gap junctional genes, connexin32, connexin43 in human hepatocarcinogenesis.
Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation.
Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells.
Liu X, Sun L, Torii M, Rakic P
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):8280-5
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):8280-5
Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity.
Ponsaerts R, De Vuyst E, Retamal M, D'hondt C, Vermeire D, Wang N, De Smedt H, Zimmermann P, Himpens B, Vereecke J, Leybaert L, Bultynck G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Nov;24(11):4378-95
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Nov;24(11):4378-95
Involvement of the cytoplasmic C-terminal domain of connexin43 in neuronal migration.
Cina C, Maass K, Theis M, Willecke K, Bechberger JF, Naus CC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Feb 18;29(7):2009-21
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Feb 18;29(7):2009-21
Knockdown of microRNA-181 by lentivirus mediated siRNA expression vector decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction.
Li YG, Zhang PP, Jiao KL, Zou YZ
Microvascular research 2009 Dec;78(3):393-404
Microvascular research 2009 Dec;78(3):393-404
Gating and regulation of connexin 43 (Cx43) hemichannels.
Contreras JE, Sáez JC, Bukauskas FF, Bennett MV
Proceedings of the National Academy of Sciences of the United States of America 2003 Sep 30;100(20):11388-93
Proceedings of the National Academy of Sciences of the United States of America 2003 Sep 30;100(20):11388-93
Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells.
Spinella F, Rosanò L, Di Castro V, Nicotra MR, Natali PG, Bagnato A
The Journal of biological chemistry 2003 Oct 17;278(42):41294-301
The Journal of biological chemistry 2003 Oct 17;278(42):41294-301
Signal transduction of gap junctional genes, connexin32, connexin43 in human hepatocarcinogenesis.
Ma XD, Ma X, Sui YF, Wang WL, Wang CM
World journal of gastroenterology 2003 May;9(5):946-50
World journal of gastroenterology 2003 May;9(5):946-50
Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation.
Cameron SJ, Malik S, Akaike M, Lerner-Marmarosh N, Yan C, Lee JD, Abe J, Yang J
The Journal of biological chemistry 2003 May 16;278(20):18682-8
The Journal of biological chemistry 2003 May 16;278(20):18682-8
Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells.
Qin H, Shao Q, Igdoura SA, Alaoui-Jamali MA, Laird DW
The Journal of biological chemistry 2003 Aug 8;278(32):30005-14
The Journal of biological chemistry 2003 Aug 8;278(32):30005-14
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- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC